Showing 16-30 of 363
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Association between prenatal exposure to per-and polyfluoroalkyl substances and pubertal development in boys and girls in the Spanish INMA cohort
Science
26 Feb 2026 | Environ Res
Prenatal exposure to PFHxS, PFOS, PFOA, and PFNA may be associated with changes in the timing of puberty, with PFHxS linked to earlier adrenal maturation in girls and PFOS showing mixed patterns across sexes, supporting concerns that PFAS may influence endocrine pathways during development.
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Per-and polyfluoroalkyl substances (PFAS) and menstrual cycle characteristics in midlife women: The Study of Women’s Health Across the Nation
Science
26 Feb 2026 | Reprod Toxicol
Higher serum concentrations of several PFAS, including PFOS, PFOA, PFNA, and PFHxS, were associated with greater variability in menstrual cycle length and shorter or lighter menstrual bleeding among midlife women.
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Diet and everyday product use and serum per-and polyfluoroalkyl substances levels in the Korean population: Findings from the Korean national environmental health survey
Science
23 Feb 2026 | Environ. Res.
Higher serum PFAS levels were most strongly associated with seafood intake, especially fish and shellfish, and with use of food contact materials such as disposable paper cups, plastic pouches, and coated cookware, while a distinct pattern suggested PFHxS may be more closely linked to fast food consumption and personal care or household products.
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Validation of the U.S. Food and Drug Administration's Method for Detection of Per- and Polyfluoroalkyl Substances Analytes in Food and Feed: First Action 2025.06
Science
3 Feb 2026 | J AOAC Int
The U.S. FDA method was found to reliably measure 30 PFAS, such as PFOS, PFOA, PFNA, and PFHxS, across a range of human and animal foods.
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An integrated in vitro and in silico testing strategy applied to PFAS inhibition of antibody production to define a tolerable daily intake
Science
3 Jan 2026 | Toxicol Lett
PFOS, PFOA, PFNA, and PFHxS, may inhibit antibody production, with modeled human-equivalent effect doses that are similar to or lower than existing European Food Safety Authority health-based guidance values.
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Serum perfluoroalkyl and polyfluoroalkyl substances and the risk of cardiometabolic diseases: Unraveling the mediating role of inflammatory markers
Science
24 Dec 2025 | Eco Environ Health
Combined exposure to several PFAS was associated with increased risk of cardiometabolic conditions, particularly abnormal blood lipids and high blood pressure, with specific PFAS such as PFHxS, PFNA, and PFTrDA emerging as potential key contributors.
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Mediating role of proteomics in the association between per-and polyfluoroalkyl substance exposure and blood pressure in youth
Science
15 Dec 2025 | Environ Pollut.
PFOA, PFNA, PFOS, PFHxS, and PFHpS, exposure may be associated with higher blood pressure in youth through protein changes (particularly galectin-3) involving inflammatory and scarred tissue.
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Assessing the impact of perfluoroalkyl substances on liver health: A comprehensive study using multi-donor human liver spheroids
Science
8 Dec 2025 | Environ. Int.
PFHxS, PFOA, PFOS, and PFNA may interfere with liver function in different ways depending on the specific chemical and the sex of the donor cells, potentially contributing to fat buildup in the liver, weakened immune activity, and molecular changes linked to cancer development.
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Associations between PFAS in public water system drinking water and serum among Southern California adults
Science
30 Oct 2025 | J Expo Sci Environ Epidemiol
PFAS contamination in drinking water may be a significant contributor to adult serum PFAS levels, even among communities without high level contamination from industrial manufacturing.
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Association between maternal exposure to per-and polyfluoroalkyl substances and childhood growth trajectories up to 4 years of age: The Japan environment and children’s study
Science
24 Oct 2025 | Environ Sci Technol
Maternal exposure to PFAS during pregnancy was linked to slower early childhood growth in Japan, with higher PFOS, PFOA, and PFHxS levels associated with lower weight gain and shorter height through age four, suggesting that prenatal PFAS exposure may hinder fetal and postnatal development.
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Concentrations of per-and polyfluoroalkyl substances (PFAS) in private well drinking water and serum of individuals exposed to PFAS through biosolids: The Maine Biosolids Study
Science
20 Oct 2025 | Environ. Pollut.
Individuals living near farmland where PFAS-contaminated biosolids were historically applied had elevated PFAS in their private well water and blood, especially PFOA, which showed a strong water-to-serum correlation, demonstrating that biosolids can be a major exposure source and that some people may still have high serum levels even when their current water meets standards.
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Changes in the levels and predictors of per-and poly-fluoroalkyl substances in maternal plasma, relative to timelines of EPA PFOA Stewardship
Science
18 Oct 2025 | Environ. Int.
PFOS, PFOA, PFHxS, PFHpS, and Me-PFOSA-AcOH declined over time after EPA’s PFOA Stewardship Program, but other PFAS such as PFNA, PFUnA, PFDeA, PFDoA, and GenX increased especially among non-White mothers, and higher levels were linked to eating fish/shellfish and vegetables, working, and having carpet or pets during pregnancy, showing that policies reduced some PFAS but exposure sources and inequities remain.
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PFAS in stormwater control measures: Removal, distribution, and long-term fate
Science
18 Oct 2025 | Water Research
Stormwater systems such as ponds and filters are not designed to remove PFAS, so most PFAS pass through the system, build up in water and sediment over time, and can transform from precursors into more toxic terminal PFAS, making stormwater a growing and often hidden source of PFAS pollution in the environment.
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Association between perfluoroalkyl and polyfluoroalkyl substances exposure and hypercholesterolemia among US adults: A cross-sectional study
Science
25 Aug 2025 | Ecotoxicol Environ Saf.
Analysis of NHANES 2015–2018 data (n = 2,292) showed that higher serum levels of PFHxS, PFOA, and PFOS were significantly associated with increased prevalence of hypercholesterolemia, with PFHxS as the strongest contributor in mixture models, while combined PFAS exposure consistently elevated risk across multiple statistical approaches.
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PFAS Exposure and Postoperative Weight Regain in Adolescents After Bariatric Surgery: Findings From the Teen-LABS Study
Science
14 Aug 2025 | Obesity (Silver Spring)
Adolescents with higher pre-surgery blood levels of certain PFAS chemicals were more likely to regain weight and waist size in the years after bariatric surgery, potentially reducing the procedure’s long-term health benefits.