First observations of a potential association between accumulation of per- and polyfluoroalkyl substances in the central nervous system and markers of Alzheimer's disease

31 Aug 2023 | J Gerontol A Biol Sci Med Sci

PFAS accumulation in the central nervous system was potentially linked to clinical and biological markers of Alzheimer’s disease.

Novel Per- and Polyfluoroalkyl Substances Discovered in Cattle Exposed to AFFF-Impacted Groundwater

30 Aug 2023 | Environ Sci Technol

The results suggest that targeting only the major PFAS analytes in bovine serum of AFFF-exposed mammals likely underestimates the toxicological risks associated with their exposure.

Association between a Mixture of Per- and Polyfluoroalkyl Substances (PFAS) and Inflammatory Biomarkers in the Atlanta African American Maternal-Child Cohort

30 Aug 2023 | Environ Sci Technol

Prenatal PFAS exposure is associated with an increase in multiple inflammatory biomarkers that may contribute to adverse pregnancy outcomes such as preeclampsia, premature labor, and fetal growth restriction.

Prenatal exposures to mixtures of endocrine disrupting chemicals and sex-specific associations with children's BMI and overweight at 5.5 years of age in the SELMA study

30 Aug 2023 | Environ Int

Prenatal exposure to a mixture of endocrine-disrupting chemicals was associated with lower BMI in only young girls, with chemicals of concern including phthalates, bisphenols, plasticizers, PAHs, and PFNA.

Prenatal and Childhood Per- and Polyfluoroalkyl Substance (PFAS) Exposures and Blood Pressure Trajectories From Birth to Late Adolescence in a Prospective US Prebirth Cohort

29 Aug 2023 | J Am Heart Assoc

Prenatal and childhood PFAS exposures were associated with blood pressure at specific times, but associations were not consistent across all time points or PFAS types.

Exposure to Per-and Polyfluoroalkyl Substances in Women With Twin Pregnancies: Patterns and Variability, Transplacental Transfer, and Predictors

28 Aug 2023 | J. Hazard. Mater.

PFOS, PFOA, and 6:2 Cl-PFESA were identified as the most dominant PFAS in both maternal and twin cord serum.

Toward Advancing Precision Environmental Health: Developing a Customized Exposure Burden Score to PFAS Mixtures to Enable Equitable Comparisons Across Population Subgroups, Using Mixture Item Response Theory

24 Aug 2023 | Environ Sci Technol

After analyzing national PFAS biomonitoring data with an algorithm that allows for better comparisons, researchers found that both Asian Americans and people with higher household incomes had higher PFAS burdens.

Assessment of poly- and perfluoroalkyl substances (PFAS) in commercially available drinking straws using targeted and suspect screening approaches

24 Aug 2023 | Food Addit Contam Part A Chem Anal Control Expo Risk Assess

PFAS were detected in all types of straws in the Belgian market except for stainless steel, with higher frequencies in glass and plant-based materials like paper and bamboo.

How Should We Interpret the New Water Quality Regulations for Per-and Polyfluoroalkyl Substances?

23 Aug 2023 | ACS ES&T Water

Proposed PFAS regulations should be coherent to minimize exposure and risks and remediation approaches should be balanced to reduce overall exposure across the various sources of exposure.

Chronic Exposure to a PFAS Mixture Resembling AFFF-Impacted Surface Water Decreases Body Size in Northern Leopard Frogs

23 Aug 2023 | Environ Sci Technol

Exposure to a PFAS mixture resembling those in AFFF-contaminated waters inhibits growth in amphibians undergoing metamorphosis in outdoor aquatic environments.

Temporal Decline in Serum PFAS Concentrations among Metropolitan Firefighters: Longitudinal Study on Post-Exposure Changes following PFAS Foam Cessation

22 Aug 2023 | Environ. Int.

After switching from AFFF to alternative firefighting foams, younger firefighters and those with minimal prior occupational PFAS exposure experienced substantially greater annual reductions in PFAS blood levels.

PFAS and Phthalate/DINCH Exposure in Association with Age at Menarche in Teenagers of the HBM4EU Aligned Studies

18 Aug 2023 | Toxics

Di(2-ethylhexyl) phthalate was linked to early onset of menstruation, whereas a limited to no such association was found with the three studied PFAS.

Determination of several PFAS groups in food packaging material from fast-food restaurants in France

14 Aug 2023 | Chemosphere

PFHxA, 6:2 FTS, and 6:2/6:2 diPAP were found in all fast-food packaging samples in France, along with many other PFAS found in certain samples.

Evaluation of sealants to mitigate the release of per-and polyfluoroalkyl substances (PFAS) from AFFF-impacted concrete: characterization and forecasting

14 Aug 2023 | Water Research X

Simulated rainfall scenarios indicate that sealing concrete surfaces previously contaminated with AFFF reduces the leaching of PFAS, while unsealed concrete surfaces could continue to release PFOS for a period of 15 years or more.

Prenatal and childhood exposure to per-/polyfluoroalkyl substances (PFASs) and its associations with childhood overweight and/or obesity: a systematic review with meta-analyses

14 Aug 2023 | Environ Health

The review revealed positive correlations between prenatal PFNA and BMI, between PFOA and BMI in children older than 3 years, as well as between prenatal PFNA and waist circumference. Negative associations were found between prenatal PFOS and BMI in children younger than 3 years and PFHxS and the risk of being overweight.