Distribution, sources, and dietetic-related health risk assessment of perfluoroalkyl acids (PFAAs) in the agricultural environment of an industrial-agricultural interaction region (IAIR), Changshu, East China
20 Dec 2021 | Sci Total Environ
Textiles and food industries may contribute to PFAAs in agricultural environments, which can lead to high PFAS contamination in local fish and vegetables.
Development and validation of an LC-MS/MS method for the quantitation of 30 legacy and emerging per- and polyfluoroalkyl substances (PFASs) in human plasma, including HFPO-DA, DONA, and cC6O4
20 Dec 2021 | Anal Bioanal Chem
An assay was developed suitable for large-scale analyses of a wide range of legacy and emerging PFAS in human plasma.
Understanding the dynamics of physiological changes, protein expression, and PFAS in wildlife
20 Dec 2021 | Environ Int
This review shares general information with the PFAS research community on what biotic and abiotic changes might be important to consider when designing and interpreting biomonitoring or an ecotoxicity-based wildlife study.
Extractable organofluorine analysis: A way to screen for elevated per- and polyfluoroalkyl substance contamination in humans?
19 Dec 2021 | Environ Int
Extractable organofluorine analysis was found to be an accurate screening method for detecting high PFAS levels in human blood.
Investigation of per-and polyfluoroalkyl substances (PFAS) in soils and sewage sludges by fluorine K-edge XANES spectroscopy and combustion ion chromatography
13 Dec 2021 | Environ Sci Pollut Res Int
Sewage sludge was found to be the second most important contributor of PFAS in agriculture behind soils.
Fluoroalkylether compounds affect microbial community structures and abundance of nitrogen cycle-related genes in soil-microbe-plant systems
13 Dec 2021 | Ecotoxicol. Environ. Saf.
Different ether-PFAS affected soil microbial community structure and function, sometimes inhibiting the ability of bacteria to transform environmental nitrogen.
A Bad Start in Life? Maternal Transfer of Legacy and Emerging Poly- and Perfluoroalkyl Substances to Eggs in an Arctic Seabird
13 Dec 2021 | Environ Sci Technol
Researchers identified 7:3 fluorotelomer carboxylic acid in 84% of seabird egg yolks and provided the first documented finding of ADONA in wildlife.
Montmorillonite clay-based sorbents decrease the bioavailability of per- and polyfluoroalkyl substances (PFAS) from soil and their translocation to plants
13 Dec 2021 | Environ Res
The addition of amended clay to soils was found to reduce the uptake of PFAS into edible crops by up to 74%.
Maternal consumption of ultra-processed foods and newborn exposure to perfluoroalkyl substances (PFAS)
13 Dec 2021 | Cad Saude Publica
Infants were found to have higher levels of PFAS if their mothers ate processed foods at least three times a week.
Life-Time Environmental Chemical Exposure and Obesity: Review of Epidemiological Studies Using Human Biomonitoring Methods
13 Dec 2021 | Front Endocrinol (Lausanne)
A review of chemical exposure and obesity found that PFOA has consistent obesogenic effects in humans.
The use of in vitro methods in assessing human health risks associated with short-chain perfluoroalkyl and polyfluoroalkyl substances (PFAS)
13 Dec 2021 | J Appl Toxicol
This review summarizes the PFAS toxicity data obtained using human cells in vitro, discusses the advantages and limitations of cell-based models, and provides thoughts on potential solutions to the challenges of these methods.
PFOA induces alteration in DNA methylation regulators and SARS-CoV-2 targets and in mouse lung tissues
12 Dec 2021 | Toxicol Rep
PFOA was found to change gene expression in lungs, potentially increasing susceptibility to COVID-19.
Tumorigenic activity of alternative per- and polyfluoroalkyl substances (PFAS): Mechanistic in vitro studies
6 Dec 2021 | Sci Total Environ
PFHxS has been associated with breast cancer in epidemiological studies, and this study demonstrated how this shorter-chain PFAS can affect cell proteins and cell proliferation.
Exposure of male mice to perfluorooctanoic acid induces anxiety-like behaviors by increasing corticotropin-releasing factor in the basolateral amygdala complex
6 Dec 2021 | Chemosphere
PFOA exposure in mice led to a metabolic cascade of effects resulting in anxiety-like behaviors.
Perfluorooctane sulfonate (PFOS) exposure of bovine oocytes affects early embryonic development at human-relevant levels in an in vitro model
6 Dec 2021 | Toxicology
Human-relevant levels of PFOS alter early bovine embryo development in vitro.