Showing 1-15 of 335
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Association between perfluoroalkyl and polyfluoroalkyl substances exposure and hypercholesterolemia among US adults: A cross-sectional study
Science
25 Aug 2025 | Ecotoxicol Environ Saf.
Analysis of NHANES 2015–2018 data (n = 2,292) showed that higher serum levels of PFHxS, PFOA, and PFOS were significantly associated with increased prevalence of hypercholesterolemia, with PFHxS as the strongest contributor in mixture models, while combined PFAS exposure consistently elevated risk across multiple statistical approaches.
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PFAS Exposure and Postoperative Weight Regain in Adolescents After Bariatric Surgery: Findings From the Teen-LABS Study
Science
14 Aug 2025 | Obesity (Silver Spring)
Adolescents with higher pre-surgery blood levels of certain PFAS chemicals were more likely to regain weight and waist size in the years after bariatric surgery, potentially reducing the procedure’s long-term health benefits.
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Serum Levels of Per- and Polyfluoroalkyl Substances in Adults Aged 18 and Older in Relation to the Length of Residency in United States
Science
11 Aug 2025 | J Immigr Minor Health
Immigrants to the U.S. tend to have lower levels of PFAS such as PFOA, PFOS, PFHxS, PFNA, and PFDeA upon arrival, but their levels increase over time, often matching those of U.S.-born people within 5 to 15 years, depending on race, ethnicity, and differences in past and ongoing environmental exposures.
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PFAS in rural U.S. well water: Using participatory science to identify and communicate results to address risks
Science
7 Aug 2025 | Environ. Sci. Technol.
PFAS were found in rural U.S. private wells, most often PFOA, PFOS, and PFHxS, with some exceeding the U.S. EPA’s 2023 drinking water limits even in areas with no known sources.
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Levels of serum per- and polyfluoroalkyl substances and association with dyslipidemia in the Korean population
Science
7 Jul 2025 | Ecotoxicol Environ Saf
A large national study of nearly 3,000 Korean adults found widespread PFAS exposure and showed that higher serum concentrations of several compounds, especially PFOA, PFHxS, PFNA and PFDeA, were consistently associated with elevated low-density lipoprotein cholesterol and total cholesterol, implying potential cardiovascular risk and reinforcing the need for stricter regulation.
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Temporal changes in per and polyfluoroalkyl substances and their associations with type 2 diabetes
Science
1 Jul 2025 | Sci Rep
A 30-year Norwegian study found that blood levels of PFHpA, PFNA, PFHxS and PFHpS increased at a faster rate in people who later developed type 2 diabetes, indicating that exposure to these pollutants may play a role in the disease.
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Investigation of Perfluorooctanesulfonic Acid (PFOS) and Perfluorooctanoic Acid (PFOA) Isomer Profiles in Naturally Contaminated Food Samples
Science
25 Jun 2025 | J Agric Food Chem
Analysing PFOS- and PFOA-contaminated milk, deer meat, eggs and clams, FDA researchers found that calibrating with isomer-matched standards and quantifying branched and linear forms separately with a two-peak method decreased PFOS overestimation in branched-rich samples, while the distinctive isomer fingerprints traced some contamination to firefighting-foam runoff on dairy farms.
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Chrome Plating Facility Siting Is Associated with Neighborhood Demographic and Socioeconomic Factors and Elevated Per- and Polyfluoroalkyl Substances in Blood in California
Science
16 Jun 2025 | Environ Sci Technol
Residents living within 3 km of California chrome-plating shops showed markedly higher blood concentrations of specific plating-related PFAS—including PFOS, PFHxS, PFOA, PFHpS and PFPeS, underscoring how these mist-suppressant chemicals disproportionately burden nearby lower-income, largely Hispanic communities.
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Prenatal Per- and Polyfluoroalkyl Substance Exposures and Longitudinal Blood Pressure Measurements in Children Aged 3 to 18 Years: Findings From a Racially and Ethnically Diverse US Birth Cohort
Science
12 Jun 2025 | J Am Heart Assoc
Higher maternal blood levels of eight PFAS (Me-PFOSA-AcOH, PFDeA, PFHpS, PFHxS, PFNA, PFOA, PFOS and PFUnA) correlated with higher childhood blood-pressure readings, most noticeably during adolescence, in boys and in non-Hispanic Black youth, implying that prenatal exposure to these “forever chemicals” may increase long-term hypertension risk.
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Burden of per- and polyfluoroalkyl substances (PFAS) in human breast milk: Implications for maternal and infant health
Science
7 Jun 2025 | Environ Int
Analyzing pooled breast-milk samples from five UN regions, researchers estimate that up to 24 % of mothers and 17 % of babies already exceed plasma levels of PFHxS and PFNA linked to endocrine, immune and developmental harm.
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Per-and polyfluoroalkyl substances (PFAS) in placental compartments: Histopathological and toxicological data integration in an Italian cohort
Science
27 May 2025
Placenta samples from Italian pregnancies almost always contained multiple PFAS chemicals, and higher levels were tied to blood‑flow problems and abnormal growths, suggesting these persistent pollutants may disrupt normal placental function and threaten pregnancy health.
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Exposure to Legacy Per- and Polyfluoroalkyl Substances from Diet and Drinking Water in California Adults, 2018-2020
Science
14 May 2025 | Environ Sci Technol
This study characterized legacy PFAS in serum from 700 California adults and examined contributions from diet and drinking water concluding that drinking water remains an important source of exposure to PFOA and PFHxS in this population.
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Hair analysis as a non-invasive method for assessing the exposure of wildlife to per- and poly-fluoroalkyl substances (PFAS)
Science
13 May 2025 | Environ Pollut
By analyzing blood samples from 700 adults in southern and eastern California, scientists found that even low but detectable PFAS in local tap water significantly raised people’s levels of the legacy chemicals PFOA and PFHxS, while seafood and eggs contributed smaller amounts.
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Diet quality in relation to serum perfluoroalkyl substance concentrations in Canadian preadolescents
Science
6 May 2025 | Environ Res
In Canadian preadolescents, higher dietary intake of fat, fiber, and iron was associated with increased blood concentrations of several PFAS—especially PFOS, PFDA, and PFHxS—suggesting that most diets may contribute to PFAS exposure through contaminated food systems.
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Individual and mixtures of PFAS during pregnancy are associated with maternal cardiometabolic outcomes during pregnancy
Science
30 Apr 2025 | Environ Health
The majority of pregnant woman tested in central Arkansas had PFAS in her blood, and those with the highest levels showed shifts in cholesterol, triglycerides, resting pulse, and diastolic blood pressure— indicating potential harm to heart health during pregnancy.