Latest Science

Residential proximity to transport facilities as urban determinants of individual-level per- and poly-fluoroalkyl substance (PFAS) exposures: Analysis of two longitudinal cohorts in Singapore

9 Jan 2026 | Environ Health

A longitudinal study of pregnant women in Singapore reports that residential proximity to large transport facilities, especially bus depots, is associated with higher blood levels of specific PFAS, notably PFBS, PFBA, and PFNA, highlighting a potentially important but largely unregulated urban exposure source linked to the widespread use of PFAS in automotive lubricants, hydraulic fluids, coatings, and other vehicle components.

Bioaccumulation of PFOS Isomers in Transporter Proteins

8 Jan 2026 | Chem Res Toxicol

Structural differences among PFOS isomers are associated with differing interactions with fatty acid transporter proteins, with some branched isomers potentially exhibiting comparable or greater bioaccumulation potential than linear PFOS based on combined in vitro uptake and molecular modeling results.

An integrated in vitro and in silico testing strategy applied to PFAS inhibition of antibody production to define a tolerable daily intake

3 Jan 2026 | Toxicol Lett

PFOS, PFOA, PFNA, and PFHxS, may inhibit antibody production, with modeled human-equivalent effect doses that are similar to or lower than existing European Food Safety Authority health-based guidance values.

Fate, bioaccumulation, and toxic responses of PFOA, PFOS, and GenX in the paddy soil-rice system across the full growth cycle

1 Jan 2026 | J Hazard Mater

Analysis of a full growth cycle study in paddy soil suggests that PFOA, PFOS, and the replacement PFAS GenX may disrupt rice growth and induce oxidative stress. GenX is showing greater upward movement into edible tissues, highlighting potential food-chain relevance and informing proposed soil safety thresholds for rice cultivation.

Unforeseen risks due to the use of fluorinated materials for per-and polyfluoroalkyl substance removal

30 Dec 2025 | Nature

Researchers report that fluorinated materials used for PFAS removal may inadvertently release additional fluorinated compounds during production, use, or disposal, suggesting that non-fluorinated alternatives offer safer options for treatment technologies.

A Componential Evaluation of Per- and Polyfluoroalkyl Substances (PFAS) in Municipal Solid Waste (MSW) Streams

30 Dec 2025 | Environ Sci Technol

PFAS were detected in every major waste component, with PFAS-treated textiles, which make up only about 9 percent of the waste stream, contributed roughly 38 percent of all leachable PFAS, identifying them as a dominant source of PFAS release from municipal solid waste from waste collected from Central Florida.

Per-and polyfluoroalkyl substances (PFASs) contamination and community impact: An interdisciplinary approach to teaching chemistry

29 Dec 2025 | Journal of Chemical Education

Students engaged in an interdisciplinary chemistry module were found to have an improved understanding of PFAS contamination and its ties to environmental inequity, suggesting that integrating socioscientific issues into core chemistry courses may better prepare students to navigate the ethical, cultural, and political dimensions of real world environmental challenges.

Developmental Toxicity of Photolithography-Relevant Per- and Polyfluoroalkyl Substances (PFAS) Reveals Concerns for Less-Studied Functional Groups

24 Dec 2025 | Environ Sci Technol

Several PFAS used in semiconductor manufacturing, including perfluoroalkyl dicarboxylic acids and perfluorosulfonamides, may cause developmental toxicity and disrupt lipid-metabolism genes in zebrafish at environmentally relevant levels, raising concerns for their continued use.

Gulls foraging in highly urbanized areas experience disruption in hormones and energetic metabolism

20 Dec 2025 | Environ Int

Urban-breeding ring-billed seagulls exposed to PFAS and halogenated flame retardants show sex-specific associations with thyroid hormones, corticosterone, and lipid metabolism markers, suggesting these chemicals may disrupt hormone regulation and energy metabolism.

Reevaluating PFAS exposure risks from marine fish

18 Dec 2025 | Science

A global modeling analysis finds that legacy PFAS exposure from marine fish may now be low for most countries due to production phaseouts, yet remains higher in places with very high seafood intake such as Greenland and Denmark, offering important insight for refining fish consumption guidance and noting where potential risk persists.

Formation of perfluorocarboxylic acids (PFCAs) from the incomplete thermal decomposition of perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA

16 Dec 2025 | ACS ES&T Air

PFOS and PFOA thermal treatment may consistently produce multiple perfluorocarboxylic acids and volatile fluorinated byproducts at suboptimal temperatures despite near-complete parent destruction, highlighting potential emissions concerns and uncertainties about the specific formation pathways.

Determination of analytical interferences for 4:2 fluorotelomer sulfonic acid in multiple agricultural matrices

16 Dec 2025 | J Agric Food Chem

Naturally occurring oxidized fatty acids in crops were found to generate the same mass-spectrometric signals as 4:2 FTS, which could lead to potentially inaccurate PFAS measurements in agricultural products and may warrant careful method evaluation before results are reported.

Childhood exposure to per-and polyfluoroalkyl substances in educational environments: Arising from stationery and implications for health

15 Dec 2025 | J. Environ. Chem. Ecotoxicol.

Several products purchased in China released measurable PFAS including precursors that increased after oxidation and maximum estimated intake from hand to mouth contact with some pen grips approaching the European Food Safety Authority tolerable intake for children.

Mediating role of proteomics in the association between per-and polyfluoroalkyl substance exposure and blood pressure in youth

15 Dec 2025 | Environ Pollut.

PFOA, PFNA, PFOS, PFHxS, and PFHpS, exposure may be associated with higher blood pressure in youth through protein changes (particularly galectin-3) involving inflammatory and scarred tissue.

A Dominating Role of Functional Groups in Short-Chain Per- and Polyfluoroalkyl Substance (PFAS) Accumulation by Fruiting Plants

11 Dec 2025 | Environ Sci Technol

Tomato plants were found to preferentially move short-chain PFAS with carboxylic acid groups into fruits while sulfonic acid PFAS are largely retained in roots and leaves, which could influence potential dietary exposure and guide crop choices in contaminated areas.

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