Showing 346-360 of 518
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Immunotoxicity of Per-and Polyfluoroalkyl Substances: Insights into Short-Chain PFAS Exposure
Science
3 May 2021 | Toxics
Understudied PFAS have toxicological potential but require additional investigation across endpoints and species, including humans, to understand health effects via drinking water exposure.
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Bioactivity Profiling of Per- and Polyfluoroalkyl Substances (PFAS) Identifies Potential Toxicity Pathways Related to Molecular Structure
Science
28 Apr 2021 | Toxicology
Using 142 PFAS, key structural features were associated with receptor activity which can inform the design of new structures devoid of biological activity.
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Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not?
Science
27 Apr 2021 | Crt. Rev. Tox.
This paper aims to present the main issues regarding the modulation of lipid homeostasis by the two most common PFASs, PFOS and PFOA, with emphasis on the underlying mechanisms relevant for humans.
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Life-course exposure to perfluoroalkyl substances in relation to markers of glucose homeostasis in early adulthood
Science
27 Apr 2021 | J Clin Endocrinol Metab
PFOS exposure was associated with decreased insulin sensitivity.
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PFAS-Tox Database
Science
21 Apr 2021
The PFAS-Tox Database was developed as a free, online, publicly available tool to explore the health and toxicology research published on 29 PFAS beyond PFOA and PFOS.
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Lipid responses to environmental perfluoroalkyl substance exposure in a Taiwanese Child cohort
Science
20 Apr 2021 | Environ Pollut
Different lipid patterns were discovered in children exposed to different levels of specific PFASs, such as PFTrDA, PFOS, and PFDA.
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Perfluorooctanesulfonic acid (PFOS) thwarts the beneficial effects of calorie restriction and Metformin
Science
20 Apr 2021 | Toxicol Sci
PFOS exposure inhibited the beneficial effects of diabetes treatments.
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Assessing Indoor Dust Interference with Human Nuclear Hormone Receptors in Cell-Based Luciferase Reporter Assays
Science
19 Apr 2021 | Environ Health Perspect
PFAS was found to exhibit hormonal activities in humans from indoor dust.
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Indoor dust contains PFAS and other toxic chemicals
News
14 Apr 2021 | The Intercept
These are hormonally active compounds that can lead to adverse health effects, including infertility, diabetes, obesity, abnormal fetal growth, and cancers.
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The interplay between environmental exposures and COVID-19 risks in the health of children
Science
7 Apr 2021 | Env. Health
An international group of researchers interested in children’s environmental health was invited to identify knowledge gaps and to develop research questions to close these gaps.
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Perfluoroalkyl substance excretion: Effects of organic anion-inhibiting and resin-binding drugs in a community setting
Science
6 Apr 2021 | Environ. Toxicol. Pharmacol.
Bile acids were found to lower serum PFAS concentrations significantly.
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Following Years Of Advocacy, Gillibrand Joins Community In Hoosick Falls To Announce New Legislation To Create Access To Medical Monitoring For Victims Of Significant PFAS Exposure
Policy
5 Apr 2021
U.S. Senator Kirsten Gillibrand announced legislation to provide Americans with improved legal pathways that would help courts award medical monitoring for victims of PFAS exposure and bolster PFAS research.
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Considering Environmental Exposures to Per- and Polyfluoroalkyl Substances (PFAS) as Risk Factors for Hypertensive Disorders of Pregnancy.
Science
3 Apr 2021 | Environ Res
Pregnant women may be a group that is vulnerable to hypertensive disorders associated with PFAS exposures which should be considered by policymakers setting PFAS exposure limits.
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Regional occurrence of perfluoroalkane substances in human milk for the global monitoring plan under the Stockholm Convention on Persistent Organic Pollutants during 2016-2019
Science
31 Mar 2021 | Chemosphere
PFOA tends to have higher concentrations in wealthier countries.
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Environmental exposure to per- and polyfluoroalkyl substances mixture and male reproductive hormones
Science
30 Mar 2021 | Environ Int
PFAS mixtures were found to inhibit the production of key reproductive hormones in men.