Showing 1-15 of 287
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Sex specificity in associations between exposure to a mixture of per and poly-fluoroalkyl substances and anxiety among US adults
Science
7 Jan 2025 | J Expo Sci Environ Epidemiol
Exposure to mixtures of PFAS was linked to anxiety in U.S. adults, with males showing decreased anxiety and females showing increased anxiety, highlighting sex-specific effects.
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Per-and polyfluoroalkyl substances in paired serum and breastmilk samples among pregnant farmworkers in Thailand
Science
16 Dec 2024 | Int. J. Hyg. Environ. Health.
PFOS and PFNA were the most commonly detected PFAS in breastmilk from Thai farmworkers, with lactational transfer efficiencies up to 14.7%, highlighting a significant route of postnatal exposure for infants.
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Individual and joint associations of exposure to per- and polyfluoroalkyl substances with children's mitochondrial DNA copy number, and modified by estimated glomerular filtration rate
Science
10 Dec 2024 | Environ Res
Legacy and emerging PFAS, especially PFOA, were associated with lower levels of mitochondrial DNA in children, with more pronounced associations seen in those with weaker kidney function and older age, highlighting the potential health risks of PFAS exposure in early life.
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Associations between per-and polyfluoroalkyl substances and menstrual cycle regularity in reproductive-aged female: a cross-sectional study
Science
25 Nov 2024 | Emerging Contaminants
Exposure to branched PFOS and PFNA was significantly associated with irregular and long menstrual cycles, with these effects being more pronounced among women with low physical activity, suggesting potential reproductive risks linked to PFAS exposure and the influence of lifestyle factors.
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The Exposure Status of Environmental Chemicals in South Korea: The Korean National Environmental Health Survey 2018-2020
Science
19 Nov 2024 | Toxics
Among Korean adolescents, PFAS such as PFOA, PFOS, PFNA, and PFDeA were correlated with higher cholesterol levels, including LDL-C and total cholesterol. Adolescents highly exposed to both PFAS and heavy metals like mercury also had significantly higher lipid profiles.
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Serum per- and polyfluoroalkyl substance (PFAS) levels and health-related biomarkers in a pilot study of skiers in New England
Science
8 Oct 2024 | Environ Res
Ski coaches were found to have elevated levels of PFAS through ski wax exposure as well as higher cholesterol levels, suggesting a need for interventions to reduce PFAS in ski waxes and limit environmental release.
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Assessment of per- and poly-fluoroalkyl substances and physiological biomarkers in aquarium-based bottlenose dolphins and killer whales
Science
6 Aug 2024 | Chemosphere
PFAS, especially PFOS and PFNA, were found in the serum of zoo-based bottlenose dolphins and killer whales, and the study revealed significant correlations between PFAS exposure and physiological effects, such as increased reactive oxygen species, suggesting potential health risks that could inform future conservation and regulatory decisions.
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Association between mixed exposure to per-and polyfluoroalkyl substances and metabolic syndrome in Korean adults: Data from the Korean National environmental health survey cycle 4
Science
1 Aug 2024 | Int. J. Hyg. Environ. Health
Exposure to multiple PFAS increases the risk of metabolic syndrome—a cluster of conditions including obesity, high blood pressure, high triglycerides, low HDL cholesterol, and high blood sugar—particularly in females, with significant contributions from PFNA.
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Examining the Impact of Polyfluoroalkyl Substance Exposure on Erythrocyte Profiles and Its Related Nutrients: Insights from a Prospective Study on Young Taiwanese
Science
29 Jul 2024 | Environ. Pollut.
A decade-long study of 502 young Taiwanese individuals found that PFAS exposure is associated with changes in erythrograms, linking specific PFAS compounds to increased transferrin saturation and decreased vitamin B12 levels, with significant interactions involving iron status, vitamin B12, and folate.
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Associations between prenatal exposure to per- and polyfluoroalkyl substances and plasma immune molecules in three-year-old children in China
Science
27 Jul 2024 | Toxicol Appl Pharmacol
Prenatal exposure to PFAS significantly affects immune molecule levels in three-year-old children, with specific PFAS linked to increases in interleukins and Eotaxin-3, which help regulate the immune system, highlighting the need to understand environmental impacts on early immune development.
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Prenatal Exposure of PFAS in Cohorts of Pregnant Women: Identifying the Critical Windows of Vulnerability and Health Implications
Science
25 Jul 2024 | Environ. Sci. Technol.
From 2018 to 2020, a prenatal PFAS exposure study in pregnant women and their newborns showed a decline in older PFAS but an increase in emerging PFAS and highlighted the third trimester as a critical window affecting birth weight and length.
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Occurrence of 80 Per and polyfluorinated alkyl substances (PFAS) in the Muscle and Liver tissues of Marine Mammals of the St. Lawrence Estuary and Gulf, Quebec, Canada
Science
10 Jun 2024 | Front. Environ. Chem.
Marine mammals from the St. Lawrence Estuary and Gulf, such as dolphins and porpoises, were found to have high levels of PFAS in their tissues, with the white-sided dolphin showing the highest average concentrations—39 ng/g in muscle and 334 ng/g in liver—while species like the harp seal had much lower levels, emphasizing the need for stronger regulations to protect these vulnerable animals.
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Association of co-exposure to organophosphate esters and per- and polyfluoroalkyl substances and mixture with cardiovascular-kidney-liver-metabolic biomarkers among Chinese adults
Science
4 Jun 2024 | Ecotoxicol Environ Saf
Exposure to common environmental contaminants like organophosphate esters and PFAS, especially PFHxS and PFNA, is associated with disruptions in liver function and cholesterol levels, suggesting potential risks for chronic diseases due to their widespread presence in the human body.
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Per- and polyfluoroalkyl substances (PFAS) and fetal growth: A nation-wide register-based study on PFAS in drinking water
Science
8 May 2024 | Environ Int
A nationwide study in Sweden found no clear link between maternal exposure to certain PFAS during pregnancy and newborn birthweight or risk of being small-for-gestational-age, but did find a slight increase in the risk of being large-for-gestational-age, particularly associated with PFOS.
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Associations between serum perfluoroalkyl and polyfluoroalkyl concentrations and diabetes mellitus in the Korean general population: Insights from the Korean National Environmental Health Survey 2018-2020
Science
26 Apr 2024 | Int J Hyg Environ Health
PFAS exposure and prediabetes risk in the general Korean population was found to have a significant positive association between specific PFAS compounds, such as PFHxS and PFOS, and the risk of pre-diagnostic diabetes and prediabetes.