Latest Science

Influence of microplastics on the photodegradation of perfluorooctane sulfonamide (FOSA)

8 Aug 2022 | Res. J. Environ. Sci.

Microplastics could act as PFAS concentrators, making the PFAS more resistant to degradation.

Neurotransmission Targets of Per- and Polyfluoroalkyl Substance Neurotoxicity: Mechanisms and Potential Implications for Adverse Neurological Outcomes

3 Aug 2022 | Chem Res Toxicol

PFAS may be neurotoxic and is associated with chronic and age-related psychiatric illnesses and neurodegenerative diseases.

Outside the Safe Operating Space of a New Planetary Boundary for Per-and Polyfluoroalkyl Substances (PFAS)

2 Aug 2022 | ES&T

PFAS have been detected at unsafe levels in rain globally, leading to the conclusions that the spread of PFOS, PFOA, PFHxS, and PFNA in the atmosphere has exceeded levels of concern for chemical pollution and that PFAS uses and emissions should be rapidly restricted.

The PFAS-Tox Database: A systematic evidence map of health studies on 29 per- and polyfluoroalkyl substances

1 Aug 2022 | Environ. Int.

In this summary of the PFAS-Tox Database we provide examples of data gaps and clusters revealed by the database, with the goal of helping direct future research efforts, facilitate systematic reviews (e.g. on immune effects, mixtures of PFAS, or effects of short chain PFAS), inform regulatory risk assessments, and improve opportunities for cross-disciplinary coordination.

The Association of Per-and Polyfluoroalkyl Substances Serum Levels and Allostatic Load by Country of Birth and the Length of Time in the United States

1 Aug 2022 | Int. J. Environ. Res. Public Health

Foreign-born individuals tend to have higher levels of serum PFAS the longer they stay in the United States.

Leveraging Systematic Reviews to Explore Disease Burden and Costs of Per and Polyfluoroalkyl Substance

1 Aug 2022 | Exposure and Health

This study identified at least $5.5 billion in annual disease burden and social costs due to long-chain PFAS exposure, demonstrating that regulatory actions to limit PFAS use and remediate contaminated water may produce substantial economic benefits.

Uptake of individual and mixed per- and polyfluoroalkyl substances (PFAS) by soybean and their effects on functional genes related to nitrification, denitrification, and nitrogen fixation

29 Jul 2022 | Sci. Total Environ.

The synergistic effect of a PFAS mixture increased the uptake of individual PFAS in soybeans, which led to changes in genes involved in the nitrogen cycle.

Per-and polyfluoroalkyl substances in the atmosphere of waste management infrastructures: Uncovering secondary fluorotelomer alcohols, particle size distribution, and human inhalation exposure

29 Jul 2022 | Environ. Int.

PFAS were prevalent in the air and in particulate matter near landfills and wastewater treatment plants, and modeling demonstrated that fine and ultrafine particles may carry PFAS into the lung alveoli.

Increasing Accumulation of Perfluorocarboxylate Contaminants Revealed in an Antarctic Firn Core (1958–2017)

26 Jul 2022 | ES&T

PFCA and PFBA accumulation in snow increased, and although chemical fluxes of PFOA and PFNA peaked in 2009–2013, there is little evidence of a decline in PFAAs despite supposed recent global curtailments in their production.

Adsorption of per-and polyfluoroalkyl substances (PFAS) to containers

21 Jul 2022 | J. Hazard. Mater.

Containers used to hold PFAS mixtures adsorbed the chemicals at different rates based on PFAS chemistry, container hydrophobicity, temperature, and container manufacturer, with the general trend of PFAS adsorption as polypropylene > HDPE > PET > glass > polystyrene.

Occurrence and Fate of Ultrashort-Chain and Other Per-and Polyfluoroalkyl Substances (PFAS) in Wastewater Treatment Plants

19 Jul 2022 | ACS ES&T Water

The transformation of precursors into shorter chain PFAAs by biological treatment and the partitioning of longer chain PFAS into sludge streams are key factors determining the fate of PFAS in wastewater treatment plants.

Next Generation Per-and Poly-Fluoroalkyl Substances: Status and Trends, Aquatic Toxicity, and Risk Assessment

19 Jul 2022 | EEH

Future uses of PFAS remain uncertain in the face of governmental regulations and production bans, but replacement PFAS will continue to emerge on the world market and in the environment, raising concerns about their general lack of information on mechanisms and toxic potencies.

[Opinion] Speaking the Same Language: The Need for Accurate and Consistent Reporting of Novel Per-and Polyfluoroalkyl Substances

18 Jul 2022 | ES&T

Recommendations presented in this viewpoint are encouraged for all PFAS researchers performing non-targeted analysis to prevent miscommunication and misidentification of PFAS compounds.

Association of increased risk of cardiovascular diseases with higher levels of perfluoroalkylated substances in the serum of adults

18 Jul 2022 | Environ Sci Pollut Res Int

A significant relationship between higher serum PFAS concentrations and an increased risk of cardiovascular disease was observed, mainly in males.

GenX Induces Fibroinflammatory Gene Expression in Primary Human Hepatocytes

15 Jul 2022 | Toxicology

GenX can interfere with metabolic pathways at lower doses and induce abnormal inflammation in human liver cells at higher doses.

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