Latest Science

Toxicological Response of Chironomus dilutus in Single Chemical and Binary Mixture Exposure Experiments with Six Perfluoralkyl Substances

13 Apr 2021 | Environ Toxicol Chem

PFOS was found to be the most toxic PFAS to aquatic life and suggests that PFOS could be more toxic to freshwater insects than previously reported.

Joint effects of prenatal exposure to per- and poly-fluoroalkyl substances and psychosocial stressors on corticotropin-releasing hormone during pregnancy

13 Apr 2021 | J Expo Sci Environ Epidemiol

PFAS was associated with higher levels of stress hormones which affected joints in pregnant women.

Per- and polyfluoroalkyl Substances (PFAS) as Contaminants of Emerging Concern in Asia's Freshwater Resources

13 Apr 2021 | Environ Res

The highest PFAS contamination was detected in surface water relative to ground, tap, and drinking water.

Occurrence and sources of per- and polyfluoroalkyl substances in the ice-melting lakes of Larsemann Hills, East Antarctica

13 Apr 2021 | Sci Total Environ

In the ice-melting lakes, PFOA, PFOS, and Cl-PFESA were detected in ice-melt lakes on the eastern side of Antarctica where there are fewer on-site human activities.

In-Vitro and In-Silico Assessment of Per- and Polyfluoroalkyl Substances (PFAS) in Aqueous Film-Forming Foam (AFFF) Binding to Human Serum Albumin

13 Apr 2021 | Toxics

Carboxylic acid and sulfonic acid-containing PFAS were found to bioaccumulate the most readily in human blood.

Time Trend of Persistent Organic Pollutants and Metals in Greenlandic Inuit during 1994-2015

13 Apr 2021 | Int J Environ Res Public Health

PFOS, PFHxS, and PFOA decreased across Greenland while PFNA, PFDA, and PFUnDA increased in women.

Investigating Molecular Mechanisms of Immunotoxicity and the Utility of ToxCast for Immunotoxicity Screening of Chemicals Added to Food

13 Apr 2021 | Int J Environ Res Public Health

PFAS show weak or no activity in immune-related ToxCast assays, which differs from traditional toxicological studies.

Biological and behavioural responses of European honey bee (Apis mellifera) colonies to perfluorooctane sulfonate (PFOS) exposure

12 Apr 2021 | Integr Environ Assess Manag

PFOS exposure adversely affects honey bee colonies and may transfer to honey.

The interplay between environmental exposures and COVID-19 risks in the health of children

7 Apr 2021 | Env. Health

An international group of researchers interested in children’s environmental health was invited to identify knowledge gaps and to develop research questions to close these gaps.

Considerations for Toxicity Experiments and Risk Assessments with PFAS Mixtures

7 Apr 2021 | IEAM

This perspective article discusses available approaches for mixtures risk assessment with a specific focus on application to PFAS mixtures.

Exploring Unknown Per- and Polyfluoroalkyl Substances in the German Environment – the Total Oxidizable Precursor Assay as Helpful Tool in Research and Regulation

7 Apr 2021 | Sci. Total Environ.

Time trend analysis showed decreasing trends for most detected PFAS since 2005 with the results demonstrating that target analysis detects only a minor fraction of the PFAS burdens in environmental samples.

PFAS accumulation in indigenous and translocated aquatic organisms from Belgium, with translation to human and ecological health risk

7 Apr 2021 | Environ. Sci. Eur.

In mussels, PFAS profiles were dominated by PFOA and showed a higher relative contribution of short-chained PFAS, while PFAS profiles in fish were dominated by PFOS.

Human exposure pathways to poly- and perfluoroalkyl substances (PFAS) from indoor media: A systematic review protocol

7 Apr 2021 | Environ. Int

An adapted protocol was developed to utilize existing systematic review tools for exposure science questions concerning PFAS.

Per- and Polyfluoroalkyl Substance (PFAS) Transport from Groundwater to Streams near a PFAS Manufacturing Facility in North Carolina, USA

7 Apr 2021 | Environ Sci Technol

The mass transfer between groundwater and surface water of PFAS was quantified for contaminated communities.

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