Sub-acute exposure of male guppies (Poecilia reticulata) to environmentally relevant concentrations of PFOA and GenX induces significant changes in the testis transcriptome and reproductive traits

26 Apr 2024 | Environ Int

Exposure of male guppies to environmentally realistic levels of a legacy PFAS and its replacement compound (GenX) resulted in altered reproductive traits, including changes in sexual behavior and sperm motility, as well as gene expression related to immune regulation. These changes highlight the potential adverse effects of PFAS on behavior, fertility, and immunity in fish populations.

Characterization of Per- and Polyfluoroalkyl Substances (PFAS) and Other Constituents in MSW Landfill Leachate from Puerto Rico

25 Apr 2024 | Chemosphere

Puerto Rico was found to have significantly elevated levels of PFAS in landfill leachate, with 51 PFAS detected above quantitation limits, including previously unreported compounds, indicating a potential risk to island environments and emphasizing the need for informed solid waste management decisions to mitigate PFAS contamination, especially in light of extreme climate events and drinking water contamination.

Quantifying Disparities in Per- and Polyfluoroalkyl Substances (PFAS) Levels in Drinking Water from Overburdened Communities in New Jersey, 2019-2021

24 Apr 2024 | Environ Health Perspect

63% of New Jersey's community water systems (serving 84% of the population) tested from 2019 to 2021 had PFAS detections, with overburdened communities more likely to have detections and exposure surpassing state maximum contaminant levels, and a higher proportion of people of color living in affected areas compared to non-Hispanic white populations.

[Perspective] Per- and Polyfluoroalkyl Substances in Drinking Water-Disparities in Community Exposures Based on Race and Socioeconomic Status

24 Apr 2024 | Environ Health Perspect

Systematic testing and public engagement, especially in rural and private well-dependent communities, are essential to addressing PFAS exposure data gaps and fully assessing disparities in exposures and health risk.

Nationwide distribution of perfluoroalkyl ether carboxylic acids in Chinese diets: An emerging concern

22 Apr 2024 | Environment International

PFECAs, particularly HFPO-DA, were found in high concentrations in Chinese diet samples, with estimated daily intake levels nearing or exceeding safety benchmarks set by the US EPA, especially in cereals.

PFAS in Nigeria: Identifying data gaps that hinder assessments of ecotoxicological and human health impacts

21 Apr 2024 | Heliyon

This review examines the impact of PFAS in Nigeria, highlighting their persistence and health risks, and recommends strengthening regulations and increasing collaborative research and education for improved management and healthier communities.

Partitioning of PFAS to serum, tissues, eggs, and hatchlings of an Australian freshwater turtle

15 Apr 2024 | J. Hazard. Mater.

Higher levels of certain PFAS were discovered in male turtles compared to females, with PFOS being the most prevalent in the turtles' tissues, while PFHxA was predominant in the surrounding water. All of the long chain PFAS were transferred from yolk to hatchling, suggesting an intergenerational effect.

Associations of per-and polyfluoroalkyl substances (PFAS) and their mixture with risk of rheumatoid arthritis in the US adult population

13 Apr 2024 | Environmental Health

Exposure to certain PFAS chemicals is associated with a reduced risk of rheumatoid arthritis, especially in females, according to a study analyzing data from over 10,000 adults.

In-Vitro Effects of Perfluorooctanoic Acid on Human Sperm Function: What Are the Clinical Consequences?

11 Apr 2024 | J. Clin. Med.

Exposure to PFOA in-vitro reduces sperm motility and damages sperm quality, suggesting a possible negative impact on male fertility.

Association of Combined Per-and Polyfluoroalkyl Substances and Metals with Chronic Kidney Disease

11 Apr 2024 | IJERPH

Exposure to PFAS and metals like cadmium and mercury is associated with chronic kidney disease, with cadmium showing a consistent link and mercury having a significant but complex relationship, emphasizing the need for targeted public health interventions.

Determination of per-and polyfluoroalkyl compounds in paper recycling grades using ultra-high-performance liquid chromatography–high-resolution mass spectrometry

11 Apr 2024 | Environ Sci Pollut Res Int

PFAS concentrations in paper products were found to be highest in post-consumer recycled paper, highlighting the need to reduce the use of paper additives and improve the collection and sorting of paper for recycled materials.

Estimating the dynamic early life exposure to PFOA and PFOS of the HELIX children: Emerging profiles via prenatal exposure, breastfeeding, and diet

9 Apr 2024 | Environ. Int.

Children's exposure to PFAS from birth to 12 years old was estimated using a model that revealed fluctuations in plasma concentrations influenced by factors such as fetal development, breastfeeding, and food intake, thereby highlighting the importance of investigating early-life exposure to enhance risk assessment.

PFAS Contamination in Europe: Generating Knowledge and Mapping Known and Likely Contamination with “Expert-Reviewed” Journalism

9 Apr 2024 | Environ Sci Technol

The "Forever Pollution Project" (FPP), a collaborative effort between journalists and scientific advisers, used investigative techniques to reveal widespread PFAS contamination across Europe, emphasizing the importance of data transparency and collaboration among researchers, policymakers, and journalists in addressing environmental issues.

Underestimated burden of per-and polyfluoroalkyl substances in global surface waters and groundwaters

8 Apr 2024 | Nature

This study compiled data from over 45,000 surface and groundwater samples worldwide to assess the global prevalence of PFAS contamination, revealing that many samples exceed safe drinking water guidelines.

Constraining global transport of perfluoroalkyl acids on sea spray aerosol using field measurements

5 Apr 2024 | Science Advances

PFAAs were found to be present in sea spray aerosols in global oceans at levels significantly higher than in seawater, indicating that sea spray aerosols emissions may be a major source of PFAAs in the atmosphere, comparable to or greater than other known sources such as manufacturing emissions and precursor degradation.