Longitudinal measurements of per-and poly-fluoroalkyl substances (PFAS) in archived human serum samples between 1975 and 1995 in Australia

1 Nov 2022 | J. Hazard. Mater.

Repeat serum samples collected from 17 participants in 1975, 1981 and 1995 were analyzed for 35 PFAS, revealing increasing detection frequencies over time and a 7-fold increase in median summed PFAS concentrations from 1975 to 1995.

What do we know about the production and release of persistent organic pollutants in the global environment?

26 Oct 2022 | Environ. Sci. Adv.

The U.S. has the highest cumulative environmental releases of PFOS, whereas Europe has the highest cumulative environmental releases of PFOA.

Maternal Offloading of Per-and Polyfluoroalkyl Substances to Eggs by Lake Michigan Salmonids

25 Oct 2022 | ES&T

Salmon can bioaccumulate and offload PFAS to embryos, which has implications for embryo health, egg predation by wildlife, and ultimately human exposure.

PFAS and Precursor Bioaccumulation in Freshwater Recreational Fish: Implications for Fish Advisories

24 Oct 2022 | Environ Sci Technol

PFAS precursors were found to have higher bioaccumulation potentials than PFAS commonly considered in regulatory efforts, suggesting that more comprehensive fish advisories are needed to prevent human exposures.

[Commentary] Improving governance of “forever chemicals” in the US and beyond

21 Oct 2022 | One Earth

Dramatically reducing PFAS production, use, and exposure requires innovative governance interventions, proactive and conscientious business actions, and scientific advances that defy disciplinary boundaries, all guided by the voices, experiences, and needs of impacted communities.

Blood Concentrations of Per-and Polyfluoroalkyl Substances are Associated with Autoimmune-like Effects in American Alligators from Wilmington, North Carolina

20 Oct 2022 | Frontiers in Toxicology

PFAS was found to broadly alter immune activities resulting in autoimmune-like diseases in American alligators.

Prenatal exposure to perfluorooctane sulfonate alternatives and associations with neonatal thyroid stimulating hormone concentration: A birth cohort study

20 Oct 2022 | Chemosphere

Higher concentrations of prenatal PFBS was associated with lower developmental hormone concentrations in newborns.

[Perspective] EPA Takes Action Against Harmful "Forever Chemicals" in the US Water Supply

19 Oct 2022 | JAMA

This Medical News article discusses new EPA advisories for PFAS as well as new National Academies guidance on expanded testing for exposure.

Exposure to a mixture of per-and polyfluoroalkyl substances modulates pulmonary expression of ACE2 and circulating hormones and cytokines

18 Oct 2022 | Toxicol Appl Pharmacol

The effects of PFAS exposure in mice on gene expression and hormones were studied with respect to susceptibility to viral infections such as COVID-19.

Analysis of Per- and Poly(fluoroalkyl) Substances (PFASs) in Highly Consumed Seafood Products from U.S. Markets

17 Oct 2022 | J Agric Food Chem

Bottom-feeding organisms tend to have the highest PFAS concentrations, followed by lean fish, fatty fish, and aquaculture with PFUdA and PFDoA being the most frequently detected chemicals.

Plasma concentrations of perfluoroalkyl acids and their determinants in youth and adults from Nunavik, Canada

14 Oct 2022 | Chemosphere

Long-chain PFAAs levels were 4–7 fold higher in Nunavik Inuit adults compared to the Canadian population and were associated with hunting activity, omega-3 fatty acids, and drinking water from environmental sources.

Per- and polyfluoroalkyl substances and psychosocial stressors have a joint effect on adverse pregnancy outcomes in the Atlanta African American Maternal-Child cohort

14 Oct 2022 | Sci Total Environ

Psychosocial stress including depression, anxiety, stress, and gendered racial stress may amplify associations between an increase in PFAS and reduced birthweight.

Occurrences of legacy and emerging per-and polyfluoroalkyl substances in human milk in China: Results of the third National Human Milk Survey (2017–2020)

12 Oct 2022 | J. Hazard. Mater.

Potential hazard from PFAS exposure through breastmilk, especially from high PFOA exposure, was observed throughout China.

Presumptive Contamination: A New Approach to PFAS Contamination Based on Likely Sources

12 Oct 2022 | ES&T

A contamination model was used to create a map of presumptive PFAS contamination sites in the United States, identifying more than 57,000 sites including industrial facilities, wastewater treatment plants, current or former military sites, and airports.

Use and release of per-and polyfluoroalkyl substances (PFASs) in consumer food packaging in US and Canada

11 Oct 2022 | Chemosphere

Most food packaging does not contain intentionally added PFAS, indicating that PFAS are not necessary for food packaging, yet the thousands of tonnes of PFAS still used have the potential to contaminate the environment and waste streams.