Showing 1-15 of 197
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Thyroid Disruptors: Extrathyroidal Sites of Chemical Action and Neurodevelopmental Outcome-an Examination Using Triclosan and Perfluorohexane Sulfonate (PFHxS)
Science
21 Jul 2021 | Toxicol Sci
Lifelong exposure to PFAS could affect both the thyroid hormone status and the immune defense of perch in the wild.
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Chronic low-level perfluorooctane sulfonate (PFOS) exposure promotes testicular steroidogenesis through enhanced histone acetylation
Science
20 Jul 2021 | Environ Pollut
Low-level PFOS exposure was found to promote the development of steroid hormones.
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Exposure to perfluorooctane sulfonate in vitro perturbs the quality of porcine oocytes via induction of apoptosis
Science
20 Jul 2021 | Environ Pollut
PFOS exposure leads to decreased reproductive success by decreasing viable sperm count.
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Why is elevation of serum cholesterol associated with exposure to perfluoroalkyl substances (PFAS) in humans? A workshop report on potential mechanisms
Science
19 Jul 2021 | Toxicology
In this report, we summarize the relevant background data, the discussion among the attendees, and their recommendations for further research.
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Varied thyroid disrupting effects of perfluorooctanoic acid (PFOA) and its novel alternatives hexafluoropropylene-oxide-dimer-acid (GenX) and ammonium 4,8-dioxa-3H-perfluorononanoate (ADONA) in vitro
Science
13 Jul 2021 | Environ Int
GenX was found to disrupt the thyroid to a greater extent than PFOA and ADONA.
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A long road to recovery for Lake Superior fish
News
12 Jul 2021 | Environmental Health News
The Jackfish Bay white sucker population has nearly recovered, but persistent chemicals remain a problem throughout the Great Lakes.
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Perfluorooctanoic acid induces liver and serum dyslipidemia in humanized PPARα mice fed an American diet.
Science
9 Jul 2021 | Toxicol Appl Pharmacol
Diet was found to possibly influence PFAS’s liver toxicity.
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Maternal exposure to perfluoroalkyl chemicals and anogenital distance in the offspring: a Faroese cohort study
Science
6 Jul 2021 | Reprod Toxicol
Elevated maternal exposure to major PFAS was significantly associated with a longer anogenital distance in boys.
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Prospective associations of mid-childhood plasma per- and polyfluoroalkyl substances and pubertal timing
Science
6 Jul 2021 | Environ Int
Higher PFAS plasma concentrations in mid-childhood were associated with the later onset of puberty in girls.
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Per- and Polyfluoroalkyl Substances (PFAS) and Hormone Levels during the Menopausal Transition
Science
6 Jul 2021 | J Clin Endocrinol Metab
PFAS was found to affect reproductive aging through stimulating follicle hormones and estradiol levels in midlife women during the menopausal transition.
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Effects of gestational exposures to chemical mixtures on birth weight using Bayesian factor analysis in the Health Outcome and Measures of Environment (HOME) Study
Science
29 Jun 2021 | Environ Epidemiol
PFAS exposure was linked to lower birth weights.
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Exposure to isomers of per- and polyfluoroalkyl substances increases the risk of diabetes and impairs glucose-homeostasis in Chinese adults: Isomers of C8 health project
Science
23 Jun 2021 | Chemosphere
Chronic exposure to PFAS isomers was associated with impaired glucose levels and may increase the prevalence of type-2 diabetes in Chinese adults.
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Differential susceptibility of rat primary neurons and neural stem cells to PFOS and PFOA toxicity
Science
16 Jun 2021 | Toxicol Lett
The PFAS-induced alterations in neurons observed in rodents may also impact development and brain disease.
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Associations of perfluoroalkyl and polyfluoroalkyl substances (PFAS) and PFAS mixtures with adipokines in midlife women
Science
9 Jun 2021 | Int J Hyg Environ Health
Some PFAS may alter circulating levels of leptin, affecting the ‘hunger’ sensation.
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Perfluorotridecanoic Acid Inhibits Leydig Cell Maturation in Male Rats in Late Puberty via Changing Testicular Lipid Component
Science
9 Jun 2021 | Chem Res Toxicol
PFTrDA delays the maturation of testicle cells in late puberty mainly by altering the free fatty acid profile.