Showing 241-255 of 518
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Serum levels of perfluoroalkyl substances (PFAS) and body composition - A cross-sectional study in a middle-aged population
Science
1 Feb 2022 | Environ Res
PFOA, PFNA, and PFDA were inversely related to fat mass measurements in women but not men, while PFOS and PFHxS had no consistent associations with body composition.
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Gestational exposure to GenX induces hepatic alterations by the gut-liver axis in maternal mice: A similar mechanism as PFOA
Science
1 Feb 2022 | Sci Total Environ
Gestational exposure to PFOA or GenX induced similar disease indicator changes in maternal livers.
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PFAS Molecules: A Major Concern for the Human Health and the Environment
Science
25 Jan 2022 | Toxics
This review summarizes the current knowledge on PFAS chemistry uses, occurrence, and environmental fate, with a particular emphasis on effects on humans as well as an analysis of the European Union’s efforts to regulate and remediate PFAS.
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Sulfonamide Functional Head on Short-Chain Perfluorinated Substance Drives Developmental Toxicity
Science
25 Jan 2022 | iScience
FBSA exposure leads to changes in DNA that result in abnormal body structure and disrupted gene expression in human model species.
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Demographic, life-style and physiological determinants of serum per- and polyfluoroalkyl substance (PFAS) concentrations in a national cross-sectional survey of Swedish adolescents
Science
17 Jan 2022 | Environ Res
Legacy PFAS were found at elevated levels throughout Swedish adolescents in addition to the novel 9Cl-PF3ONS in 5% of those tested, and females had lower serum PFAS concentration than males.
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Exposure to perfluorooctanoic acid leads to promotion of pancreatic cancer
Science
16 Jan 2022 | Carcinogenesis
PFOA was found to potentially promote pancreatic cancer progression in a mice model.
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Quantitation of linear and branched perfluoroalkane sulfonic acids (PFSAs) in women and infants during pregnancy and lactation
Science
10 Jan 2022 | Environ Int
A linear relation between PFSA concentrations in mothers at pregnancy week 18 and infants at six months was observed, suggesting that pregnancy and lactation are major excretion routes for PFSA, but accumulate in the infant.
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Characterization of Per- and Polyfluorinated Alkyl Substances Present in Commercial Anti-fog Products and Their Adipogenic Activity
Science
10 Jan 2022 | Environ Sci Technol
High concentrations of PFAS were detected in all measured anti-fog products, with FTEOs found to be a significant contributor to the adipogenic activity exhibited by the anti-fog sprays.
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US EPA turns down requests for more PFAS toxicity testing
Policy
30 Dec 2021
The US EPA has deferred or turned down advocacy groups’ requests to require Chemours to conduct toxicity tests on dozens of fluorochemicals found in North Carolina drinking water supplies.
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Environmental pollutant exposure associated with altered early-life gut microbiome: Results from a birth cohort study
Science
20 Dec 2021 | Environ Res
Prenatal exposure to PFAS is associated with alterations to gut microbiome development in infants, with larger effects in breastfed and cesarean-section-born babies.
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Association between maternal serum concentration of perfluoroalkyl substances (PFASs) at delivery and acute infectious diseases in infancy
Science
20 Dec 2021 | Chemosphere
Prenatal exposure to PFAS was associated with increased risks of diarrhea during the first year of life, and these effects were stronger among breastfed infants.
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Relationships between maternal perfluoroalkyl substance levels, polymorphisms of receptor genes, and adverse birth outcomes in the Hokkaido birth cohort study, Japan
Science
20 Dec 2021 | Reprod Toxicol
Maternal PFOS exposure was linked with decreased female infant size.
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The comprehensive analysis based study of perfluorinated compounds-Environmental explanation of bladder cancer progression
Science
20 Dec 2021 | Ecotoxicol Environ Saf
PFAS could promote bladder cancer progression.
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Maternal consumption of ultra-processed foods and newborn exposure to perfluoroalkyl substances (PFAS)
Science
13 Dec 2021 | Cad Saude Publica
Infants were found to have higher levels of PFAS if their mothers ate processed foods at least three times a week.
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Life-Time Environmental Chemical Exposure and Obesity: Review of Epidemiological Studies Using Human Biomonitoring Methods
Science
13 Dec 2021 | Front Endocrinol (Lausanne)
A review of chemical exposure and obesity found that PFOA has consistent obesogenic effects in humans.