Showing 16-30 of 312
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Associations of dietary intake and longitudinal measures of per- and polyfluoroalkyl substances (PFAS) in predominantly Hispanic young Adults: A multicohort study
Science
27 Jan 2024 | Environ Int
Dietary factors, such as tea & pork intake and eating food not prepared at home, were associated with increases in blood levels of PFAS in young Hispanic adults, underscoring the significance of diet in PFAS exposure and the need for monitoring food and beverage contamination.
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Toxicity Assessment of Mixed Exposure of Nine Perfluoroalkyl Substances at Concentrations Relevant to Daily Intake
Science
10 Jan 2024 | Toxics
This study exposed mice to a mixture of PFAS at levels equivalent to estimated daily human intake, revealing that even low concentrations of PFAS caused liver tissue changes and altered gene expression related to metabolism and cancer, emphasizing the need for thorough toxicity assessments of these persistent environmental contaminants.
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Association of prenatal exposure to perfluorinated and polyfluoroalkyl substances with childhood neurodevelopment: A systematic review and meta-analysis
Science
10 Jan 2024 | Ecotoxicol Environ Saf
A meta-analysis on prenatal exposure to PFAS suggests a sex-specific relationship, revealing that PFOS, PFOA, and PFHxS are associated with decreased performance IQ in boys but PFOS was linked to increased performance IQ in girls, while PFAS are linked to executive function impairments in children without a significant association with behavioral difficulties.
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Understanding the effects of per- and polyfluoroalkyl substances on early skin development: Role of ciliogenesis inhibition and altered microtubule dynamics
Science
30 Dec 2023 | Sci Total Environ
Exposure to PFOS may disrupt early skin development by altering cell morphology, gene expression, and crucial signaling pathways, suggesting a potential link between PFAS exposure and congenital skin diseases during embryonic development.
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Occurrence of Major Perfluorinated Alkylate Substances in Human Blood and Target Organs
Science
28 Dec 2023 | Environ Sci Technol
PFAS levels in the liver correlated well with other organs, supporting the use of blood concentrations as a measure of PFAS exposure and suggesting the liver as the primary organ of PFAS retention, with minor variations observed in other organs.
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Per-and poly-fluoroalkyl substances (PFAS) exposure is associated with later occurrence of inflammatory bowel disease
Science
27 Dec 2023 | CGH
A connection was found between elevated PFAS levels and increased odds of Crohn’s disease and ulcerative colitis for up to 10 years prior to diagnosis, with both legacy and emerging PFAS chemicals implicated.
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Associations of a Prenatal Serum Per- and Polyfluoroalkyl Substance Mixture with the Cord Serum Metabolome in the HOME Study
Science
13 Dec 2023 | Environ Sci Technol
Prenatal exposure to a mixture of PFAS in mothers is linked to alterations in infant metabolic pathways, which can result in birthweight or vaccine response abnormalities.
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Association between probiotic consumption and serum perfluoroalkyl and polyfluoroalkyl substances (PFAS): results from NHANES, 2003–2018
Science
28 Nov 2023 | Environ. Sci. Eur.
The consumption of probiotics through yogurt or supplements is associated with lower levels of certain PFAS, suggesting potential health benefits.
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Per- and poly-fluoroalkyl substances in commercial organic eggs via fishmeal in feed
Science
7 Nov 2023 | Chemosphere
Organic eggs from certain farms in Denmark were found to contain elevated levels of PFAS originating from fishmeal used in organic feed, leading to the voluntary removal of fishmeal from the feed by producers to mitigate PFAS exposure.
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Chemical crisis: The unseen toxic threat contaminating wildlife worldwide
News
28 Oct 2023 | The Hill
An unseen but growing chemical contamination crisis is threatening wildlife across all seven continents, exacerbating a host of environmental threats they’re already facing.
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Trends in Serum Per-and Polyfluoroalkyl Substance (PFAS) Concentrations in Teenagers and Adults, 1999–2018 NHANES
Science
27 Oct 2023 | Int. J. Environ. Res. Public Health
Some longer chain PFAS levels in serum have decreased over time, however they are still detected in drinking water and consumer products, with certain racial/ethnic groups showing differing levels of exposure, highlighting the need for continued monitoring.
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Per- and Polyfluoroalkyl Substances (PFAS) in PubChem: 7 Million and Growing
Science
23 Oct 2023 | Environ. Sci. Technol.
The Organisation for Economic Co-operation and Development's 2021 revision of the PFAS definition has led to the inclusion of over 7 million PFAS compounds in PubChem.
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An integrated assessment of ecological and human health risks of per- and polyfluoroalkyl substances through toxicity prediction approaches
Science
18 Sep 2023 | Sci Total Environ
PFOS and PFOA are the most prevalent PFAS in surface water and in humans, and modeling indicates that they result in endocrine disruption and multi-generational behavioral effects.
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Per-and polyfluoroalkyl substances, gestational weight gain, postpartum weight retention and body composition in the UPSIDE cohort
Science
11 Sep 2023 | Environmental Health
PFOA and PFHxS exposure during pregnancy are associated with altered patterns of gestational weight gain and post-partum adiposity with potential implications for fetal development and long-term maternal cardiometabolic health.
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Per- and polyfluoroalkyl substances and sleep health in U.S. adults, NHANES 2005-2014
Science
6 Sep 2023 | Environ Res
No indications were found that exposure to four legacy PFAS compounds has a detrimental impact on the self-reported sleep quality of U.S. adults.