Showing 1-15 of 272
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[Press Release] EPA Announces Key Step to Advance Science, Better Protect Communities from PFAS Pollution
Policy
25 Oct 2022
In October 2021, the US EPA issued a final human health toxicity assessment for GenX chemicals, a processing aid technology used to make high-performance fluoropolymers without the use of PFOA.
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Demographic, life-style and physiological determinants of serum per- and polyfluoroalkyl substance (PFAS) concentrations in a national cross-sectional survey of Swedish adolescents
Science
17 Jan 2022 | Environ Res
Legacy PFAS were found at elevated levels throughout Swedish adolescents in addition to the novel 9Cl-PF3ONS in 5% of those tested, and females had lower serum PFAS concentration than males.
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Exposure to perfluorooctanoic acid leads to promotion of pancreatic cancer
Science
16 Jan 2022 | Carcinogenesis
PFOA was found to potentially promote pancreatic cancer progression in a mice model.
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Quantitation of linear and branched perfluoroalkane sulfonic acids (PFSAs) in women and infants during pregnancy and lactation
Science
10 Jan 2022 | Environ Int
A linear relation between PFSA concentrations in mothers at pregnancy week 18 and infants at six months was observed, suggesting that pregnancy and lactation are major excretion routes for PFSA, but accumulate in the infant.
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Characterization of Per- and Polyfluorinated Alkyl Substances Present in Commercial Anti-fog Products and Their Adipogenic Activity
Science
10 Jan 2022 | Environ Sci Technol
High concentrations of PFAS were detected in all measured anti-fog products, with FTEOs found to be a significant contributor to the adipogenic activity exhibited by the anti-fog sprays.
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US EPA turns down requests for more PFAS toxicity testing
Policy
30 Dec 2021
The US EPA has deferred or turned down advocacy groups’ requests to require Chemours to conduct toxicity tests on dozens of fluorochemicals found in North Carolina drinking water supplies.
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Environmental pollutant exposure associated with altered early-life gut microbiome: Results from a birth cohort study
Science
20 Dec 2021 | Environ Res
Prenatal exposure to PFAS is associated with alterations to gut microbiome development in infants, with larger effects in breastfed and cesarean-section-born babies.
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The comprehensive analysis based study of perfluorinated compounds-Environmental explanation of bladder cancer progression
Science
20 Dec 2021 | Ecotoxicol Environ Saf
PFAS could promote bladder cancer progression.
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Association between maternal serum concentration of perfluoroalkyl substances (PFASs) at delivery and acute infectious diseases in infancy
Science
20 Dec 2021 | Chemosphere
Prenatal exposure to PFAS was associated with increased risks of diarrhea during the first year of life, and these effects were stronger among breastfed infants.
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Relationships between maternal perfluoroalkyl substance levels, polymorphisms of receptor genes, and adverse birth outcomes in the Hokkaido birth cohort study, Japan
Science
20 Dec 2021 | Reprod Toxicol
Maternal PFOS exposure was linked with decreased female infant size.
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The use of in vitro methods in assessing human health risks associated with short-chain perfluoroalkyl and polyfluoroalkyl substances (PFAS)
Science
13 Dec 2021 | J Appl Toxicol
This review summarizes the PFAS toxicity data obtained using human cells in vitro, discusses the advantages and limitations of cell-based models, and provides thoughts on potential solutions to the challenges of these methods.
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Life-Time Environmental Chemical Exposure and Obesity: Review of Epidemiological Studies Using Human Biomonitoring Methods
Science
13 Dec 2021 | Front Endocrinol (Lausanne)
A review of chemical exposure and obesity found that PFOA has consistent obesogenic effects in humans.
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Maternal consumption of ultra-processed foods and newborn exposure to perfluoroalkyl substances (PFAS)
Science
13 Dec 2021 | Cad Saude Publica
Infants were found to have higher levels of PFAS if their mothers ate processed foods at least three times a week.
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Perfluorooctane sulfonate induces heart toxicity involving cardiac apoptosis and inflammation in rats
Science
6 Dec 2021 | Exp Ther Med
Exposure to PFOS left rats with heart inflammation and other markers of cardiac toxicity.
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Tumorigenic activity of alternative per- and polyfluoroalkyl substances (PFAS): Mechanistic in vitro studies
Science
6 Dec 2021 | Sci Total Environ
PFHxS has been associated with breast cancer in epidemiological studies, and this study demonstrated how this shorter-chain PFAS can affect cell proteins and cell proliferation.