Perfluorooctane sulfonate alternatives and metabolic syndrome in adults: New evidence from the Isomers of C8 Health Project in China
20 Apr 2021 | Environ Pollut
Exposure to Cl-PFESAs was associated with a cluster of conditions that occur together, increasing the risk of heart disease, stroke, and type 2 diabetes.
Lipid responses to environmental perfluoroalkyl substance exposure in a Taiwanese Child cohort
20 Apr 2021 | Environ Pollut
Different lipid patterns were discovered in children exposed to different levels of specific PFASs, such as PFTrDA, PFOS, and PFDA.
Assessing Indoor Dust Interference with Human Nuclear Hormone Receptors in Cell-Based Luciferase Reporter Assays
19 Apr 2021 | Environ Health Perspect
PFAS was found to exhibit hormonal activities in humans from indoor dust.
Long-term leaching of PFAS from contaminated agricultural soils in Germany
19 Apr 2021 | J. Contam. Hydrol.
Analysis of field data over a time period of 12 years revealed no or slowly decreasing trends as well as seasonal fluctuations, likely due to the ongoing transformation of precursors and a seasonal influence on production rates of mobile PFAS.
Fluorine-Specific Detection Using ICP-MS Helps to Identify PFAS Degradation Products in Nontargeted Analysis
19 Apr 2021 | Anal Chem
The feasibility of the detection of PFAS metabolites using a fluorine-specific detection was demonstrated using a model compound and can thus be applied to new experiments and unknown organofluorine-containing samples in the future.
Toxicological Response of Chironomus dilutus in Single Chemical and Binary Mixture Exposure Experiments with Six Perfluoralkyl Substances
13 Apr 2021 | Environ Toxicol Chem
PFOS was found to be the most toxic PFAS to aquatic life and suggests that PFOS could be more toxic to freshwater insects than previously reported.
Joint effects of prenatal exposure to per- and poly-fluoroalkyl substances and psychosocial stressors on corticotropin-releasing hormone during pregnancy
13 Apr 2021 | J Expo Sci Environ Epidemiol
PFAS was associated with higher levels of stress hormones which affected joints in pregnant women.
Per- and polyfluoroalkyl Substances (PFAS) as Contaminants of Emerging Concern in Asia's Freshwater Resources
13 Apr 2021 | Environ Res
The highest PFAS contamination was detected in surface water relative to ground, tap, and drinking water.
Occurrence and sources of per- and polyfluoroalkyl substances in the ice-melting lakes of Larsemann Hills, East Antarctica
13 Apr 2021 | Sci Total Environ
In the ice-melting lakes, PFOA, PFOS, and Cl-PFESA were detected in ice-melt lakes on the eastern side of Antarctica where there are fewer on-site human activities.
In-Vitro and In-Silico Assessment of Per- and Polyfluoroalkyl Substances (PFAS) in Aqueous Film-Forming Foam (AFFF) Binding to Human Serum Albumin
13 Apr 2021 | Toxics
Carboxylic acid and sulfonic acid-containing PFAS were found to bioaccumulate the most readily in human blood.
Time Trend of Persistent Organic Pollutants and Metals in Greenlandic Inuit during 1994-2015
13 Apr 2021 | Int J Environ Res Public Health
PFOS, PFHxS, and PFOA decreased across Greenland while PFNA, PFDA, and PFUnDA increased in women.
Investigating Molecular Mechanisms of Immunotoxicity and the Utility of ToxCast for Immunotoxicity Screening of Chemicals Added to Food
13 Apr 2021 | Int J Environ Res Public Health
PFAS show weak or no activity in immune-related ToxCast assays, which differs from traditional toxicological studies.
Biological and behavioural responses of European honey bee (Apis mellifera) colonies to perfluorooctane sulfonate (PFOS) exposure
12 Apr 2021 | Integr Environ Assess Manag
PFOS exposure adversely affects honey bee colonies and may transfer to honey.
The interplay between environmental exposures and COVID-19 risks in the health of children
7 Apr 2021 | Env. Health
An international group of researchers interested in children’s environmental health was invited to identify knowledge gaps and to develop research questions to close these gaps.
Considerations for Toxicity Experiments and Risk Assessments with PFAS Mixtures
7 Apr 2021 | IEAM
This perspective article discusses available approaches for mixtures risk assessment with a specific focus on application to PFAS mixtures.