Dietary exposure to per- and polyfluoroalkyl substances: Potential health impacts on human liver
21 Oct 2023 | Sci Total Environ
PFAS contamination in food poses an especially elevated risk of liver toxicity to infants and adolescents and primarily comes from biomagnification through the food chain and food contact materials.
Perfluoroalkyl substances in umbilical cord blood and blood pressure in offspring: a prospective cohort study
19 Oct 2023 | Environmental Health
Exposure to certain long-chain PFAS, particularly PFOS, PFDA, and PFUA, in umbilical cord blood was associated with lower blood pressure in offspring at the age of 4 years, with PFUA being the most significant contributor and PFDoA exhibiting a positive association with blood pressure.
Metabolic Perturbations Associated with an Exposure Mixture of Per-and Polyfluoroalkyl Substances in the Atlanta African American Maternal-Child Cohort
19 Oct 2023 | Environ Sci Technol
Prenatal exposure to a mixture of PFAS chemicals, including PFOA, PFNA, PFOS, and PFHxS, is associated with significant metabolic perturbations indicative of systemic inflammation and oxidative stress in pregnant African-American women, highlighting the importance of considering the joint effects of these chemicals on human health.
Prenatal Exposure to Multiple Endocrine-Disrupting Chemicals and Childhood BMI Trajectories in the INMA Cohort Study
18 Oct 2023 | Environ Health Perspect
Exposure to HCB, DDE, PCBs, and PFNA was linked to an increased risk of lower birth size followed by accelerated BMI gain in single-exposure models.
Novel Insights into the Adverse Health Effects of per- and Polyfluoroalkyl Substances on the Kidney via Human Urine Metabolomics
18 Oct 2023 | Environ Sci Technol
Individuals with high occupational exposure to PFAS were found to have positive correlations with urinary PFAS levels to key small kidney molecules and to serum PFAS levels, suggesting that urine can be an indicator of the adverse effects of high PFAS exposure on kidney health and that urine PFAS levels can be a good indicator for serum levels.
Association of per- and polyfluoroalkyl substance exposure with metabolic syndrome and its components in adults and adolescents
16 Oct 2023 | Environ Sci Pollut Res Int
A population-based study found that PFAS were negatively associated with the prevalence of metabolic syndrome in both adults and adolescents, although there were conflicting findings across different components of this syndrome, indicating a complex relationship between PFAS exposure and metabolic health.
Environmental exposure to legacy and emerging per- and polyfluoroalkyl substances and endometriosis in women of childbearing age
14 Oct 2023 | Sci. Total Environ.
PFOA and certain PFOS isomers were positively associated with an increased risk of endometriosis.
Nontarget Screening Strategies for PFAS Prioritization and Identification by High Resolution Mass Spectrometry: A Review
14 Oct 2023 | Trends Environ. Anal. Chem.
Advanced analytical techniques, like non-target screening using high-resolution mass spectrometry, have been developed to identify different PFAS and address challenges due to the vast number and diversity of these compounds and the lack of standards. However, difficulties remain in identifying unknown PFAS in complex environmental samples.
Elevated Levels of Ultrashort- and Short-Chain Perfluoroalkyl Acids in US Homes and People
11 Oct 2023 | Environ Sci Technol
This study observed strong connections between the amounts of TFA, PFBA, and PFHpA in dust or water and their presence in the bloodstream, indicating that inhaling dust or drinking contaminated water are significant ways people are exposed to these short and ultra-short PFAS.
Kinetics and Mechanism of Ultrasonic Defluorination of Fluorotelomer Sulfonates
9 Oct 2023 | J. Phys. Chem. A
Ultrasound waves were found to effectively break down FTSAs of various sizes with the potential to degrade other PFAS.
Serum per- and polyfluoroalkyl substance concentrations and longitudinal change in post-infection and post-vaccination SARS-CoV-2 antibodies
8 Oct 2023 | Environ Res
Higher levels of some PFAS in the bloodstream were associated with a lower initial immune response following infection but did not significantly affect the response to vaccination.
Estimation of the Half-Lives of Recently Detected Per- and Polyfluorinated Alkyl Ethers in an Exposed Community
6 Oct 2023 | Environ Sci Technol
The biological half-lives of fluoroethers were found to be shorter compared to PFOA and PFOS, but longer than PFHxA and PFHpA according to a model combining estimates from exposed populations and literature values.
Per-and polyfluoroalkyl substances (PFAS) in grocery store foods: method optimization, occurrence, and exposure assessment
5 Oct 2023 | Environ Sci Process Impact
Enhanced PFAS detection methods for various food types revealed that 16 out of 22 grocery store products contained PFAS with some foods exceeding recommended daily intake limits set by the EPA.
Combustion of high-calorific industrial waste in conventional brick kilns: An emerging source of PFAS emissions to agricultural soils
5 Oct 2023 | Sci Total Environ
The combustion of industrial waste in brick kilns was found to be a novel source of ultrashort-chain, short-chain, and legacy PFAS in Pakistan, exposing nearby communities to harmful levels of PFAS.
The sources and bioaccumulation of per-and polyfluoroalkyl substances in animal-derived foods and the potential risk of dietary intake
2 Oct 2023 | Sci. Total Environ.
This review highlights that PFAS can accumulate in animal-derived foods, particularly in seafood and meat, posing potential health risks, especially for women and children, and emphasizes the importance of understanding PFAS contamination in food safety management.