Latest Science
Regrettable for whom? GenX chemicals as a case study in detrimental chemical substitution
18 Nov 2025 | Environ. Sci. Policy
The example of GenX’s substitution for PFOA shows how structural factors in the US chemical regulatory system, including data gaps, permissive loopholes, and limited oversight, can enable detrimental chemical replacement. These findings underscore the need for stronger policies that prioritize public health.
Asymmetrical contamination of anionic PFAS across global freshwater reservoirs
18 Nov 2025 | Water Research
Freshwater reservoirs across Asia, North America, Europe, Africa, and Oceania show three distinct PFAS contamination stages, including PFOA-dominated, PFOA plus PFOS co-dominated, and short-chain PFBA-dominated profiles, which together point to the need for more coordinated global multi-media PFAS monitoring and governance.
Development and evaluation of analytical strategies for the monitoring of per- and polyfluoroalkyl substances from lithium-ion battery recycling materials
11 Nov 2025 | Anal Bioanal Chem
The results of this study underline the threat of PFAS emissions from lithium-ion battery waste and recycling activities. Both legacy (PFSA and PFCA) and emerging PFAS were found, with levels of TFA found in every investigated material type.
PFAS-induced immunotoxicity in freshwater fish of inland China: mechanisms and ecological risks
10 Nov 2025 | Comp. Biochem. Physiol. C
PFAS are widespread in China’s freshwater systems, where long-chain and sulfonic types result in suppressed immune responses and higher infection risk. These effects worsen with co-exposure to heavy metals and microplastics.
Associations between per- and polyfluoroalkyl substances and reproductive outcomes among women undergoing in vitro fertilization/intracytoplasmic sperm injection treatment
10 Nov 2025 | Reprod Toxicol
Mixed exposure to long-chain PFAS and emerging chlorinated PFESAs in infertile Chinese women was associated with increased risk of infertility.
Per- and polyfluoroalkyl substances in municipal solid waste incineration ash: occurrence and management implications
9 Nov 2025 | Waste Manag
Municipal solid waste incineration ash from four Florida facilities contained measurable PFAS, with bottom ash showing higher levels dominated by diPAP precursors while fly ash held mostly short-chain PFAAs. These results highlight the need for stack and leaching tests as well as establishment of thresholds for some relevant PFAS to properly assess the risks of municipal solid waste incineration and ash reuse.
PFAS dynamics in the American black bear (Ursus americanus): Physiological stages (hyperphagia, hibernation, and post-hibernation), and temporal trends from 1989 to 2015
8 Nov 2025 | Sci Total Environ
PFAS built up in black bears during hibernation and declined after, with levels peaking around 2002 then dropping after PFOS phase-outs, while long-chain PFCAs kept rising, showing that newer PFAS continue to persist in the environment.
Potential health risks from contaminated fish in Lake Victoria: A 25-year systematic review of pollutants and management challenges
5 Nov 2025 | Sci Total Environ
The only reported PFAS levels in fish in Lake Victoria are from the northern part of the lake in Uganda, with measured levels below European safety thresholds. Lack of data from Kenyan or Tanzanian waters, indicates a geographic research gap.
F-53B exposure induced testicular premature aging through ZBP1-mediated programmed necrosis
4 Nov 2025 | J Hazard Mater
F-53B, a PFAS replacement for PFOS used in chrome plating, was found to cause severe reproductive toxicity, resulting in premature testicular aging in mice.
Concentrations of per- and polyfluoroalkyl substances in Canadian sea otters (Enhydra lutris) are higher near urban centers
4 Nov 2025 | Environ Toxicol Chem
PFAS were detected in all sampled British Columbia sea otters, with liver concentrations over 25 times higher than in muscle tissue and dominated by PFNA, PFOSA, and PFOS.
Childhood exposure to per-and polyfluoroalkyl substances during eating activities: Occurrence, exposure, and developmental risk
3 Nov 2025 | J. Environ. Chem. Ecotoxicol.
Children’s feeding bibs and tablecloths were found to contain multiple PFAS, including PFOA, PFNA, and PFOS. Modeled hand-to-mouth exposure during meals was estimated to approach or exceed safety thresholds for infants that potentially disrupt hormone and developmental pathways.
Associations between PFAS in public water system drinking water and serum among Southern California adults
30 Oct 2025 | J Expo Sci Environ Epidemiol
PFAS contamination in drinking water may be a significant contributor to adult serum PFAS levels, even among communities without high level contamination from industrial manufacturing.
Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) in seafood from Thailand: Levels, geographic distribution, and risk from dietary exposure
27 Oct 2025 | Environ Monit Assess
Short-chain PFAS like PFBS and PFPeA were the most common contaminants found in Thai rivers and irrigation canals, showing that industrial discharge, agriculture, and urban runoff are spreading these persistent chemicals even into areas once considered clean.
Historical blood serum samples from Wilmington, North Carolina: The importance of ultrashort-chain per- and polyfluoroalkyl Substances
27 Oct 2025 | Environ Sci Technol
This study adds to the body of evidence that ultrashort-chain PFAS occur in high levels in people. Two ultrashort-chain PFAS were detected at high levels in almost every sample.
Association between maternal exposure to per-and polyfluoroalkyl substances and childhood growth trajectories up to 4 years of age: The Japan environment and children’s study
24 Oct 2025 | Environ Sci Technol
Maternal exposure to PFAS during pregnancy was linked to slower early childhood growth in Japan, with higher PFOS, PFOA, and PFHxS levels associated with lower weight gain and shorter height through age four, suggesting that prenatal PFAS exposure may hinder fetal and postnatal development.