Early life exposure to low-dose perfluorooctane sulfonate disturbs gut barrier homeostasis and increases the risk of intestinal inflammation in offspring

24 Apr 2023 | Environ Pollut

Low-dose PFOS exposure disrupted the developing digestive functions in a human model species.

Association of perfluoroalkyl and polyfluoroalkyl substances with sex hormones in children and adolescents 6-19 Years of age

23 Apr 2023 | Environ Pollut

Serum concentrations of individual PFAS and mixtures were associated with changes in developmental hormone levels.

Mechanistic Middle-Out Physiologically Based Toxicokinetic Modeling of Transporter-Dependent Disposition of Perfluorooctanoic Acid in Humans

18 Apr 2023 | ES&T

A new model was developed to explain the persistence of PFOA in humans after both high-dose, acute and low-dose, chronic exposures.

Global ocean contamination of per- and polyfluoroalkyl substances: A review of seabird exposure

18 Apr 2023 | Chemosphere

Seabirds had higher levels of PFOS exposure – often exceeding toxicity reference values in places like the Baltic Sea and the San Francisco Bay – in the late 1990s and early 2000s, consistent with the phase-out of PFOS-based chemicals.

70 analyte PFAS test method highlights need for expanded testing of PFAS in drinking water

17 Apr 2023 | Sci. Total Environ.

Unregulated Contaminant Monitoring Rule will likely underreport PFAS in drinking water due to existing methods’ limited coverage and higher minimum reporting limits. The most common PFAS present was PFPrA, a poorly studied and monitored short-chain PFAS.

Pharmaceuticals Account for a Significant Proportion of the Extractable Organic Fluorine in Municipal Wastewater Treatment Plant Sludge

17 Apr 2023 | Environ. Sci. Technol. Lett.

Pharmaceutical substances and pesticides can contribute to sizable portions of the organofluorine content detected in wastewater treatment plant sludge.

Ecological characteristics impact PFAS concentrations in a US North Atlantic food web

17 Apr 2023 | Sci Total Environ

PFAS concentrations were related to species, body size, habitat, feeding guild, and location, with PFDA, PFOS, and FOSA levels being the highest in game species that live within the water column.

Weight loss relapse associated with exposure to perfluoroalkylate substances

17 Apr 2023 | Obesity

PFOA and PFHxS plasma concentrations were associated with increased weight gain, meaning obesogenic PFAS may cause weight gain and thus contribute to the obesity pandemic.

[Perspective] Avoiding the Next Silent Spring: Our Chemical Past, Present, and Future

13 Apr 2023 | ES&T

Learning from our past and present to improve a precautionary approach to persistent substances will ultimately allow humankind to avoid recurring silent springs.

Concentrations and isomer profiles of perfluoroalkyl carboxylates in house rats (Rattus norvegicus) and human blood: Implication for human exposure sources

11 Apr 2023 | Sci Total Environ

Fluorotelomer alcohol exposure and subsequent biotransformation is an important source of PFCAs in humans and rats that live nearby.

The exposure of Czech firefighters to perfluoroalkyl substances and polycyclic aromatic hydrocarbons: CELSPAC - FIREexpo case-control human biomonitoring study

11 Apr 2023 | Sci Total Environ

Total PFAS blood levels in firefighters were higher than the control group and were mostly associated with the length of a firefighting career, age, blood donation, and population size.

Perfluorinated Compounds (PFCs) in River Waters of Central Italy: Monthly Variation and Ecological Risk Assessment (ERA)

6 Apr 2023 | Arch Environ Contam Toxicol

PFOS concentrations were classified as medium to high risk for the aquatic environment in all river samples, which also frequently contained PFBA, PFPeA, PFHxA, and PFOA, especially in summer months.

Practical Semiquantification Strategy for Estimating Suspect Per- and Polyfluoroalkyl Substance (PFAS) Concentrations

5 Apr 2023 | J Am Soc Mass Spectrom

Development of a model PFAS calibration curve to determine the concentration of unknown or suspect PFAS.

Evaluating the Performance of Per- and Polyfluoroalkyl Substance Finishes on Upholstery Fabrics

3 Apr 2023 | AJOR

Superior stain performance for furniture textiles can be achieved through intentional material selection rather than PFAS treatments, which were shown to work only in limited situations.

Spatial and temporal variability of per- and polyfluoroalkyl substances (PFAS) in environmental media of a small pond: Toward an improved understanding of PFAS bioaccumulation in fish

1 Apr 2023 | Sci Total Environ

An analysis of surface water, sediment, and fish concentrations characterized the movement of PFAS in an entire pond.