Showing 421-435 of 518
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Associations between six common per- and polyfluoroalkyl substances and estrogens in neonates of China.
Science
10 Nov 2020 | J Hazard Mater
This study provided epidemiological data on the associations between common PFAS exposures resulting in hormone disruption in newborns.
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Exposure to perfluorobutane sulfonate and perfluorooctanesulfonic acid disrupts the production of angiogenesis factors and stress responses in human placental syncytiotrophoblasts
Science
10 Nov 2020 | Reprod Toxicol
Exposure to PFOS or PFBS impacts several key pathways associated with preeclampsia.
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Exposure to Perfluorooctanoic Acid Induces Cognitive Deficits via Altering Gut Microbiota Composition, Impairing Intestinal Barrier Integrity, and Causing Inflammation in Gut and Brain
Science
10 Nov 2020 | J Agric Food Chem
PFOA exposure has potentially harmful immflamatory effects on the gut and brain.
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Severity of COVID-19 at elevated exposure to perfluorinated alkylates
Science
9 Nov 2020 | medRxiv
Elevated plasma-PFBA concentrations were associated with an increased risk of a more severe course of COVID-19
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PFAS concentration during pregnancy in relation to cardiometabolic health and birth outcomes
Science
20 Oct 2020 | Environ Res
PFAS was found ubiquitously in American pregnant women with PFNA being associated with pre-term birth.
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Perfluoroalkyl acids in pregnant women from Nunavik (Quebec, Canada): Trends in exposure and associations with country foods consumption
Science
20 Oct 2020 | Environ Int
The exposure of pregnant women to long-chain PFAAs (PFNA, PFDA, and PFUdA) increased from 2004 to 2017, potentially through a diet high in fish.
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Effect of perfluorohexane sulfonate on pig oocyte maturation, gap-junctional intercellular communication, mitochondrial membrane potential and DNA damage in cumulus cells in vitro
Science
20 Oct 2020 | Toxicol In Vitro
Exposure to PFHxS induced DNA damage in immature egg cells.
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Endocrine disruption of vitamin D activity by perfluoro-octanoic acid (PFOA)
Science
14 Oct 2020 | Sci Rep
PFOA exposure was found to be associated with vitamin D deficiency and potentially weakening bones.
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Per- and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research
Science
13 Oct 2020 | Environ Toxicol Chem
The goals of this review are to assess the state of the science regarding the toxicological effects of PFAS, and to develop strategies for advancing knowledge on the health effects of this large family of chemicals.
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Are Fluoropolymers Really of Low Concern for Human and Environmental Health and Separate from Other PFAS?
Science
12 Oct 2020 | ES&T
Given fluoropolymers’ extreme persistence; emissions associated with their production, use, and disposal; and a high likelihood for human exposure to PFAS, their production and uses should be curtailed except in cases of essential uses.
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Perfluorooctanesulfonic acid (PFOS) and perfluorohexanesulfonic acid (PFHxS) alter the blood lipidome and the hepatic proteome in a murine model of diet-induced obesity.
Science
7 Oct 2020 | Toxicol. Sci.
PFOS and PFHxS were found to increase the risk of metabolic and inflammatory disease when a diet high in fat was consumed.
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Associations between serum concentrations of perfluoroalkyl substances and DNA methylation in women exposed through drinking water: A pilot study in Ronneby, Sweden.
Science
6 Oct 2020 | Env. Int.
Women exposed to PFAS contaminated water were found to likely be at risk of hormone disruption and cancer due to altered DNA methylation.
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Perfluorooctane sulfonic acid (PFOS) exposure during Pregnancy Increases Blood Pressure and Impairs Vascular Relaxation Mechanisms in the Adult Offspring
Science
6 Oct 2020 | Reprod. Toxicol.
PFOS exposure during prenatal life caused low birth weight followed by catch-up growth only in females and lead to hypertension and altered muscle performance in both males and females.
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Effects of perfluoroalkyl carboxylic acids on the uptake of sulfobromophthalein via organic anion transporting polypeptides in human intestinal Caco-2Â cells.
Science
29 Sep 2020 | Biochem Biophys Rep
PFHpA, PFOA, PFNA, PFDA, and PFUnDA, significantly decreased the ability to take up and move hormones in human cells.
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Perfluorooctanoic acid (PFOA) inhibits the gap junction intercellular communication and induces apoptosis in human ovarian granulosa cells
Science
29 Sep 2020 | Reprod. Toxicol.
PFOA was associated with endocrine disruption causing cell death in human ovarian cells.