Current Breast Milk PFAS Levels in the United States and Canada: After All This Time, Why Don't We Know More?
28 Feb 2022 | Environ Health Perspect
The authors emphasize the need to study PFAS in breast milk and found that all average estimated and measured breast milk PFOA and PFOS concentrations exceeded drinking water screening values for children, sometimes by more than two orders of magnitude.
Maternal Perfluorinated Compound Exposure and Risk of Early Pregnancy Loss: A Nested Case-control Study
28 Feb 2022 | Biomed Environ Sci
Higher maternal serum concentrations of PFDA and PFUdA were associated with an elevated risk of early pregnancy loss within 12 weeks of gestation.
Association between maternal per- and polyfluoroalkyl substance exposure and newborn telomere length: Effect modification by birth seasons
28 Feb 2022 | Environ Int
A higher maternal PFOA concentration was significantly associated with shorter newborn telomere length in spring-born infants but not in those born in other seasons.
Early Warnings by Liver Organoids on Short- and Long-Chain PFAS Toxicity
28 Feb 2022 | Toxics
Short-chain PFAS were found to reduce the structural integrity and disrupt normal cell functions in a synthetic tissue model.
Evaluation and validation of methodologies for the extraction of per- and polyfluoroalkyl substances (PFASs) in serum of birds and mammals
28 Feb 2022 | Anal Bioanal Chem
Protein precipitation and enhanced matrix removal were found to be fast and effective methodologies for the extraction of PFAS from low volumes of serum.
From cohorts to molecules: Adverse impacts of endocrine disrupting mixtures
21 Feb 2022 | Science
A mixture of endocrine-disrupting chemicals identified in pregnant women, including PFAS, phthalates, and BPA, were found to cause abnormalities in two model organisms and may also be associated with language delay in humans.
Enhancing Scientific Support for the Stockholm Convention’s Implementation: An Analysis of Policy Needs for Scientific Evidence
21 Feb 2022 | ES&T
Scientists discuss the success of the Stockholm Convention for addressing global threats of PFAS and provide guidance for further support of the Convention.
Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances (PFAS)
21 Feb 2022 | Environ Sci Technol
Non-targeted analysis of archived and new pine needle samples revealed over 70 PFAS, including both legacy PFAAs and their emerging replacements such as chlorinated derivatives, ultrashort chain PFAS, perfluoroalkyl ether acids, and more.
Spatial distribution and load of per- and polyfluoroalkyl substances (PFAS) in background soils in Sweden
21 Feb 2022 | Chemosphere
Sixteen out of 28 measured PFAS were detected in forest soils across Sweden with concentrations of PFOS explained by population density. The estimated total PFAS sink in soil throughout Sweden was on the order of several tons.
Risk of Cancer in a Community Exposed to Per- and Poly-Fluoroalkyl Substances
20 Feb 2022 | Environ Health Insights
Merrimack residents experienced a significantly higher risk of at least 4 types of cancer between 2005 and 2014 which may be linked to PFAS-contaminated drinking water.
Insights into the effects of salinity on the sorption and desorption of legacy and emerging per-and polyfluoroalkyl substances (PFASs) on marine sediments
16 Feb 2022 | Environ Pollut
The desorption rate of PFAS from marine sediment decreases with increased perfluorocarbon chain length of PFAS and increased sediment salinity.
Noise-Reduced Quantitative Fluorine NMR Spectroscopy Reveals the Presence of Additional Per- and Polyfluorinated Alkyl Substances in Environmental and Biological Samples When Compared with Routine Mass Spectrometry Methods
15 Feb 2022 | Anal Chem
Novel techniques were applied to increase the sensitivity of fluorine NMR such that more PFAS were found in aqueous samples compared to traditional LC-MS methods, suggesting NMR as a simple and accurate tool to measure total organic fluorine.
Concentrations of per- and polyfluoroalkyl substances (PFAS) in human placental tissues and associations with birth outcomes
15 Feb 2022 | Chemosphere
All tested placenta samples contained detectable PFAS, including PFOS, PFOA, PFNA, and PFDA in >96% samples, and placental PFOS was associated with lower birth weight for in male infants and higher birth weight in female infants.
Human exposure to F-53B in China and the evaluation of its potential toxicity: An overview
15 Feb 2022 | Environ Int
A review of a novel PFAS demonstrated hepatotoxicity, endocrine disruption, reproductive, and developmental toxicity, and suggested further research given the extreme biopersistence of F-53B.
Sulfonamide functional head on short-chain perfluorinated substance drives developmental toxicity
15 Feb 2022 | iScience
FBSA significantly disrupted normal gene expression in a human model species while other short-chain PFAS induced changes in larval behavior.