Prenatal exposure to per- and polyfluoroalkyl substances and childhood autism-related outcomes

12 Jan 2023 | Epidemiology

Mothers’ prenatal blood concentrations of PFNA may be associated with modest increases in their child’s autism-related traits.

PFAS Biotransformation Pathways: A Species Comparison Study

12 Jan 2023 | Toxics

A metabolic pathway map was made to aid researchers in determining possible PFAS breakdown products in fish when no metabolic data is present.

A Proposed approach to defining per- and polyfluoroalkyl substances (PFAS) based on molecular structure and formula

11 Jan 2023 | Integr Environ Assess Manag

A definition of PFAS was proposed based on four substructures and any structures where the molecular formula is at least 30% fluorine by atom count.

Occurrence and implications of per and polyfluoroalkyl substances in animal feeds used in laboratory toxicity testing

10 Jan 2023 | Sci Total Environ

PFAS contamination in animal feed was found to be pervasive, which is significant because unintended PFAS exposure in control animals from feed can significantly bias toxicity testing.

In utero exposure to perfluoroalkyl substances and early childhood BMI trajectories: A mediation analysis with neonatal metabolic profiles

9 Jan 2023 | Sci Total Environ

Prenatal PFAS exposure was associated with persistently increased BMI in childhood.

Rapid Determination of Selected PFAS in Textiles Entering the Waste Stream

6 Jan 2023 | Toxics

A rapid extraction and clean-up method was developed for the determination of 21 PFAS in various polymers used in soft furnishings and upholstery.

Associations between per and polyfluoroalkyl ether sulfonic acids and vitamin D biomarker levels in Chinese newborns

5 Jan 2023 | Sci Total Environ

Exposure to legacy PFAS, including PFTrDA, PFHxS, and PFOS, might disturb vitamin D status in newborns.

Per- and polyfluoroalkyl substances (PFAS) presence in food: Comparison among fresh, frozen and ready-to-eat vegetables

5 Jan 2023 | Food Chem

Italian ready-to-eat vegetables contained higher PFAS levels than fresh/frozen products, and organic vegetables had lower PFAS contents than their traditional counterparts.

Emerging and legacy contaminants in common minke whale from the Barents sea

4 Jan 2023 | Environ Pollut

PFAS levels were higher in fetuses than male or female adult whales, and PFOS levels were higher than those detected from the same population eight years previously.

Contact to perfluoroalkyl substances and thyroid health effects: A meta-analysis directing on pregnancy

4 Jan 2023 | Chemosphere

A systematic review found that PFOS, PFOA, and PFDA exposures were associated with thyroid disruption in pregnant women, who were more sensitive to PFAS exposure in the first six months of pregnancy.

Early-life exposure to per- and polyfluoroalkyl substances and infant gut microbial composition

3 Jan 2023 | Environ. Epi.

PFAS may increase infant gut microbiome diversity, which has been associated with an increased risk of infection.

Per- and polyfluoroalkyl substances (PFAS) in breast milk and infant formula: A global issue

3 Jan 2023 | Environ. Res.

Breast milk concentrations of PFOA and PFOS often exceed children’s drinking water screening values, and limited information on infant formula means that families cannot generally know whether their infant’s exposures exceed safe levels.

Analytical method interferences for perfluoropentanoic acid (PFPeA) and perfluorobutanoic acid (PFBA) in biological and environmental samples

30 Dec 2022 | Chemosphere

Researchers recommend adjustments to analytical methods investigating PFBA and PFPeA due to chemical interferences from fatty acids in biological and environmental samples.

A systematic evidence map of chronic inflammation and immunosuppression related to per-and polyfluoroalkyl substance (PFAS) exposure

30 Dec 2022 | Environ Res

Several PFAS commonly found in the environment may induce immunosuppression and chronic inflammation, two key characteristics of carcinogens.

Concentrations of Per- and Polyfluoroalkyl Substances in Paired Maternal Plasma and Human Milk in the New Hampshire Birth Cohort

27 Dec 2022 | Environ Sci Technol

Maternal PFOA and PFOS serum concentrations correlated with milk concentrations, and while milk concentrations were lower, about 6.5% of infants were estimated to be exposed to enough PFAS via milk to have long-term health impacts.