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• Changes in perfluoroalkyl substances (PFAS) concentrations in human milk over the course of lactation: A study in Ronneby mother-child cohort

  Science

  15 Dec 2022 | Environ Res

  PFOA concentrations in breast milk decreased over the course of lactation by 12% per month, while PFOS and PFHxS showed small changes.

• Cross-sectional associations of maternal PFAS exposure on SARS-CoV-2 IgG antibody levels during pregnancy

  Science

  14 Dec 2022 | Environ Res

  PFAS, including short-chain emerging PFAS, act as immunosuppressants during pregnancy.

• Emerging Contaminants and New POPs (PFAS and HBCDD) in Endangered Southern Resident and Bigg’s (Transient) Killer Whales (Orcinus orca): In Utero Maternal Transfer and Pollution Management Implications

  Science

  13 Dec 2022 | ACS

  7:3-fluorotelomer carboxylic acid was the primary PFAS detected in killer whales' skeletal muscle and liver samples in the Northeastern Pacific Ocean, followed by PFOS, PFOA, and PFHxS.

• Human serum poly- and perfluoroalkyl substance concentrations and their associations with gestational diabetes mellitus

  Science

  6 Dec 2022 | Environ Pollut

  Higher serum PFAS concentrations were associated with gestational diabetes incidence in pregnant women, especially for PFOA, PFNA, PFHxS, and 6:2 Cl-PFESA.

• Bayesian Estimation of Human Population Toxicokinetics of PFOA, PFOS, PFHxS, and PFNA from Studies of Contaminated Drinking Water

  Science

  1 Dec 2022 | Environ Health Perspect

  A harmonized methodology was developed to determine the half-life and volume of distribution for PFOA, PFOS, PFNA, and PFHxS.

• The effects of perfluoroalkyl and polyfluoroalkyl substances on female fertility: A systematic review and meta-analysis

  Science

  2 Nov 2022 | Environ Res

  Increased levels of PFAS exposure are associated with reduced female fertility, which should be taken into account for risk assessments of manufacturing products containing PFAS.

• Plasma concentrations of perfluoroalkyl acids and their determinants in youth and adults from Nunavik, Canada

  Science

  14 Oct 2022 | Chemosphere

  Long-chain PFAAs levels were 4–7 fold higher in Nunavik Inuit adults compared to the Canadian population and were associated with hunting activity, omega-3 fatty acids, and drinking water from environmental sources.

• Maternal Exposure to Per- and Polyfluoroalkyl Substances (PFAS) and Male Reproductive Function in Young Adulthood: Combined Exposure to Seven PFAS

  Science

  5 Oct 2022 | Environ Health Perspect

  Consistent inverse associations between exposure to maternal PFAS and semen quality were found in a sample of the Danish population.

• Emerging contaminants migration from pipes used in drinking water distribution systems: a review of the scientific literature

  Science

  20 Sep 2022 | Environ Sci Pollut Res Int

  PFOA, PFNA, PFDA, PFOS, and PFHxS were detected at levels indicating a potential non-carcinogenic health risk to consumers.

• First report on per- and polyfluoroalkyl substances (PFASs) in coral communities from the Northern South China sea: Occurrence, seasonal variation, and interspecies differences

  Science

  20 Sep 2022 | Environ Pollut

  PFHxS accounted for 43% of total PFAS detected in corals with short-chain PFAS concentrations higher than legacy PFAS, though concentrations depended on seasonal factors and coral type.

• Perfluoroalkyl and polyfluoroalkyl substances (PFASs) crossing the blood-cerebrospinal fluid barrier: Their occurrence in human cerebrospinal fluid

  Science

  15 Sep 2022 | J Hazard Mater

  New and legacy PFAS were found cerebrospinal fluid at levels lower than in blood, though levels were higher in the elderly compared with other age groups.

• Associations of perfluoroalkyl and polyfluoroalkyl substances with gestational hypertension and blood pressure during pregnancy: A cohort study

  Science

  8 Sep 2022 | Environ Res

  Higher concentrations of PFAS during early pregnancy were associated with lower gestational hypertension risk and reduced blood pressure measures in the third trimester in a population with relatively high exposure levels.

• Association between fish oil supplements use and serum per- and polyfluoroalkyl substances (PFAS): Results from the National Health and Nutrition Examination Survey

  Science

  29 Aug 2022 | Environ Res

  Fish oil supplement consumers did not have increased serum PFAS levels, specifically, but some inverse associations observed between the supplement use and PFOS levels in older adults and females need further study.

• Food Grown on Fire Stations as a Potential Pathway for Firefighters’ Exposure to Per-and Poly-Fluoroalkyl Substances (PFAS)

  Science

  15 Aug 2022 | Environ. Int.

  Firefighters may be most exposed to PFAS by consuming food grown on fire stations, followed by incidental ingestion and dermal absorption of PFAS in dust.

• Outside the Safe Operating Space of a New Planetary Boundary for Per-and Polyfluoroalkyl Substances (PFAS)

  Science

  2 Aug 2022 | ES&T

  PFAS have been detected at unsafe levels in rain globally, leading to the conclusions that the spread of PFOS, PFOA, PFHxS, and PFNA in the atmosphere has exceeded levels of concern for chemical pollution and that PFAS uses and emissions should be rapidly restricted.