Analysis of per- and poly-fluoroalkyl substances (PFAS) in processed foods from FDA's Total Diet Study

31 Aug 2021 | Anal Bioanal Chem

PFAS features detected by LC-MS/MS correlated well in abundance with LC-IMS-MS data; however, LC-IMS-MS identified a number of additional PFAS, many known to be components of firefighting foams.

Early pregnancy loss: Do Per- and polyfluoroalkyl substances matter?

31 Aug 2021 | Environ Int

Overall, we suggest that most PFAS were not associated with early pregnancy loss at the current exposure levels.

Perfluorobutanoic acid (PFBA): No high-level accumulation in human lung and kidney tissue

30 Aug 2021 | Int J Hyg Environ Health

Contrary to previous findings, analysis of short-chain PFAS in human lungs and kidney indicates PFBA is not likely to accumulate in these tissues.

The occurrence of per- and polyfluoroalkyl substances (PFASs) in fluoropolymer raw materials and products made in China

25 Aug 2021 | J Environ Sci (China)

Generally, the levels of PFOA in raw materials were higher than in products, implying that PFOA in the emulsion/dispersion resin could be partly removed during the polymerization or post-processing steps.

Occurrence of perfluoroalkyl substances (PFASs) in marine plastic litter from coastal areas of Central Chile

25 Aug 2021 | Mar Pollut Bull

Long-chain PFAS, which can be metabolically degraded into PFOS, were found on six South American beaches in plastic debris.

The Dilemma of Perfluorooctanoate (PFOA) Human Half-life

25 Aug 2021 | Regul Toxicol Pharmacol

Based on information from both human observational studies and clinical data, we proposed a range for the half-life for PFOA of 0.5 to 1.5 years, which would likely raise many existing regulatory safe levels if all other parameters stayed the same.

External and internal human exposure to PFOA and HFPOs around a mega fluorochemical industrial park, China: Differences and implications

25 Aug 2021 | Environ Int

PFAS were detected in human hair, and their compositions were similar to those in human serum, suggesting that hair is a good non-invasive indicator for long-term exposure to legacy long-chain perfluoroalkyl carboxylic acids and HFPOs.

Perfluoroalkyl substances (PFAS) in drinking water and risk for polycystic ovarian syndrome, uterine leiomyoma, and endometriosis: A Swedish cohort study

25 Aug 2021 | Environ Int

Exposure to high levels of PFAS in drinking water was associated with an increased risk of enlarged and irritated ovaries.

Chlorinated polyfluoroalkyl ether sulfonic acids in fish, dust, drinking water and human serum: From external exposure to internal doses

25 Aug 2021 | Environ Int

The modeled serum concentrations of 6:2 Cl-PFESA were higher than its observed levels hinting at its gradually increasing exposure levels in the general population.

Removal of per- and poly-fluoroalkyl substances (PFASs) by wetlands: Prospects on plants, microbes and the interplay

25 Aug 2021 | Sci Total Environ

The choice of plants and bacterial species is however crucial for the bioremediation of PFAS, and the system efficiency relies on species-specific, sediment-specific, and pollutant-specific principles.

Exposure to endocrine disrupting chemicals (EDCs) and cardiometabolic indices during pregnancy: The HOME Study

25 Aug 2021 | Environ Int

HFPO-DA was found to potentially be a major problem of health risk that affects inflammation, gut barrier dysfunction, and gut microbiota disturbance in mammals.

Correlates of plasma concentrations of per- and poly-fluoroalkyl substances among reproductive-aged Black women

24 Aug 2021 | Environ Res

PFAS exposure was strongly associated with reproductive factors such as reduced concentrations with parity, recent birth, lactation, and heavy menstrual bleeding in black women.

Perfluorinated compounds disrupted osmoregulation in Oryzias melastigma during acclimation to hypoosmotic environment

18 Aug 2021 | Ecotoxicol Environ Saf

PFOS showed a greater impact on fish’s ability to extract oxygen from fresh and saltwater than the shorter chain homolog PFBS.

Perfluorooctane sulfonate (PFOS) disturbs fatty acid metabolism in Caenorhabditis elegans: Evidence from chemical analysis and molecular mechanism exploration

17 Aug 2021 | Chemosphere

PFOS was found to inhibit energy synthesis during fatty acid metabolism in a model species.

Perfluoroalkyl substances are increased in patients with late-onset ulcerative colitis and induce intestinal barrier defects in murine intestinal tissue.

17 Aug 2021 | Scand J Gastroenterol

PFAS was found to irritate the intestinal tract leading to inflammatory bowel disease later in life.