Latest Science

Determination of Perflourooctanoic Acid Toxicity in a Human Hepatocarcinoma Cell Line

14 Sep 2021 | J Health Pollut.

PFOA is potentially hepatotoxic by triggering programmed cell death.

Modelling the sorption behaviour of perfluoroalkyl carboxylates and perfluoroalkane sulfonates in soils

14 Sep 2021 | Sci Total Environ .

This study develops a new parametric model to predict the sorption of PFAS in soils, which can be linked to the disbursement of these contaminants.

Perfluoroalkyl substances (PFAS) in drinking water and risk for polycystic ovarian syndrome, uterine leiomyoma, and endometriosis: A Swedish cohort study

14 Sep 2021 | Environ Int .

Exposure to high levels of PFAS in drinking water was associated with an increased risk of reproductive harm

Harnessing electronic health records to study emerging environmental disasters: a proof of concept with perfluoroalkyl substances (PFAS)

14 Sep 2021 | NPJ Digit Med

This proof-of-concept study confirms that health records can be used to study human health and disease impacts of environmental disasters and produces equivalent disease-exposure knowledge to prospective epidemiology studies while remaining cost-effective.

Can Environmental Law Solve the 'Forever Chemical' Problem?

14 Sep 2021 | Wake Forest Law Review, Forthcoming

A proposal away from the reactive toxicity honor system in favor of a precautionary approach to environmental protection.

Temporal trends of perfluoroalkyl substances in an Australian wastewater treatment plant: A ten-year retrospective investigation

14 Sep 2021 | Sci. Tot. Env.

PFBA and 5:3 FTCA showed increasing concentrations between 2010 and 2020 with over 50% coming from industrial inputs.

Exposure to per- and polyfluoroalkyl substances associates with an altered lipid composition of breast milk

14 Sep 2021 | Environ Int

Maternal exposure to PFAS impacts the nutritional quality of breast milk, which, in turn, may have a detrimental impact on the health and growth of the children later in life.

Prenatal and postnatal exposure to PFAS and cardiometabolic factors and inflammation status in children from six European cohorts.

14 Sep 2021 | Environ Int

Prenatal, rather than postnatal, PFAS exposure might contribute to increased obesity in children.

Evaluation of the acute toxicity and neurodevelopmental inhibition of perfluorohexanoic acid (PFHxA) in zebrafish embryos

14 Sep 2021 | Ecotoxicol Environ Saf

High levels of PFHxA exposure was associated with permanent neurological damage in a human model organism.

Comparative characterization of microbial communities that inhabit PFAS-rich contaminated sites: A case-control study

14 Sep 2021 | J Hazard Mater

Soil microbial communities were found to have adverse reactions to PFAS which may put crops at risk.

Exposure to Perfluoroalkyl Substances and Glucose Homeostasis in Youth

8 Sep 2021 | Environ Health Perspect

Youth exposure to PFHxS was associated with abnormal metabolism in females, especially after puberty.

Exposure to a mixture of legacy, alternative, and replacement per- and polyfluoroalkyl substances (PFAS) results in sex-dependent modulation of cholesterol metabolism and liver injury

8 Sep 2021 | Environ Int

Exposure of mice to a mixture of PFAS results in abnormal modulation of cholesterol levels leading to increased liver weight and inflammation.

Systemic toxicity induced by topical application of heptafluorobutyric acid (PFBA) in a murine model

8 Sep 2021 | Food Chem Toxicol

Sustained dermal exposure to PFBA induces liver toxicity and raises concerns of short-chain PFAS being promoted as safer alternatives.

The role of maternal high fat diet on mouse pup metabolic endpoints following perinatal PFAS and PFAS mixture exposure

8 Sep 2021 | Toxicology

PFAS mixtures were found to have increased detrimental effects, especially when transferred from mother to offspring.

Use of glioma to assess the distribution of patterns of perfluoroalkyl and polyfluoroalkyl substances in human brain

8 Sep 2021 | Environ Res

PFAS, including short chains, were found inside the brain circumnavigating the blood-brain barrier.

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