Aerobic Biotransformation and Defluorination of Fluoroalkylether Substances (ether PFAS): Substrate Specificity, Pathways, and Applications

7 Aug 2023 | Environ. Sci. Technol. Lett.

This study investigated the structure–biodegradability relationship for 12 different ether PFAS with a carboxylic acid headgroup in activated sludge.

[Discussion] Perfluorohexyloctane: Do we really need a PFAS for the treatment of Dry Eye Disease?

7 Aug 2023 | Sci. Total Environ.

The researchers argue that non-pharmacological strategies and traditional artificial tears, which lack environmental risks, should be tried as treatments before eye drops that are composed entirely of PFAS.

Microplastics as carriers of per-and polyfluoroalkyl substances (PFAS) in aquatic environment: Interactions and ecotoxicological effects

4 Aug 2023 | Water Emerging Contaminants & Nanoplastics

This review covers the PFAS sorption onto microplastics, the ecological consequences of ingesting PFAS-contaminated microplastics, and their synergistic effects on aquatic life.

Discussion. Has the human population become an sentinel for the adverse effects of PFAS contamination on wildlife health and endangered species?

2 Aug 2023 | Sci Total Environ

PFAS are detected in wildlife globally, with international efforts needed to restrict PFAS discharges into the environment and to clean up PFAS-contaminated sites in order to protect wildlife from chemical pollution and advance species conservation.

Prenatal exposure to perfluoroalkyl substances and inflammatory biomarker concentrations

31 Jul 2023 | Environ. Epidemiol

PFOA, PFOS, and PFHxS, individually and as a mixture, were positively associated with inflammatory responses during pregnancy.

Physiological effects of PFAS exposure in seabird chicks: A multi-species study of thyroid hormone triiodothyronine, body condition and telomere length in South Western France

30 Jul 2023 | Sci Total Environ

PFAS may interfere with the physiology of chicks during their developmental periods, potentially inducing long-lasting consequences.

Per-and polyfluoroalkyl substances (PFAS) as a health hazard: Current state of knowledge and strategies in environmental settings across Asia and future perspectives

29 Jul 2023 | J. Chem. Eng.

This review discussed the current knowledge of PFAS in Asian countries and how the lack of a regulatory framework has exposed millions of people to the potential negative health impacts of PFAS.

Exposure characteristics of legacy and novel per- and polyfluoroalkyl substances in blood and association with hypertension among low-exposure population

29 Jul 2023 | J Hazard Mater

Among participants with low levels of PFAS exposure, PFHxA showed a positive association with risk of hypertension, while a novel PFAS, 6:2 Cl-PFESA, showed a negative association.

Fetal Glucocorticoid Mediates the Association between Prenatal Per- and Polyfluoroalkyl Substance Exposure and Neonatal Growth Index: Evidence from a Birth Cohort Study

26 Jul 2023 | Environ Sci Technol

Fetal hormone levels were found to influence the association between mothers’ PFAS levels and fetal growth.

Per- and polyfluoroalkyl substances in ambient fine particulate matter in the Pearl River Delta, China: Levels, distribution and health implications

25 Jul 2023 | Env Poll

PFAS exposure via inhalation of particulate matter was found to be dominated by low levels of PFSAs and PFCAs, but inhalation exposure is still important due to its long-term and cumulative nature.

Environmental explanation of prostate cancer progression based on the comprehensive analysis of perfluorinated compounds

25 Jul 2023 | Ecotoxicol Environ Saf

PFOA and PFNA were found to promote the growth of prostate cancer cells.

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonates Exert Stronger Thyroid Homeostasis Disruptive Effects in Newborns than Perfluorooctanesulfonate: Evidence Based on Bayesian Benchmark Dose Values from a Population Study

25 Jul 2023 | Environ Sci Technol

Models suggested that 6:2 Cl-PFESA, an alternative to PFOS, has a stronger impact on newborns’ thyroids compared to PFOS and other legacy PFAS.

Examining the impact of nanoplastics and PFAS exposure on immune functions through inhibition of secretory immunoglobin A in human breast milk

22 Jul 2023 | J Hazard Mater

The presence of nanoplastics and PFAS in breast milk was computationally found to likely impair infants’ immune systems.

[Editorial] Innovate beyond PFAS

20 Jul 2023 | Science

Scheringer argues that persistence should be seen as a part of chemical hazards and that the current overuse of PFAS is detrimental to sustainability and a roadblock to innovation.

Current Review of Increasing Animal Health Threat of Per- and Polyfluoroalkyl Substances (PFAS): Harms, Limitations, and Alternatives to Manage Their Toxicity

20 Jul 2023 | Int J Mol Sci

The review highlights the persistence of PFAS in the environment, their potential health effects on both humans and animals, and the need for further research and countermeasures to mitigate their impact, especially on animals.