Showing 496-510 of 529
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Serum concentrations of perfluoroalkyl substances and their association with osteoporosis in a population in Jeddah, Saudi Arabia
Science
11 Jun 2020 | Environ. Res.
Exposure to PFOA, PFOS, PFNA, PFHxS, and PFUnDA was associated with osteoporosis in a sample of the adult Saudi population.
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Does Low Maternal Exposure to Per- and Polyfluoroalkyl Substances Elevate the Risk of Spontaneous Preterm Birth? A Nested Case-Control Study in China
Science
8 Jun 2020 | Environ. Sci. Technol.
Maternal exposure to the determined low levels of PFAS may lead to inflammation and possible developmental effects in fetuses and newborns.
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Study finds PFAS exposure may cause early menopause in women
News
3 Jun 2020 | Endocrine Society
Per- and polyfluoroalkyl substance (PFAS) exposure may cause menopause to occur two years earlier in women, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.
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Perfluoroalkyl Substance Exposure Was Negatively Associated With Cortisone Levels in Pregnancy
Science
19 May 2020 | J Endocr Soc
Early pregnancy concentrations of maternal PFAS were inversely associated with late pregnancy cortisone levels, indicating potential endocrine disruption in highly exposed mothers.
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Adverse effects of in vitro GenX exposure on rat thyroid cell viability, DNA integrity and thyroid-related genes expression.
Science
19 May 2020 | Environ. Pollut.
GenX exposure is associated with endocrine disruption by damaging the thyroid cell's DNA.
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Associations of Per-/Polyfluoroalkyl Substances with Glucocorticoids and Progestogens in Newborns
Science
12 May 2020 | Env. Int.
These results suggested that not only PFOS and PFOA but also other PFAS have potential impacts on the endocrine system in newborns.
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Perfluoroalkyl and polyfluroalkyl substances and maternal thyroid hormones in early pregnancy
Science
12 May 2020 | Environ. Pollut.
Several long-chain PFAS were associated with disrupted thyroid hormones in Chinese pregnant women.
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Endocrine-disrupting chemicals weaken us in our COVID-19 battle
News
23 Apr 2020 | Environmental Health News
We are an unhealthy nation—and many of our elevated disease rates are linked to environmental chemicals. COVID-19 is bringing into sharp focus the need to prevent this widespread exposure.
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Prenatal exposure to per- and polyfluoroalkyl substances and maternal and neonatal thyroid function in the Project Viva Cohort: A mixtures approach
Science
21 Apr 2020 | Environ Int
Prenatal exposure to multiple PFAS was associated with abnormal maternal and neonatal thyroid function.
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Toxicokinetics and persistent thyroid hormone disrupting effects of chronic developmental exposure to chlorinated polyfluorinated ether sulfonate in Chinese rare minnow
Science
7 Apr 2020 | Environ. Poll.
Thyroid hormones and gene regulation remained at disturbed levels in adult fish, due to PFAS exposure.
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Metabolic and Pharmaceutical Aspects of Fluorinated Compounds
Science
24 Mar 2020 | J of Medi. Chem.
A review of the literature associated with the metabolism of fluorinated molecules, focusing on examples where the presence of fluorine influences the metabolic profile.
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Interaction between hypoxia and perfluorobutane sulfonate on developmental toxicity and endocrine disruption in marine medaka embryos
Science
17 Mar 2020 | Aq. Tox.
PFBS found to disrupt development and the endocrine system of juvenile fish.
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Assessment of the Mode of Action Underlying the Effects of GenX in Mouse Liver and Implications for Assessing Human Health Risks
Science
11 Mar 2020 | Toxicol Pathol
GenX found to change liver function through interruption of receptors such as PPARα.
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Perfluoroalkyl Substances Stimulate Insulin Secretion by Islet β Cells via G Protein-Coupled Receptor 40
Science
3 Mar 2020 | Environ. Sci. Technol.
Evidence for a novel mechanism for how PFASs disrupt insulin-secretion in a human was discovered.
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Per- and Polyfluoroalkyl Substances: An Emerging Contaminant of Concern
Science
2 Mar 2020 | Ann. Rev. of Nur. Res.
This chapter discusses the health harm associated with PFAS, exposure and risk reduction, advisory levels, and medical testing/management.