Forever Chemicals (PFAS): An Overview for Maternity and Pediatric Health Care Professionals

1 Mar 2025 | MCN Am J Matern Child Nurs

Healthcare workers, especially those exposed to PFAS through medical supplies and occupational settings, face increased health risks, while pregnant individuals exposed to these chemicals may experience complications such as gestational hypertension, preeclampsia, and decreased birth weight in infants, highlighting the urgent need for monitoring and risk reduction strategies​.

Exposure to per‐and polyfluoroalkyl substances in residential settled dust and risk of childhood acute lymphoblastic leukemia

24 Feb 2025 | IJC

Exposure to a mixture of eight PFAS detected in household dust, particularly EtFOSAA, was associated with an increased risk of childhood acute lymphoblastic leukemia, highlighting residential dust as a potential source of PFAS exposure linked to cancer risk.

Sand dollars (Mellita quinquiesperforata): A new bioindicator for tracking PFAS in coastal waters

24 Feb 2025 | Mar. Pollut. Bull.

Sand dollars were found to serve as reliable indicators of PFAS pollution in coastal sediments, as they bioaccumulate these harmful chemicals, with the highest concentrations detected near pollution sources like MacDill Air Force Base and Albert Whitted Airport in Tampa Bay, Florida.

Bioaccumulation and transfer of legacy and emerging per-and polyfluoroalkyl substances throughout the lifecycle of a tropical amphibian species Fejervarya limnocharis

21 Feb 2025 | Environ. Sci. Technol.

PFAS were detected throughout the lifecycle of the tropical frogs Fejervarya limnocharis, with high concentrations in eggs that decreased in tadpoles and remained stable in juvenile and adult frogs, while specific PFAS with low tendency to bind to proteins showed greater accumulation in tadpoles, suggesting different bioaccumulation patterns influenced by developmental stage and exposure pathways​.

Screening estimates of bioaccumulation factors for 4950 per- and polyfluoroalkyl substances in aquatic species

20 Feb 2025 | J Hazard Mater

A machine learning model predicted bioaccumulation factors (BAFs) for 4,950 PFAS in 54 global edible fish species, revealing that PFAS with multiple functional groups tend to accumulate more, freshwater fish generally have higher BAFs than marine fish. An online tool was developed to support environmental risk assessment and policy decisions.

Association between PFAS exposure and metabolic-related biomarkers in Spanish adolescents

18 Feb 2025 | Environ Res

Exposure to PFAS chemicals in Spanish teenage boys was linked to higher blood sugar, cholesterol, and blood pressure, and the combination of different PFAS types affected liver health, with a hormone called kisspeptin possibly playing a role.

Minimizing the use of per-and polyfluoroalkyl substances for textured wetting-resistant surfaces.

17 Feb 2025 | Environ. Sci. Technol.

Textured surfaces made with materials, like polydimethylsiloxane and springtail-inspired structures, were found to have water- and oil-repellent properties similar to those of PFAS, offering alternatives for applications like water purification and self-cleaning textiles.

The stubborn “chemical invader”: Challenges and solutions for per-and polyfluoroalkyl substances (PFAS) in Chinese sewage sludge

17 Feb 2025 | ACS EST Water

Sewage sludge in China acts as both a source and sink for PFAS, with compounds like PFOS accumulating due to limited degradation by conventional wastewater treatments, highlighting the need for innovative extraction, detection, and environmentally sustainable removal methods to reduce associated environmental contamination and health risks.

Holistic assessment of chemical and biological pollutants in a mediterranean wastewater effluent-dominated stream: Interactions and ecological impacts

12 Feb 2025 | Environ. Pollut.

PFAS were detected in wastewater effluent on the Onyar River, in the northeast Spain, with PFOS showing the highest PFAS concentrations. PFPeA was the only PFAS detected downstream but not upstream, suggesting that its primary source was wastewater.

Number of Carbons Is a Critical Parameter for Accumulation of Per- and Polyfluoroalkyl Substances in the Human Brain

10 Feb 2025 | Environ Sci Technol

Longer-chain PFAS accumulate more in the human brain than shorter-chain PFAS, indicating that carbon chain length plays a crucial role in their distribution and raising concerns about potential neurological effects​.

Per‐and polyfluoroalkyl substances in untreated and treated sludge/biosolids from 27 water resource recovery facilities across the United States and Canada

9 Feb 2025 | Water Environ Res.

PFAS were detected in untreated and treated sludge biosolids from 27 water resource recovery facilities across the U.S. and Canada, with post-stabilized biosolids generally showing higher concentrations than pre-stabilized sludge, particularly for 5:3 FTCA and PFOS.

Maternal per- and polyfluoroalkyl substance concentrations and placental DNA methylation of thyroid hormone-related genes

8 Feb 2025 | J Hazard Mater

Exposure to PFAS during pregnancy may alter how certain genes in the placenta function, potentially affecting thyroid hormones in the developing baby and raising concerns about impacts on growth and health.

Surface soil PFAS mixtures dominated by PFOS: Prioritization for ecotoxicity testing and ecological risk assessment at current and former US Air Force Bases

7 Feb 2025 | Environ Toxicol Chem

PFAS mixtures in soil were dominated by PFOS (approximately 82%) but also included 5% to 12% of PFHxS, PFOA, PFOSA, and PFHxA. Additionally the study identified high concentrations but inconsistent prevalence of the 6:2 and 8:2 fluorotelomer sulfonates. These results highlight the need for toxicity testing of mixtures dominated by PFOS but including combinations of other PFAS.

Investigation of common and unreported parabens alongside other plastic-related contaminants in human milk using non-targeted strategies

6 Feb 2025 | Chemosphere

A study of human milk in Canada and South Africa detected multiple paraben-related contaminants, including restricted and uncommon ones, as well as a tire-related chemical, PFAS, and phthalate metabolites. The results emphasize the need to utilize non-target analysis as well as further research the usage, biotransformation, and potential toxicity of a number of contaminants.

[Report] Notes from the Field: Serum Concentrations of Perfluoroalkyl and Polyfluoroalkyl Substances Among First Responders to the Maui Wildfires - Hawaii, September 2023

6 Feb 2025 | MMWR Morb Mortal Wkly Rep

First responders to the 2023 Maui wildfires had elevated serum levels of PFAS, particularly firefighters, likely due to exposure from fire effluents, contaminated gear, and firefighting foams, raising concerns about long-term health risks such as cancer and metabolic disorders.