Science

Co-exposure to perfluoroalkyl acids and heavy metals mixtures associated with impaired kidney function in adults: A community-based population study in China

6 Jun 2022 | Sci Total Environ

Co-exposure to PFAS and heavy metals was associated with reduced kidney function, especially due to As, Sr, and PFHpS.

Early-pregnancy plasma per- and polyfluoroalkyl substance (PFAS) concentrations and hypertensive disorders of pregnancy in the Project Viva cohort

6 Jun 2022 | Environ Int

Exposure to certain PFAS may increase the odds of gestational hypertension during pregnancy, with potential implications for maternal and child health outcomes.

Dietary Perfluorohexanoic Acid (PFHxA) Exposures in Juvenile Zebrafish Produce Subtle Behavioral Effects across Generations

4 Jun 2022 | Toxics

PFHxA juvenile dietary exposure induced abnormal adult behavior and anxiety in a multigenerational human model species.

Application of soil amendments for reducing PFAS leachability and bioavailability

1 Jun 2022 | Environ. Pollut.

Through the use of commercially-available soil additives, the mobility and potential exposure to soil-borne PFAS was decreased by 98%.

Extraction of Chemical Structures from Literature and Patent Documents using Open Access Chemistry Toolkits: A Case Study with PFAS

1 Jun 2022 | Comput. Theor. Chem.

This work extracted ~1.7 M PFAS from patents and ~27 K from repositories to better understand how chemical structures are being normalized and communicated.

Are resource recovery insects safe for feed and food? A screening approach for bioaccumulative trace organic contaminants

1 Jun 2022 | Sci. Total Environ.

Four PFAS (PFBA, PFOA, PFBS, and PFOS) did not bioaccumulate in larvae, and non-target analysis revealed emerging PFAS present in larvae and almond hulls.

A High-Throughput Toxicity Screen of 42 Per- and Polyfluoroalkyl Substances (PFAS) and Functional Assessment of Migration and Gene Expression in Human Placental Trophoblast Cells

1 Jun 2022 | Front. Toxicol.

The placenta is potentially a direct target of PFAS exposure and indicate that trophoblast cell gene expression and function are disrupted at PFAS levels well below the predetermined cell mortality level.

Select Per- and Polyfluoroalkyl Substances (PFAS) Induce Resistance to Carboplatin in Ovarian Cancer Cell Lines

1 Jun 2022 | Int. J. Mol. Sci.

PFAS was associated with increased survival of ovarian cancer cells following specific cancer treatments.

Assessment of Bioactive Surfactant Levels in Selected Cereal Products

30 May 2022 | Applied Sciences

The most frequently detected compound was PFOA, which was quantified in 65.2% of samples, while PFBA was present in the majority of cereal based products.

Communicating Confidence of Per- and Polyfluoroalkyl Substance Identification via High-Resolution Mass Spectrometry

30 May 2022 | Environ. Sci. Technol. Lett.

A confidence scale system was developed for the identification of PFAS through mass spectrometry to aid scientific research, especially considering the lack of analytical reference standards for PFAS.

Extraction and Matrix Cleanup Method for Analyzing Novel Per- and Polyfluoroalkyl Ether Acids and Other Per- and Polyfluoroalkyl Substances in Fruits and Vegetables

24 May 2022 | J. Agric. Food Chem.

An extraction and cleanup method was developed to quantify 45 PFAS, including 13 PFEAs, 3 perfluoroalkane sulfonamides, and 6 fluorotelomer carboxylic acids in 10 types of fruits and vegetables.

Dermal uptake: An important pathway of human exposure to perfluoroalkyl substances?

24 May 2022 | Environ Pollut

The available literature on human dermal absorption of PFAS is critically reviewed and compared to other halogenated contaminants like brominated flame retardants, and the authors highlight the need for dermal permeation and uptake studies for a wide range of PFAS and their precursors.

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