Showing 16-30 of 1016
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Occurrence, bioaccumulation and trophic dynamics of per- and polyfluoroalkyl substances in two tropical freshwater lakes
Science
14 Feb 2024 | Environ Pollut
PFAS were measured in different fish species in two lakes in Nigeria, identifying the presence of novel PFAS, diSAMPAP and 9CL-PF3ONS, and documenting the role of urbanization on PFAS in the environment for the first time in Africa.
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Associations of per- and polyfluoroalkyl substances with maternal metabolic and inflammatory biomarkers in early-to-mid-pregnancy
Science
10 Feb 2024 | Environ Res
Exposure to PFAS during early-to-mid pregnancy was associated with decreased insulin levels, increased HDL cholesterol, and alterations in inflammatory markers, suggesting potential metabolic and inflammatory disruptions that may impact maternal and fetal health.
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Perfluorooctanesulfonic acid (PFOS) disrupts cadherin-16 in the developing rat thyroid gland
Science
6 Feb 2024 | Curr Res Toxicol
PFOS exposure in rodents may disrupt thyroid hormone system development, potentially affecting growth and neurodevelopment, as evidenced by altered gene expression patterns in hormone levels and follicular integrity.
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Distribution and release of PFAS from AFFF-impacted asphalt: How does it compare to concrete?
Science
5 Feb 2024 | J. Hazard. Mater.
AFFF-impacted asphalt and concrete were found to potentially leach PFAS into the environment, with 6:2 FTS and PFOS identified as the dominant PFAS in the surface layer and runoff, asphalt exhibited a higher release rate compared to concrete.
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Association between Perfluoroalkyl Substances in Follicular Fluid and Polycystic Ovary Syndrome in Infertile Women
Science
26 Jan 2024 | MDPI
A clinical study revealed a positive relationship between PFOA levels in follicular fluid and increased odds of polycystic ovary syndrome, suggesting PFOA as a potential risk factor for this endocrine disease in women.
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Occurrence and pattern of legacy and emerging per-and Poly-FluoroAlkyl substances (PFAS) in eggs of loggerhead turtle Caretta caretta from western Mediterranean
Science
22 Jan 2024 | Environ. Pollut.
Many PFAS were found in loggerhead turtle eggs off the coast of Italy, including emerging PFAS, and the highest concentrations in some eggs may be due to fluoropolymer-based marine litter that turtles may ingest.
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Maternal serum concentrations of per- and polyfluoroalkyl substances and childhood acute lymphoblastic leukemia
Science
13 Jan 2024 | JNCI
Maternal exposure to certain PFAS during pregnancy, particularly MeFOSAA, is associated with an increased risk of childhood acute lymphoblastic leukemia, with notable connections to elevated levels of PFOS, suggesting a potential link between these environmental chemicals and the development of the most common childhood cancer.
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Association of prenatal exposure to perfluorinated and polyfluoroalkyl substances with childhood neurodevelopment: A systematic review and meta-analysis
Science
10 Jan 2024 | Ecotoxicol Environ Saf
A meta-analysis on prenatal exposure to PFAS suggests a sex-specific relationship, revealing that PFOS, PFOA, and PFHxS are associated with decreased performance IQ in boys but PFOS was linked to increased performance IQ in girls, while PFAS are linked to executive function impairments in children without a significant association with behavioral difficulties.
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Toxicity Assessment of Mixed Exposure of Nine Perfluoroalkyl Substances at Concentrations Relevant to Daily Intake
Science
10 Jan 2024 | Toxics
This study exposed mice to a mixture of PFAS at levels equivalent to estimated daily human intake, revealing that even low concentrations of PFAS caused liver tissue changes and altered gene expression related to metabolism and cancer, emphasizing the need for thorough toxicity assessments of these persistent environmental contaminants.
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Assessing potential human health and ecological implications of PFAS from leave-in dental products
Science
3 Jan 2024 | Toxicol Ind Health
PFBA and PFOS were found in low levels in night guards with no detection in whitening trays, suggesting these dental products are unlikely to pose health concerns or contribute significantly to environmental PFAS exposure compared to exposure from food and water.
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Understanding the effects of per- and polyfluoroalkyl substances on early skin development: Role of ciliogenesis inhibition and altered microtubule dynamics
Science
30 Dec 2023 | Sci Total Environ
Exposure to PFOS may disrupt early skin development by altering cell morphology, gene expression, and crucial signaling pathways, suggesting a potential link between PFAS exposure and congenital skin diseases during embryonic development.
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Occurrence of Major Perfluorinated Alkylate Substances in Human Blood and Target Organs
Science
28 Dec 2023 | Environ Sci Technol
PFAS levels in the liver correlated well with other organs, supporting the use of blood concentrations as a measure of PFAS exposure and suggesting the liver as the primary organ of PFAS retention, with minor variations observed in other organs.
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Per-and poly-fluoroalkyl substances (PFAS) exposure is associated with later occurrence of inflammatory bowel disease
Science
27 Dec 2023 | CGH
A connection was found between elevated PFAS levels and increased odds of Crohn’s disease and ulcerative colitis for up to 10 years prior to diagnosis, with both legacy and emerging PFAS chemicals implicated.
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First insights into per-and polyfluoroalkyl substance contamination in edible fish species of the Indus water system of Pakistan
Science
17 Dec 2023 | Chemosphere
The study investigated the contamination of edible fish in major tributaries of the Indus System andfound high levels of PFAS, in certain fish species from areas with poor wastewater treatment in Pakistan, highlighting potential environmental and health concerns, and suggesting the need for ongoing monitoring and research into the bioaccumulation patterns of PFAS.
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Unregulated Active and Closed Textile Mills Represent a Significant Vector of PFAS Contamination into Coastal Rivers
Science
15 Dec 2023 | ACS ES&T Water
Sampling of rivers downstream from textile miles revealed higher concentrations of PFOS and PFCAs, demonstrating that both closed and active mills are important ongoing sources of PFAS to freshwater and marine regions.