Distribution Characteristics of Per- and Polyuoroalkyl Substances (PFASs) in Human Urines of Acrylic Fiber Plant and Chemical Plant

By Peng, Lin, Wang Xu, Qinghuai Zeng, Yao Cheng, Yingjie Zhang, Ying Guo, Da Chen, Chao Jiang, and Fei Wang
Environ. Sci. Pollut. Res.
June 22, 2021
DOI: 10.21203/rs.3.rs-495306/v1

Per- and polyuoroalkyl substances (PFASs) are persistent and bio-accumulative substances that have many adverse effects on human bodies. This study investigated the PFASs distribution characteristics in urine samples of workers from an acrylic ber plant and a chemical plant. It was found that peruorobutanoic acid (PFBA) was the predominant PFASs both in urine samples from the chemical plant (detection frequency: 86.52%; median value: 39.01 ng/mL) and the acrylic ber plant (detection frequency: 88.16%; median value: 44.36 ng/mL). Meanwhile, peruorooctanoic acid (PFOA) and peruorooctane sulfonic acid (PFOS) were detected with very low frequencies and low concentrations. Furthermore, the results showed that PFASs levels in urine samples of workers from different units of the plants were quite different. PFASs concentrations of urine samples in males were higher than those in females, especially for PFBA, PFHxA, and PFDoA. The age had limited effects on the PFASs distribution in urine samples in this study, as short-chain PFASs were the dominant compounds. The correlations between PFASs concentrations in urine and gender/ages of workers were nally analyzed by Person correlation. The overall results may indicate that short-chain PFASs (such as: PFBA and PFBS) were becoming dominant for human exposure, especially occupational workers.

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