Per-And Poly-Fluoroalkyl Substances (PFAS) Exposure and Risk of Breast, and Female Genital Cancers: A Systematic Review and Meta-Analysis
19 Dec 2024 | Med Lav.
Exposure to PFAS may be associated with an increased risk of ovarian cancer and a potential link to breast cancer, though further research is needed to clarify these relationships.
Presence of Perfluorohexanoic Acid in Fluoroelastomer Watch Bands
18 Dec 2024 | Environ. Sci. Technol. Lett.
The detection of high PFHxA concentrations in fluoroelastomer watch bands raises significant concerns about dermal exposure and potential health impacts, emphasizing the need for further studies on its absorption and toxicity.
Late lessons from early warnings on PFAS
17 Dec 2024 | Nature Water
Recent PFAS regulations in the U.S. and Europe highlight the need for significant investment by water providers, innovation to avoid harmful replacements, and reforms to regulatory approaches that have historically focused on case-by-case assessments anddelayed action despite early warnings of PFAS persistence, bioaccumulation, and toxicity.
Disclosure of Conflict of Interest Regarding the paper “Per- and Poly-fluoroalkyl Substances (PFAS) Exposure and Risk of Kidney
16 Dec 2024 | Medicina del Lavoro
A letter to the editor raising a conflict of interest regarding a co-author of a previously published review paper on the associations between PFAS exposure and possible cancer risk.
Per-and polyfluoroalkyl substances in paired serum and breastmilk samples among pregnant farmworkers in Thailand
16 Dec 2024 | Int. J. Hyg. Environ. Health.
PFOS and PFNA were the most commonly detected PFAS in breastmilk from Thai farmworkers, with lactational transfer efficiencies up to 14.7%, highlighting a significant route of postnatal exposure for infants.
Early-life exposure to PCBs and PFAS exerts negative effects on the developing Central Nervous System
16 Dec 2024 | J. Hazard. Mater.
Early-life exposure to PCBs and PFAS disrupts brain development by impairing the blood-brain barrier, causing oxidative stress, and altering neurodevelopmental processes, potentially leading to cognitive deficits, neuropsychiatric disorders, and endocrine disruption.
The Relationship Between Maternal Exposure to Endocrine-Disrupting Chemicals and the Incidence of Congenital Heart Diseases: A Systematic Review and Meta-Analysis
16 Dec 2024 | Metabolites
PFAS can disrupt the endocrine system by binding to nuclear hormone receptors such as estrogen and androgen receptors, potentially interfering with hormone signaling pathways that regulate reproductive, metabolic, and developmental processes. Here, a model was developed to predict how strongly different PFAS bind to these receptors.
Associations of early life per- and polyfluoroalkyl substances (PFAS) exposure with body mass index and risk of overweight or obesity at age 2-18 years: Mixture analysis in the prospective Boston Birth Cohort
15 Dec 2024 | Environ Int
Early-life exposure to PFAS is associated with an increased risk of childhood obesity, with effects influenced by maternal pre-pregnancy obesity, child age, and PFAS mixture, highlighting the need for further investigation into long-term health impacts and preventive strategies.
[EDITORIAL] Fluoropolymers and nanomaterials, the invisible hazards of cell phone and computer touchscreens
11 Dec 2024 | Environ Chem Lett
Nanomaterials and fluoropolymers in touchscreen coatings, designed to repel smudges, pose hidden risks of toxicity and environmental harm as they degrade and transfer to users' skin, especially affecting children and frequent users.
Occurrence, Transport, and Full-Scale Adsorptive Removal of PFAS in Electroplating Parks in China
11 Dec 2024 | Environ. Sci. Technol.
Granular activated carbon and hydrophobic anion exchange resin were found to effectively remove up to 98.2% of PFAS from electroplating wastewater in China, reducing annual PFAS discharge by 5030–8000 kg. Anion exchange resin showed higher efficiency but lower selectivity for certain PFAS.
Impacts of Gestational F-53B Exposure on Fetal Neurodevelopment: Insights from Placental and Thyroid Hormone Disruption
11 Dec 2024 | Environ Health (Wash)
Exposure to the PFOS replacement chemical F-53B during pregnancy led to its accumulation in the placenta and fetal brain, disrupting thyroid hormone transport and gene regulation, ultimately causing fetal growth issues and impaired brain development in mice.
Individual and joint associations of exposure to per- and polyfluoroalkyl substances with children's mitochondrial DNA copy number, and modified by estimated glomerular filtration rate
10 Dec 2024 | Environ Res
Legacy and emerging PFAS, especially PFOA, were associated with lower levels of mitochondrial DNA in children, with more pronounced associations seen in those with weaker kidney function and older age, highlighting the potential health risks of PFAS exposure in early life.
PFAS-Free Energy Storage: Investigating Alternatives for Lithium-Ion Batteries
4 Dec 2024 | Environ. Sci. Technol.
Alternatives to PFAS in lithium-ion batteries include bio-based polymers, fluorine-free ionic liquids, and siloxane-based compounds, all designed to provide similar thermal and chemical stability without the environmental persistence and toxicity of PFAS.
Per- and polyfluoroalkyl substances, apolipoproteins and the risk of coronary heart disease in US men and women
3 Dec 2024 | Environ Health
Elevated concentrations of PFOS in the blood were strongly associated with an increased risk of coronary heart disease, with the risk more than tripling for each unit increase in PFOS levels.
Residential Garden Produce Harvested Near a Fluorochemical Manufacturer in North Carolina Can Be An Important Fluoroether Exposure Pathway
2 Dec 2024 | J. Agric. Food Chem.
Residential garden produce grown near a fluorochemical manufacturing plant in North Carolina was found to contain significant levels of PFAS, predominantly low-molecular-weight PFEAs such as PMPA, PFO2HxA, PFMOAA, and GenX, with water-rich produce showing the highest contamination, posing potential dietary exposure risks for local communities.