Unregulated Active and Closed Textile Mills Represent a Significant Vector of PFAS Contamination into Coastal Rivers
15 Dec 2023 | ACS ES&T Water
Sampling of rivers downstream from textile miles revealed higher concentrations of PFOS and PFCAs, demonstrating that both closed and active mills are important ongoing sources of PFAS to freshwater and marine regions.
Exposure to select PFAS and PFAS mixtures alters response to platinum-based chemotherapy in endometrial cancer cell lines
14 Dec 2023 | Environ Health
Exposure to PFAS may induce chemotherapy resistance or enhance therapeutic efficacy in some cancer cells by affecting the cells' energy synthesis capabilities in both cases.
Associations of a Prenatal Serum Per- and Polyfluoroalkyl Substance Mixture with the Cord Serum Metabolome in the HOME Study
13 Dec 2023 | Environ Sci Technol
Prenatal exposure to a mixture of PFAS in mothers is linked to alterations in infant metabolic pathways, which can result in birthweight or vaccine response abnormalities.
In vitro screening of per-and polyfluorinated substances (PFAS) for interference with seven thyroid hormone system targets across nine assays
10 Dec 2023 | Toxicology in Vitro
85 of 136 tested PFAS affected key molecular events in the thyroid and endocrine hormone system, potentially resulting in associated health and ecological effects.
[Perspective] Global Perspective on the Impact of Plastic Waste as a Source of Microplastics and Per-and Polyfluoroalkyl Substances in the Environment
8 Dec 2023 | ACS ES&T Water
Microplastics (MPs) and PFAS in the environment pose a serious threat to ecosystems and MPs act as carriers for PFAS, creating a secondary source of pollution–highlighting the need to better understand this interaction.
Associations of Prenatal Per- and Polyfluoroalkyl Substance (PFAS) Exposures with Offspring Adiposity and Body Composition at 16-20 Years of Age: Project Viva
6 Dec 2023 | Environ Health Perspect
Prenatal exposure to PFAS impacted the body weight and composition of teenagers, finding that higher concentrations of these substances were associated with an increased risk of obesity and altered BMI trajectories during late adolescence.
Dose Response, Dosimetric, and Metabolic Evaluations of Replacement PFAS Perfluoro-(2, 5, 8-trimethyl-3, 6, 9-trioxadodecanoic) Acid (HFPO-TeA)
4 Dec 2023 | toxics
HFPO-TeA, a GenX replacement, was found to cause increased mortality rates in higher doses, body weight changes at lower doses, thyroid hormone disruptions, and evidence of a complex and toxic exposure-response in rats.
Per- and polyfluoroalkyl substances (PFAS) in little penguins and associations with urbanisation and health parameters
4 Dec 2023 | Sci Total Environ
Tasmania penguins were found to be exposed to PFAS, with higher concentrations near urbanized breeding sites, resulting in potential health risks such as sex-specific associations with blood cell development and function.
Prenatal exposure to per- and polyfluoroalkyl substances and early childhood adiposity and cardiometabolic health in the Healthy Start study
2 Dec 2023 | IJO
Exposure to PFAS during pregnancy was found to be associated with increased body mass in early childhood, particularly in terms of precisely measured fat mass, emphasizing potential health implications for children exposed to PFAS during gestation.
Prenatal exposure to Per-and polyfluoroalkyl substances and adiposity measures of children at 4 and 6 years: A prospective birth cohort in China
1 Dec 2023 | Ecotoxicol Environ Saf
Exposure to PFAS during pregnancy was linked to increased adiposity in Chinese children at ages 4 and 6, with a stronger impact on measures like arm circumference and waist circumference, particularly among girls.
Carcinogenicity of perfluorooctanoic acid and perfluorooctanesulfonic acid
30 Nov 2023 | Lancet Onc.
A Working Group of 30 scientists from 11 countries met at the International Agency for Research on Cancer in Lyon, France, to finalise their evaluation of the carcinogenicity of two agents: PFOA and PFOS, including their corresponding isomers and salts.
Association between probiotic consumption and serum perfluoroalkyl and polyfluoroalkyl substances (PFAS): results from NHANES, 2003–2018
28 Nov 2023 | Environ. Sci. Eur.
The consumption of probiotics through yogurt or supplements is associated with lower levels of certain PFAS, suggesting potential health benefits.
Comparison of Serum PFAS Concentrations in Incumbent and Recruit Firefighters and Longitudinal Assessment in Recruits
28 Nov 2023 | J Occup Environ Med
Incumbent firefighters had lower n-PFOA and PFNA than recruits and most PFAS significantly decreased over time among male recruits, suggesting that firefighting activities may not increase PFAS exposure.
Characterizing the Movement of Per-and Polyfluoroalkyl Substances in an Avian Aquatic–Terrestrial Food Web
24 Nov 2023 | Environ. Sci. Technol.
Tree swallow nestlings were found to feed on both terrestrial and aquatic macroinvertebrates, leading to the bioaccumulation and biomagnification of PFAS, particularly PFOS, highlighting the complex and chemical-specific movement of PFAS through linked aquatic-terrestrial food webs.
Exposure to perfluoroalkyl substances and longitudinal changes in bone mineral density in adolescents and young adults: A multi-cohort study
23 Nov 2023 | Environ Res
Exposure to PFOS was found to be associated with lower bone mineral density in both Hispanic adolescents and mixed-ethnicity young adults, suggesting potential long-term impacts on bone health and increased risk of osteoporosis in adulthood.