Showing 61-75 of 250
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Maternal exposure to perfluoroalkyl chemicals and anogenital distance in the offspring: a Faroese cohort study
Science
6 Jul 2021 | Reprod Toxicol
Elevated maternal exposure to major PFAS was significantly associated with a longer anogenital distance in boys.
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Per- and Polyfluoroalkyl Substances (PFAS) and Hormone Levels during the Menopausal Transition
Science
6 Jul 2021 | J Clin Endocrinol Metab
PFAS was found to affect reproductive aging through stimulating follicle hormones and estradiol levels in midlife women during the menopausal transition.
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Prospective associations of mid-childhood plasma per- and polyfluoroalkyl substances and pubertal timing
Science
6 Jul 2021 | Environ Int
Higher PFAS plasma concentrations in mid-childhood were associated with the later onset of puberty in girls.
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Effects of gestational exposures to chemical mixtures on birth weight using Bayesian factor analysis in the Health Outcome and Measures of Environment (HOME) Study
Science
29 Jun 2021 | Environ Epidemiol
PFAS exposure was linked to lower birth weights.
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Exposure to isomers of per- and polyfluoroalkyl substances increases the risk of diabetes and impairs glucose-homeostasis in Chinese adults: Isomers of C8 health project
Science
23 Jun 2021 | Chemosphere
Chronic exposure to PFAS isomers was associated with impaired glucose levels and may increase the prevalence of type-2 diabetes in Chinese adults.
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Differential susceptibility of rat primary neurons and neural stem cells to PFOS and PFOA toxicity
Science
16 Jun 2021 | Toxicol Lett
The PFAS-induced alterations in neurons observed in rodents may also impact development and brain disease.
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Perfluorotridecanoic Acid Inhibits Leydig Cell Maturation in Male Rats in Late Puberty via Changing Testicular Lipid Component
Science
9 Jun 2021 | Chem Res Toxicol
PFTrDA delays the maturation of testicle cells in late puberty mainly by altering the free fatty acid profile.
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Associations of perfluoroalkyl and polyfluoroalkyl substances (PFAS) and PFAS mixtures with adipokines in midlife women
Science
9 Jun 2021 | Int J Hyg Environ Health
Some PFAS may alter circulating levels of leptin, affecting the ‘hunger’ sensation.
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Early-life associations between per- and polyfluoroalkyl substances and serum lipids in a longitudinal birth cohort
Science
8 Jun 2021 | Environ Res
Childhood PFAS exposures may be associated with elevated serum lipid concentrations which can be a predictor of later development of hyperlipidemia and cardiovascular disease.
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Exploration of the developmental toxicity of TCS and PFOS to zebrafish embryos by whole-genome gene expression analyses
Science
1 Jun 2021 | Environ Sci Pollut Res Int
PFOS was found to disrupt normal organ development compared to triclosan.
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Perfluoroalkyl substance pollutants activate the innate immune system through the AIM2 inflammasome
Science
25 May 2021 | Nat Commun
The AIM2 receptor in mice was found to reduce PFOS-induced inflammation, as well as tissue damage in the lungs, livers, and kidneys.
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Evaluating the potential of KOH-modified composite biochar amendment to alleviate the ecotoxicity of perfluorooctanoic acid-contaminated sediment on Bellamya aeruginosa.
Science
25 May 2021 | Ecotoxicol Environ Saf
Both individual and combined PFAS could induce concentration-dependent cell toxicity and depletion of glutathione levels.
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Risk Assessment of Perfluorooctane Sulfonate (PFOS) using Dynamic Age Dependent Physiologically based Pharmacokinetic Model (PBPK) across human lifetime
Science
25 May 2021 | Environ Res
A model was developed to quantify the risk of PFOS throughout the human lifetime, particularly in susceptible age groups.
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Perfluoroalkyl and polyfluoroalkyl substances and body size and composition trajectories in midlife women: the study of women's health across the nation 1999-2018
Science
19 May 2021 | Int J Obes (Lond)
Certain PFAS were positively associated with greater body size and body fat and may be an underappreciated contributing factor to obesity risk.
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Maternal exposure of mice to sodium p-perfluorous nonenoxybenzene sulfonate causes endocrine disruption in both dams and offspring
Science
18 May 2021 | Endocr J
Exposure to PFAS was associated with endocrine disruption in mothers and their offspring.