Toxicology assessment for six per- and polyfluoroalkyl (PFAS)-free aqueous film forming foam (AFFF) products

23 Feb 2023 | Integr Environ Assess Manag

PFAS-free AFFF products appear to have a lower likelihood of environmental persistence and bioaccumulation and have lower oral human health toxicity than PFAS-containing AFFF.

Metabolic Signatures of Youth Exposure to Mixtures of Per- and Polyfluoroalkyl Substances: A Multi-Cohort Study

22 Feb 2023 | EHP

Exposure to PFAS was associated with alterations in amino acid metabolism and lipid metabolism in young adults.

Per-and polyfluoroalkyl substances and volatile methyl siloxanes in global air: Spatial and temporal trends

22 Feb 2023 | Env. Poll.

Long-chain PFAS were detected globally in the environment, with PFOS levels still increasing at several sites despite its listing as a persistent organic pollutant to the Stockholm Convention since 2009.

Early-life exposure to per- and polyfluoroalkyl substances and infant gut microbial composition

22 Feb 2023 | Environ Epidemiol

PFAS may increase infant gut microbiome diversity and alter the relative abundance of biologically relevant bacteria.

Exposure to serum perfluoroalkyl substances and biomarkers of liver function: The Korean national environmental health survey 2015-2017

21 Feb 2023 | Chemosphere

Higher serum PFOA, PFOS, PFHxS, PFDA, and PFNA concentrations were related to higher serum concentrations of liver enzymes, although some differences were dependent on sex and obesity status.

Pregnancy-related hemodynamic biomarkers in relation to trimester-specific maternal per - and polyfluoroalkyl substances exposures and adverse birth outcomes.

20 Feb 2023 | Environ Pollut

Prenatal PFAS exposures during each trimester resulted in different adverse health effects.

Exposure to high levels of PFAS through drinking water is associated with increased risk of type 2 diabetes-findings from a register-based study in Ronneby, Sweden

20 Feb 2023 | Environ Res

A higher risk of type 2 diabetes among individuals aged 18–45 years was found, suggesting increased susceptibility to PFAS-related health effects at younger ages.

Prenatal Exposure to Legacy and Alternative Per- and Polyfluoroalkyl Substances and Neuropsychological Development Trajectories over the First 3 Years of Life

17 Feb 2023 | Environ Sci Technol

Mothers’ elevated serum levels of PFHxS, PFOS, and other PFAS mixtures were associated with decreased communication and problem-solving abilities throughout their children’s first 36 months of life.

Target and Nontarget Screening of PFAS in Drinking Water for a Large-Scale Survey of Urban and Rural Communities in Québec, Canada

16 Feb 2023 | Water Res

99.3% of 463 tap water samples from Québec, Canada, had detectable levels of PFAS, including compounds not currently included in US EPA methods for drinking water testing.

Associations between serum per-and polyfluoroalkyl substances and asthma morbidity in the National Health and Nutrition Examination Survey (2003-2018)

13 Feb 2023 | JACI

Elevated levels of serum PFOA and PFDA may be associated with greater odds of asthma attacks in the 12–18-year-old group, but further study is needed.

Comprehensive target analysis and TOP assay of per-and polyfluoroalkyl substances (PFAS) in wild boar livers indicate contamination hot-spots in the environment

13 Feb 2023 | Sci Total Environ

Wild boar livers were found to be suitable bioindicators for PFAS in the environment.

Occurrence of Quantifiable and Semi-Quantifiable Poly- and Perfluoroalkyl Substances in United States Wastewater Treatment Plant

10 Feb 2023 | Water Research

Quantifiable & semi-quantifiable PFAS were found in the influent, effluent, and biosolids at every facility sampled, with most PFAS discharging via aqueous effluent.

Systematic review and meta-analysis of epidemiologic data on vaccine response in relation to exposure to five principal perfluoroalkyl substances

7 Feb 2023 | Environ Int

Serum PFAS concentrations may reduce antibody response after vaccination, especially for diphtheria, rubella, and tetanus.

Associations between serum per- and polyfluoroalkyl substances and asthma morbidity in the National Health and Nutrition Examination Survey (2003-18)

6 Feb 2023 | J Allergy Clin Immunol Glob

PFOA exposure was associated with asthma attacks in 12-18-year olds.