Exposure to perfluoroalkyl substances was associated with estrogen homeostasis in pregnant women

30 Nov 2021 | Sci Total Environ

Exposure to PFAS disturbed hormone levels in pregnant women and the effects varied with the time periods of exposure during pregnancy.

PFASs pollution in Galveston Bay surface waters and biota (shellfish and fish) following AFFFs use during the ITC fire at Deer Park (March 17th-20th 2019), Houston, TX

30 Nov 2021 | Sci Total Environ

High PFAS levels were measured in water following AFFF usage on a nearby petrochemical fire and a risk assessment suggested a fish consumption advisory to protect against human exposure.

Species- and Tissue-Specific Chronic Toxicity Values for Northern Bobwhite Quail (Colinus virginianus) Exposed to PFHxA and a Binary Mixture of PFOS and PFHxA

30 Nov 2021 | Environ Toxicol Chem

PFHxA was more toxic to reproducing birds than either PFOS or a PFOS:PFHxS mixture, suggesting that avian PFAS toxicity is not necessarily additive.

Distribution and ten-year temporal trends (2009-2018) of perfluoroalkyl substances in gull eggs from Spanish breeding colonies

30 Nov 2021 | Environ Pollut

Total PFAS concentrations in gull eggs decreased through the 10-year study period in all but one colony, highlighting the usefulness of gull eggs as bioindicators of PFAS pollution in water and fish.

Distribution, source identification and health risk assessment of PFASs in groundwater from Jiangxi Province, China

30 Nov 2021 | Chemosphere

Monitoring in China suggests that PFBA, PFPeA, 6:2 FTS and F–53B are broadly used replacements of PFOA and PFOS with estimated daily intakes of short-chain PFCAs higher than that of PFOA.

Per- and Poly-fluoroalkyl Substances (PFAS) and Female Reproductive Outcomes: PFAS Elimination, Endocrine-Mediated Effects, and Disease

30 Nov 2021 | Toxicology

A summary of the role of PFAS in female reproductive dysfunction and disease is presented with the major data gaps, highlighting the importance for further study of the action mechanisms of PFAS harm in women.

Tumor and serum levels of per- and polyfluoroalkyl (PFAS) in hepatobiliary and gastrointestinal malignancy

30 Nov 2021 | Am J Surg

Cancer patients had higher levels of PFOS than the national average and those with higher blood serum levels of PFOS were more likely to have higher levels of PFOS in tumors.

Uptake of perfluoroalkyl substances, pharmaceuticals, and parabens by oyster mushrooms (Pleurotus ostreatus) and exposure risk in human consumption

24 Nov 2021 | Chemosphere

Uptake of PFAS by oyster mushrooms was negatively correlated with perfluorocarbon chain length, and mushrooms grown in soil contaminated by PFAS may pose a risk if consumed.

Thermal processing reduces PFAS concentrations in blue food – A systematic review and meta-analysis

23 Nov 2021 | EcoEvoRxiv

Initial recommendations were developed to reduce PFAS in fish via cooking using common kitchen items and cooking techniques.

Surface-water/groundwater boundaries affect seasonal PFAS concentrations and PFAA precursor transformations

23 Nov 2021 | Environ Sci Process Impacts

Natural biogeochemical fluctuations associated with surface-water and groundwater boundaries may lead to PFAA precursor loss and seasonal variations in PFAA concentrations.

Impairment of human dopaminergic neurons at different developmental stages by perfluoro-octanoic acid (PFOA) and differential human brain areas accumulation of perfluoroalkyl chemicals

23 Nov 2021 | Environ Int

In a proof-of-concept study, PFOA exposure was found to disrupt the most sensitive stage of neuron development.

Perfluorooctane sulfonate (PFOS) induces several behavioural defects in Caenorhabditis elegans that can also be transferred to the next generations

23 Nov 2021 | Chemosphere

PFOS can exert severe neurobehavioral defects in locomotion, lifespan, and reproduction that can be transferred from parents to their offspring in a human model species.

Per- and Polyfluoroalkyl Substances (PFAS): Significance and Considerations within the Regulatory Framework of the USA

23 Nov 2021 | Int J Environ Res Public Health

Regulatory agencies must start being proactive instead of reactive with PFAS contamination.

Immunotoxicity mechanisms of perfluorinated compounds PFOA and PFOS

23 Nov 2021 | Chemosphere

Mechanisms of PFOA and PFOS immunotoxicity in humans and animals were summarized.