Application of soil amendments for reducing PFAS leachability and bioavailability

1 Jun 2022 | Environ. Pollut.

Through the use of commercially-available soil additives, the mobility and potential exposure to soil-borne PFAS was decreased by 98%.

Extraction of Chemical Structures from Literature and Patent Documents using Open Access Chemistry Toolkits: A Case Study with PFAS

1 Jun 2022 | Comput. Theor. Chem.

This work extracted ~1.7 M PFAS from patents and ~27 K from repositories to better understand how chemical structures are being normalized and communicated.

Are resource recovery insects safe for feed and food? A screening approach for bioaccumulative trace organic contaminants

1 Jun 2022 | Sci. Total Environ.

Four PFAS (PFBA, PFOA, PFBS, and PFOS) did not bioaccumulate in larvae, and non-target analysis revealed emerging PFAS present in larvae and almond hulls.

A High-Throughput Toxicity Screen of 42 Per- and Polyfluoroalkyl Substances (PFAS) and Functional Assessment of Migration and Gene Expression in Human Placental Trophoblast Cells

1 Jun 2022 | Front. Toxicol.

The placenta is potentially a direct target of PFAS exposure and indicate that trophoblast cell gene expression and function are disrupted at PFAS levels well below the predetermined cell mortality level.

Select Per- and Polyfluoroalkyl Substances (PFAS) Induce Resistance to Carboplatin in Ovarian Cancer Cell Lines

1 Jun 2022 | Int. J. Mol. Sci.

PFAS was associated with increased survival of ovarian cancer cells following specific cancer treatments.

Assessment of Bioactive Surfactant Levels in Selected Cereal Products

30 May 2022 | Applied Sciences

The most frequently detected compound was PFOA, which was quantified in 65.2% of samples, while PFBA was present in the majority of cereal based products.

Communicating Confidence of Per- and Polyfluoroalkyl Substance Identification via High-Resolution Mass Spectrometry

30 May 2022 | Environ. Sci. Technol. Lett.

A confidence scale system was developed for the identification of PFAS through mass spectrometry to aid scientific research, especially considering the lack of analytical reference standards for PFAS.

Extraction and Matrix Cleanup Method for Analyzing Novel Per- and Polyfluoroalkyl Ether Acids and Other Per- and Polyfluoroalkyl Substances in Fruits and Vegetables

24 May 2022 | J. Agric. Food Chem.

An extraction and cleanup method was developed to quantify 45 PFAS, including 13 PFEAs, 3 perfluoroalkane sulfonamides, and 6 fluorotelomer carboxylic acids in 10 types of fruits and vegetables.

Dermal uptake: An important pathway of human exposure to perfluoroalkyl substances?

24 May 2022 | Environ Pollut

The available literature on human dermal absorption of PFAS is critically reviewed and compared to other halogenated contaminants like brominated flame retardants, and the authors highlight the need for dermal permeation and uptake studies for a wide range of PFAS and their precursors.

PFAS use in electronic products and exposure risks during handling and processing of e-waste: A review

24 May 2022 | J Environ Manage

The wide use of PFAS in electronics presents a likely exposure source to workers at electronic-waste disposal sites given that PFAS have been detected in environmental and human samples near waste processing sites.

Influence of Perfluoroalkyl Substances on Occurrence of Coronavirus Disease 2019

24 May 2022 | Int J Environ Res Public Health

PFAS exposures occurring early in life may cause deleterious health effects later in life, including decreased antibody response and reduced disease resistance. Highest levels of both PFAS exposure and COVID-19 were found in the oldest populations.

Systematic Evidence Map for Over One Hundred and Fifty Per- and Polyfluoroalkyl Substances (PFAS)

24 May 2022 | Environ Health Perspect

More than 40,000 studies were identified to compile epidemiological evidence for 150 PFAS, and it was found that many PFAS lack sufficient data to determine health impacts.

Emerging and Legacy Per- and Polyfluoroalkyl Substances in an Elderly Population in Jinan, China: The Exposure Level, Short-Term Variation, and Intake Assessment

24 May 2022 | Environ Sci Technol

Dietary ingestion, especially fish, was likely an important exposure pathway for PFAS among elderly adults in one city.

Invited Perspective: The Promise of Fit-for-Purpose Systematic Evidence Maps for Supporting Regulatory Health Assessment

17 May 2022 | EHP

A primary goal of systematic evidence maps (SEMs) in environmental health is to gather large amounts of data to support deeper scientific analyses and decision-making that protects public health and the environment. SEMs can be extremely useful for assessing large chemical classes, such as PFAS. However, a comparison of two different SEM approaches highlights that many available PFAS studies might not be considered in the U.S. EPA health assessments.