Latest Science

PFAS-induced immunotoxicity in freshwater fish of inland China: mechanisms and ecological risks

10 Nov 2025 | Comp. Biochem. Physiol. C

PFAS are widespread in China’s freshwater systems, where long-chain and sulfonic types result in suppressed immune responses and higher infection risk. These effects worsen with co-exposure to heavy metals and microplastics.

PFAS dynamics in the American black bear (Ursus americanus): Physiological stages (hyperphagia, hibernation, and post-hibernation), and temporal trends from 1989 to 2015

8 Nov 2025 | Sci Total Environ

PFAS built up in black bears during hibernation and declined after, with levels peaking around 2002 then dropping after PFOS phase-outs, while long-chain PFCAs kept rising, showing that newer PFAS continue to persist in the environment.

Potential health risks from contaminated fish in Lake Victoria: A 25-year systematic review of pollutants and management challenges

5 Nov 2025 | Sci Total Environ

The only reported PFAS levels in fish in Lake Victoria are from the northern part of the lake in Uganda, with measured levels below European safety thresholds. Lack of data from Kenyan or Tanzanian waters, indicates a geographic research gap.

F-53B exposure induced testicular premature aging through ZBP1-mediated programmed necrosis

4 Nov 2025 | J Hazard Mater

F-53B, a PFAS replacement for PFOS used in chrome plating, was found to cause severe reproductive toxicity, resulting in premature testicular aging in mice.

Concentrations of per- and polyfluoroalkyl substances in Canadian sea otters (Enhydra lutris) are higher near urban centers

4 Nov 2025 | Environ Toxicol Chem

PFAS were detected in all sampled British Columbia sea otters, with liver concentrations over 25 times higher than in muscle tissue and dominated by PFNA, PFOSA, and PFOS.

Childhood exposure to per-and polyfluoroalkyl substances during eating activities: Occurrence, exposure, and developmental risk

3 Nov 2025 | J. Environ. Chem. Ecotoxicol.

Children’s feeding bibs and tablecloths were found to contain multiple PFAS, including PFOA, PFNA, and PFOS. Modeled hand-to-mouth exposure during meals was estimated to approach or exceed safety thresholds for infants that potentially disrupt hormone and developmental pathways.

Associations between PFAS in public water system drinking water and serum among Southern California adults

30 Oct 2025 | J Expo Sci Environ Epidemiol

PFAS contamination in drinking water may be a significant contributor to adult serum PFAS levels, even among communities without high level contamination from industrial manufacturing.

Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) in seafood from Thailand: Levels, geographic distribution, and risk from dietary exposure

27 Oct 2025 | Environ Monit Assess

Short-chain PFAS like PFBS and PFPeA were the most common contaminants found in Thai rivers and irrigation canals, showing that industrial discharge, agriculture, and urban runoff are spreading these persistent chemicals even into areas once considered clean.

Historical blood serum samples from Wilmington, North Carolina: The importance of ultrashort-chain per- and polyfluoroalkyl Substances

27 Oct 2025 | Environ Sci Technol

This study adds to the body of evidence that ultrashort-chain PFAS occur in high levels in people. Two ultrashort-chain PFAS were detected at high levels in almost every sample.

Association between maternal exposure to per-and polyfluoroalkyl substances and childhood growth trajectories up to 4 years of age: The Japan environment and children’s study

24 Oct 2025 | Environ Sci Technol

Maternal exposure to PFAS during pregnancy was linked to slower early childhood growth in Japan, with higher PFOS, PFOA, and PFHxS levels associated with lower weight gain and shorter height through age four, suggesting that prenatal PFAS exposure may hinder fetal and postnatal development.

Challenging assumptions: Per-and polyfluoroalkyl substances detected in deep groundwater across southeastern Australia

22 Oct 2025 | ACS ES&T Water

PFAS compounds were detected in deep groundwater across southeastern Australia, including aquifers over 100 meters deep, revealing that even supposedly protected water sources are vulnerable to contamination through surface infiltration, bore leakage, and long-range subsurface transport.

Life cycle assessment and life cycle costing analysis for removing per-and polyfluoroalkyl substances from landfill leachate with foam fractionation Technology

22 Oct 2025 | ACS ES&T Water

Foam fractionation was identified as a sustainable and cost-effective method for removing PFAS from landfill leachate, cutting global warming potential by more than half compared to traditional one-stage systems and producing minimal hazardous waste, though energy use and short-chain PFAS removal remain challenges.

Bioaccumulation, bioamplification, and elimination behavior of per- and polyfluoroalkyl substances during insect metamorphosis: Different strategies for silkworms and locusts

22 Oct 2025 | J Hazard Mater

Silkworms and locusts respond to PFAS exposure in very different ways during metamorphosis: silkworms absorb more PFAS but eliminate up to 39% through molting and metamorphic changes, while locusts absorb less and mainly excrete PFAS through feces, revealing species-specific strategies for coping with environmental pollution and its effects on development.

Concentrations of per-and polyfluoroalkyl substances (PFAS) in private well drinking water and serum of individuals exposed to PFAS through biosolids: The Maine Biosolids Study

20 Oct 2025 | Environ. Pollut.

Individuals living near farmland where PFAS-contaminated biosolids were historically applied had elevated PFAS in their private well water and blood, especially PFOA, which showed a strong water-to-serum correlation, demonstrating that biosolids can be a major exposure source and that some people may still have high serum levels even when their current water meets standards.

Evaluating environmental health communication: The readability of factsheets about per-and polyfluoroalkyl substances (PFAS)

20 Oct 2025 | Int. J. Hyg. Environ. Health.

Most PFAS factsheets published by government agencies are written at a college reading level, use too much complex language, and rarely include visuals or clear summaries, making them hard for the public to understand and showing the need for simpler wording, better design, and use of communication tools to improve readability.

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