Blood Concentrations of Per-and Polyfluoroalkyl Substances are Associated with Autoimmune-like Effects in American Alligators from Wilmington, North Carolina

20 Oct 2022 | Frontiers in Toxicology

PFAS was found to broadly alter immune activities resulting in autoimmune-like diseases in American alligators.

Prenatal exposure to perfluorooctane sulfonate alternatives and associations with neonatal thyroid stimulating hormone concentration: A birth cohort study

20 Oct 2022 | Chemosphere

Higher concentrations of prenatal PFBS was associated with lower developmental hormone concentrations in newborns.

[Perspective] EPA Takes Action Against Harmful "Forever Chemicals" in the US Water Supply

19 Oct 2022 | JAMA

This Medical News article discusses new EPA advisories for PFAS as well as new National Academies guidance on expanded testing for exposure.

Exposure to a mixture of per-and polyfluoroalkyl substances modulates pulmonary expression of ACE2 and circulating hormones and cytokines

18 Oct 2022 | Toxicol Appl Pharmacol

The effects of PFAS exposure in mice on gene expression and hormones were studied with respect to susceptibility to viral infections such as COVID-19.

Analysis of Per- and Poly(fluoroalkyl) Substances (PFASs) in Highly Consumed Seafood Products from U.S. Markets

17 Oct 2022 | J Agric Food Chem

Bottom-feeding organisms tend to have the highest PFAS concentrations, followed by lean fish, fatty fish, and aquaculture with PFUdA and PFDoA being the most frequently detected chemicals.

Plasma concentrations of perfluoroalkyl acids and their determinants in youth and adults from Nunavik, Canada

14 Oct 2022 | Chemosphere

Long-chain PFAAs levels were 4–7 fold higher in Nunavik Inuit adults compared to the Canadian population and were associated with hunting activity, omega-3 fatty acids, and drinking water from environmental sources.

Per- and polyfluoroalkyl substances and psychosocial stressors have a joint effect on adverse pregnancy outcomes in the Atlanta African American Maternal-Child cohort

14 Oct 2022 | Sci Total Environ

Psychosocial stress including depression, anxiety, stress, and gendered racial stress may amplify associations between an increase in PFAS and reduced birthweight.

Occurrences of legacy and emerging per-and polyfluoroalkyl substances in human milk in China: Results of the third National Human Milk Survey (2017–2020)

12 Oct 2022 | J. Hazard. Mater.

Potential hazard from PFAS exposure through breastmilk, especially from high PFOA exposure, was observed throughout China.

Presumptive Contamination: A New Approach to PFAS Contamination Based on Likely Sources

12 Oct 2022 | ES&T

A contamination model was used to create a map of presumptive PFAS contamination sites in the United States, identifying more than 57,000 sites including industrial facilities, wastewater treatment plants, current or former military sites, and airports.

Use and release of per-and polyfluoroalkyl substances (PFASs) in consumer food packaging in US and Canada

11 Oct 2022 | Chemosphere

Most food packaging does not contain intentionally added PFAS, indicating that PFAS are not necessary for food packaging, yet the thousands of tonnes of PFAS still used have the potential to contaminate the environment and waste streams.

Swimming with PFAS in public and private pools

11 Oct 2022 | Chemosphere

PFBA, PFHxA, PFHpA, PFOA, PFNA and PFBS were detected in every pool sample with most PFOA and PFOS levels above the new US EPA drinking water health advisory limits.

Targeted analysis and total oxidizable precursor assay of several insecticides for PFAS

10 Oct 2022 | JHM Letters

PFOS was detected in 6 out of 10 tested insecticides at concentrations up to 19,200,000 ppt, with 7 additional PFAS found via non-targeted techniques.

An unexpected synergistic toxicity caused by competitive bioconcentration of perfluoroalkyl acid mixtures to Daphnia magna: Further promoted by elevated temperature

7 Oct 2022 | Environ Pollut

High temperatures promote the bioconcentration of PFAA and resulted in the increased toxicity of PFAA mixtures in model species.

An Integrated Approach for Determination of Total Per-and Polyfluoroalkyl Substances (PFAS)

5 Oct 2022 | Environ. Sci. Technol.

This paper describes how to use methods like the total oxidizable precursor assay and suspect screening to more fully characterize PFAS present in soil and aqueous mixtures as such screenings can help inform the potential for PFAS exposure.

Maternal Exposure to Per- and Polyfluoroalkyl Substances (PFAS) and Male Reproductive Function in Young Adulthood: Combined Exposure to Seven PFAS

5 Oct 2022 | Environ Health Perspect

Consistent inverse associations between exposure to maternal PFAS and semen quality were found in a sample of the Danish population.