Exposure assessment of PFAS-contaminated sites using avian eggs as a biomonitoring tool: a frame of reference and a case study in the Po River valley (Northern Italy)

30 Mar 2021 | Integr Environ Assess Manag

PFOA and C6O4 were found in three species of wild passerines at unprecedented levels.

Per- and polyfluoroalkyl substances (PFASs) in Swedish household dust and exposure of pet cats

29 Mar 2021 | Environ Sci Pollut Res Int

Dust was found to be a relevant exposure pathway for the ingestion of some PFAS for cats, and the serum levels of PFAS could be of relevance for the cat's health.

Per- and polyfluoroalkyl mixtures toxicity assessment "Proof-of-Concept" illustration for the hazard index approach

25 Mar 2021 | J Toxicol Environ Health A

Hazard index scores were used as an initial assessment of multiple health effects of fluorinated mixtures.

Suspect Screening, Prioritization, and Confirmation of Environmental Chemicals in Maternal-Newborn Pairs from San Francisco

24 Mar 2021 | Environ Sci Technol

Methyl perfluoroundecanoate and 2-perfluorooctyl ethanoic acid were found in newborns during a critical development period.

Prenatal exposure to mixtures of persistent endocrine-disrupting chemicals and birth size in a population-based cohort of British girls

24 Mar 2021 | Epidemiology

PFAS was determined to be the most important contributor to the association with decreased birth weight.

Fate and transport of per- and polyfluoroalkyl substances (PFASs) in the vadose zone

23 Mar 2021 | Sci Total Environ

In this review, we critically discuss the current state of the knowledge and aim to interconnect the complex processes that control the fate and transport of PFASs in groundwater.

Characterization of an AFFF impacted freshwater environment using total fluorine, extractable organofluorine and suspect per- and polyfluoroalkyl substance screening analysis

23 Mar 2021 | Chemosphere

A tool was developed to close the organofluorine mass balance and to tentatively identify overlooked PFASs in various water sources.

Plasma Concentrations of Per- and Polyfluoroalkyl Substances and Body Composition from Mid-childhood to Early Adolescence

23 Mar 2021 | J Clin Endocrinol Metab

Early-life exposure to some but not all PFAS may be associated with adverse changes in body fat levels.

Sediment quality assessment framework for per- and polyfluoroalkyl substances: results from a preparatory study and REGULATORY IMPLICATIONS

23 Mar 2021 | Integr Environ Assess Manag

PFOS is a suitable indicator of PFAS contamination in sediments from small streams, being the most detected and on average with the highest concentrations among the analyzed PFAS in Switzerland.

N-acetyl cysteine co-treatment abates perfluorooctanoic acid-induced reproductive toxicity in male rats

23 Mar 2021 | Andrologia

N-acetylcysteine suppressed inflammatory responses and remedied PFOA-mediated reproductive injuries in rats.

Development of a Gestational and Lactational Physiologically Based Pharmacokinetic (PBPK) Model for Perfluorooctane Sulfonate (PFOS) in Rats and Humans and Its Implications in the Derivation of Health-Based Toxicity Values

23 Mar 2021 | Environ Health Perspect

This study provides a quantitative tool to aid risk reevaluation of PFOS, especially in sensitive human subpopulations, and it provides a basis for extrapolating to other PFAS.

Perfluorooctanoic acid-induced immunotoxicity via NF-kappa B pathway in zebrafish (Danio rerio) kidney

23 Mar 2021 | Fish Shellfish Immunol

This study expands the understanding of PFOA-induced immunosuppression and suggests that toxicity mechanisms should be considered for further health risk assessment of emerging pollutants.

Occurrence and fate of legacy and novel per- and polyfluoroalkyl substances (PFASs) in freshwater after an industrial fire of unknown chemical stockpiles

23 Mar 2021 | Environ Pollut

Acute high dose exposure to PFASs can result from industrial fires at sites storing or stockpiling PFAS-based waste products.

PFOS dominates PFAS composition in ambient fine particulate matter (PM) collected across North Carolina nearly 20 years after the end of its US production

22 Mar 2021 | Environ Sci Process Impacts

This is the first US study to provide insights into ambient PFAS concentrations in PM2.5.