Exposure to perfluoroalkyl and polyfluoroalkyl substances and pediatric obesity: a systematic review and meta-analysis

31 Oct 2023 | Int J Obes (Lond)

The review investigated the potential impact of PFAS on childhood obesity. It observed a possible inverse relationship between postnatal PFAS exposure and changes in body mass index though the review was limited by the small number of studies.

Trends in Serum Per-and Polyfluoroalkyl Substance (PFAS) Concentrations in Teenagers and Adults, 1999–2018 NHANES

27 Oct 2023 | Int. J. Environ. Res. Public Health

Some longer chain PFAS levels in serum have decreased over time, however they are still detected in drinking water and consumer products, with certain racial/ethnic groups showing differing levels of exposure, highlighting the need for continued monitoring.

Is it raining PFAS in France? An analysis of 52 PFAS at ng/L levels in French rainwaters during Autumn season

27 Oct 2023 | J Environ Qual

This study analyzed rainwater in France for PFAS and detected the presence of PFNA, PFUnA, and PFHxA while also emphasizing the importance of environmental surveillance and improved analysis methods.

Environmental distribution of per-and polyfluoroalkyl substances (PFAS) on Svalbard: Local sources and long-range transport to the Arctic

23 Oct 2023 | Chemosphere

PFAS were found in various environmental samples along the west coast of the Norwegian Arctic with significant contributions from wastewater and a firefighting training site. Melting snow and ice during Arctic spring may also become an increasingly important PFAS source with climate warming.

Per- and Polyfluoroalkyl Substances (PFAS) in PubChem: 7 Million and Growing

23 Oct 2023 | Environ. Sci. Technol.

The Organisation for Economic Co-operation and Development's 2021 revision of the PFAS definition has led to the inclusion of over 7 million PFAS compounds in PubChem.

Dietary exposure to per- and polyfluoroalkyl substances: Potential health impacts on human liver

21 Oct 2023 | Sci Total Environ

PFAS contamination in food poses an especially elevated risk of liver toxicity to infants and adolescents and primarily comes from biomagnification through the food chain and food contact materials.

Perfluoroalkyl substances in umbilical cord blood and blood pressure in offspring: a prospective cohort study

19 Oct 2023 | Environmental Health

Exposure to certain long-chain PFAS, particularly PFOS, PFDA, and PFUA, in umbilical cord blood was associated with lower blood pressure in offspring at the age of 4 years, with PFUA being the most significant contributor and PFDoA exhibiting a positive association with blood pressure.

Metabolic Perturbations Associated with an Exposure Mixture of Per-and Polyfluoroalkyl Substances in the Atlanta African American Maternal-Child Cohort

19 Oct 2023 | Environ Sci Technol

Prenatal exposure to a mixture of PFAS chemicals, including PFOA, PFNA, PFOS, and PFHxS, is associated with significant metabolic perturbations indicative of systemic inflammation and oxidative stress in pregnant African-American women, highlighting the importance of considering the joint effects of these chemicals on human health.

Prenatal Exposure to Multiple Endocrine-Disrupting Chemicals and Childhood BMI Trajectories in the INMA Cohort Study

18 Oct 2023 | Environ Health Perspect

Exposure to HCB, DDE, PCBs, and PFNA was linked to an increased risk of lower birth size followed by accelerated BMI gain in single-exposure models.

Novel Insights into the Adverse Health Effects of per- and Polyfluoroalkyl Substances on the Kidney via Human Urine Metabolomics

18 Oct 2023 | Environ Sci Technol

Individuals with high occupational exposure to PFAS were found to have positive correlations with urinary PFAS levels to key small kidney molecules and to serum PFAS levels, suggesting that urine can be an indicator of the adverse effects of high PFAS exposure on kidney health and that urine PFAS levels can be a good indicator for serum levels.

Association of per- and polyfluoroalkyl substance exposure with metabolic syndrome and its components in adults and adolescents

16 Oct 2023 | Environ Sci Pollut Res Int

A population-based study found that PFAS were negatively associated with the prevalence of metabolic syndrome in both adults and adolescents, although there were conflicting findings across different components of this syndrome, indicating a complex relationship between PFAS exposure and metabolic health.

Environmental exposure to legacy and emerging per- and polyfluoroalkyl substances and endometriosis in women of childbearing age

14 Oct 2023 | Sci. Total Environ.

PFOA and certain PFOS isomers were positively associated with an increased risk of endometriosis.

Nontarget Screening Strategies for PFAS Prioritization and Identification by High Resolution Mass Spectrometry: A Review

14 Oct 2023 | Trends Environ. Anal. Chem.

Advanced analytical techniques, like non-target screening using high-resolution mass spectrometry, have been developed to identify different PFAS and address challenges due to the vast number and diversity of these compounds and the lack of standards. However, difficulties remain in identifying unknown PFAS in complex environmental samples.

Elevated Levels of Ultrashort- and Short-Chain Perfluoroalkyl Acids in US Homes and People

11 Oct 2023 | Environ Sci Technol

This study observed strong connections between the amounts of TFA, PFBA, and PFHpA in dust or water and their presence in the bloodstream, indicating that inhaling dust or drinking contaminated water are significant ways people are exposed to these short and ultra-short PFAS.

Kinetics and Mechanism of Ultrasonic Defluorination of Fluorotelomer Sulfonates

9 Oct 2023 | J. Phys. Chem. A

Ultrasound waves were found to effectively break down FTSAs of various sizes with the potential to degrade other PFAS.