Showing 331-345 of 518
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Exposure to isomers of per- and polyfluoroalkyl substances increases the risk of diabetes and impairs glucose-homeostasis in Chinese adults: Isomers of C8 health project
Science
23 Jun 2021 | Chemosphere
Chronic exposure to PFAS isomers was associated with impaired glucose levels and may increase the prevalence of type-2 diabetes in Chinese adults.
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Differential susceptibility of rat primary neurons and neural stem cells to PFOS and PFOA toxicity
Science
16 Jun 2021 | Toxicol Lett
The PFAS-induced alterations in neurons observed in rodents may also impact development and brain disease.
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Associations of perfluoroalkyl and polyfluoroalkyl substances (PFAS) and PFAS mixtures with adipokines in midlife women
Science
9 Jun 2021 | Int J Hyg Environ Health
Some PFAS may alter circulating levels of leptin, affecting the ‘hunger’ sensation.
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Perfluorotridecanoic Acid Inhibits Leydig Cell Maturation in Male Rats in Late Puberty via Changing Testicular Lipid Component
Science
9 Jun 2021 | Chem Res Toxicol
PFTrDA delays the maturation of testicle cells in late puberty mainly by altering the free fatty acid profile.
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Early-life associations between per- and polyfluoroalkyl substances and serum lipids in a longitudinal birth cohort
Science
8 Jun 2021 | Environ Res
Childhood PFAS exposures may be associated with elevated serum lipid concentrations which can be a predictor of later development of hyperlipidemia and cardiovascular disease.
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Exploration of the developmental toxicity of TCS and PFOS to zebrafish embryos by whole-genome gene expression analyses
Science
1 Jun 2021 | Environ Sci Pollut Res Int
PFOS was found to disrupt normal organ development compared to triclosan.
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Evaluating the potential of KOH-modified composite biochar amendment to alleviate the ecotoxicity of perfluorooctanoic acid-contaminated sediment on Bellamya aeruginosa.
Science
25 May 2021 | Ecotoxicol Environ Saf
Both individual and combined PFAS could induce concentration-dependent cell toxicity and depletion of glutathione levels.
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Risk Assessment of Perfluorooctane Sulfonate (PFOS) using Dynamic Age Dependent Physiologically based Pharmacokinetic Model (PBPK) across human lifetime
Science
25 May 2021 | Environ Res
A model was developed to quantify the risk of PFOS throughout the human lifetime, particularly in susceptible age groups.
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Perfluoroalkyl substance pollutants activate the innate immune system through the AIM2 inflammasome
Science
25 May 2021 | Nat Commun
The AIM2 receptor in mice was found to reduce PFOS-induced inflammation, as well as tissue damage in the lungs, livers, and kidneys.
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Perfluoroalkyl and polyfluoroalkyl substances and body size and composition trajectories in midlife women: the study of women's health across the nation 1999-2018
Science
19 May 2021 | Int J Obes (Lond)
Certain PFAS were positively associated with greater body size and body fat and may be an underappreciated contributing factor to obesity risk.
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Maternal exposure of mice to sodium p-perfluorous nonenoxybenzene sulfonate causes endocrine disruption in both dams and offspring
Science
18 May 2021 | Endocr J
Exposure to PFAS was associated with endocrine disruption in mothers and their offspring.
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Exposure to legacy and novel perfluoroalkyl substance disturbs the metabolic homeostasis in pregnant women and fetuses: A metabolome-wide association study
Science
18 May 2021 | Environ Int
A total of 279 features in maternal serum and 338 features in cord serum were identified as metabolites associated with PFAS exposure.
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Study finds alarming levels of ‘forever chemicals’ in US mothers’ breast milk
News
13 May 2021 | The Guardian
The peer-reviewed study detected PFAS in all 50 samples tested with levels ranging from 50ppt to more than 1,850ppt.
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Serum concentrations of per−/polyfluoroalkyl substances and risk of type 2 diabetes: A case-control study
Science
4 May 2021 | Sci. Tot. Env.
PFHxS and PFHpA exposure were associated with an increased risk of developing type 2 diabetes.
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Interference of C6O4 on platelet aggregation pathways: Cues on the new-generation of perfluoro-alkyl substance
Science
4 May 2021 | Environ Int
A PFAS alternative, C6O4, was associated with an increased risk of cardiovascular events.