Solvent Suitability for HFPO-DA (“GenX” Parent Acid) in Toxicological Studies

27 May 2020 | ES&T L

GenX was found to degrade in common laboratory solvents suggesting the need for caution when performing or using data from toxicity assessments on it and other closely related PFAS.

Removal of per- and polyfluoroalkyl substances (PFASs) in a full-scale drinking water treatment plant long-term performance of granular activated carbon (GAC) and influence of flow-rate

27 May 2020 | Water Res.

The results and methods presented in this study give drinking water providers valuable tools for the operation of a full-scale treatment train for the removal of PFAS in contaminated raw water.

Perfluoroalkyl Substances Exposure and Hearing Impairment in US Adults

27 May 2020 | Environ. Res.

PFNA and PFDA were associated with high-frequency hearing impairment, while PFOS and PFOA were not.

Interactions of perfluorooctanesulfonate (PFOS) and 6:2 chlorinated polyfluorinated ether sulfonate (6:2 Cl-PFESA) with human serum albumin (HSA): A comparative study

27 May 2020 | Chem. Res. Toxicol.

The stronger binding affinity of 6:2 Cl-PFESA to human blood cells may contribute to its higher bioaccumulation potential than PFOS.

Integrative omics analyses uncover the mechanism underlying the immunotoxicity of perfluorooctanesulfonate in human lymphocytes

27 May 2020 | Chemosphere

The findings of this study offer insight into the molecular mechanisms underlying the immunotoxicity of PFOS and open the potential of using the identified PFOS-responsive genes and lipids as biomarkers for risk assessment.

Legacy and emerging per- and polyfluoroalkyl substances (PFASs) in the coastal environment of Korea: Occurrence, spatial distribution, and bioaccumulation potential

27 May 2020 | Chemosphere

Seawater was dominated by short-chained PFASs as a prompt reflection of regulation, while the sediment and bivalves were dominated by long-chained PFASs.

Screening new persistent and bioaccumulative organics in China's inventory of industrial chemicals

27 May 2020 | Environ. Sci. Technol.

Sixty-nine organofluorine compounds with three or more perfluorinated moieties, were found unique to the chemical Inventory of Existing Chemical Substances of China lists.

Understanding and Managing the Potential By‐Products of PFAS Destruction

26 May 2020 | Ground. Mon. & Rem.

Based on the available technologies relevant to PFAS destruction, complex aqueous solutions containing high concentrations of PFAS have the potential to generate either known short-chain PFAAs or other secondary effects on water quality.

Per- and polyfluoroalkyl substances (PFASs) in blood of captive Siberian tigers in China: Occurrence and association with biochemical parameters

19 May 2020 | Env Poll

Ten PFASs were detected in the blood of captive Siberian tigers, including PFOS alternative 6:2 Cl-PFESA, primarily from the consumption of PFAS-contaminated meat.

Removal of eight perfluoroalkyl acids from aqueous solutions by aeration and duckweed

19 May 2020 | Sci the Total Env

With duckweed, >95% of long chain PFAS at 200 ppb were removed after 2 weeks.

Perfluoroalkyl Substance Exposure Was Negatively Associated With Cortisone Levels in Pregnancy

19 May 2020 | J Endocr Soc

Early pregnancy concentrations of maternal PFAS were inversely associated with late pregnancy cortisone levels, indicating potential endocrine disruption in highly exposed mothers.

Investigation of Levels of Perfluoroalkyl Substances in Surface Water, Sediment and Fish Tissue in New Jersey, USA

19 May 2020 | Sci of Total Env

PFOS, PFDA, PFUnA, and PFDoA were the predominant PFAS detected in fish tissue with the highest levels downstream of a military facility.

Association of perfluoroalkyl substances with gestational hypertension and preeclampsia in the MIREC study.

19 May 2020 | Environ Int

Higher levels of PFHxS were associated with the development of preeclampsia during pregnancy.

Adverse effects of in vitro GenX exposure on rat thyroid cell viability, DNA integrity and thyroid-related genes expression.

19 May 2020 | Environ. Pollut.

GenX exposure is associated with endocrine disruption by damaging the thyroid cell's DNA.

Challenges in the analytical determination of ultra-short-chain perfluoroalkyl acids and implications for environmental and human health

19 May 2020 | Anal Bioanal Chem

The present review gives an overview of the currently used analytical methods and summarizes the findings regarding potential analytical challenges regarding ultra-short-chain PFAS.