Fluoroalkylether compounds affect microbial community structures and abundance of nitrogen cycle-related genes in soil-microbe-plant systems
13 Dec 2021 | Ecotoxicol. Environ. Saf.
Different ether-PFAS affected soil microbial community structure and function, sometimes inhibiting the ability of bacteria to transform environmental nitrogen.
A Bad Start in Life? Maternal Transfer of Legacy and Emerging Poly- and Perfluoroalkyl Substances to Eggs in an Arctic Seabird
13 Dec 2021 | Environ Sci Technol
Researchers identified 7:3 fluorotelomer carboxylic acid in 84% of seabird egg yolks and provided the first documented finding of ADONA in wildlife.
Montmorillonite clay-based sorbents decrease the bioavailability of per- and polyfluoroalkyl substances (PFAS) from soil and their translocation to plants
13 Dec 2021 | Environ Res
The addition of amended clay to soils was found to reduce the uptake of PFAS into edible crops by up to 74%.
Maternal consumption of ultra-processed foods and newborn exposure to perfluoroalkyl substances (PFAS)
13 Dec 2021 | Cad Saude Publica
Infants were found to have higher levels of PFAS if their mothers ate processed foods at least three times a week.
Life-Time Environmental Chemical Exposure and Obesity: Review of Epidemiological Studies Using Human Biomonitoring Methods
13 Dec 2021 | Front Endocrinol (Lausanne)
A review of chemical exposure and obesity found that PFOA has consistent obesogenic effects in humans.
The use of in vitro methods in assessing human health risks associated with short-chain perfluoroalkyl and polyfluoroalkyl substances (PFAS)
13 Dec 2021 | J Appl Toxicol
This review summarizes the PFAS toxicity data obtained using human cells in vitro, discusses the advantages and limitations of cell-based models, and provides thoughts on potential solutions to the challenges of these methods.
PFOA induces alteration in DNA methylation regulators and SARS-CoV-2 targets and in mouse lung tissues
12 Dec 2021 | Toxicol Rep
PFOA was found to change gene expression in lungs, potentially increasing susceptibility to COVID-19.
Tumorigenic activity of alternative per- and polyfluoroalkyl substances (PFAS): Mechanistic in vitro studies
6 Dec 2021 | Sci Total Environ
PFHxS has been associated with breast cancer in epidemiological studies, and this study demonstrated how this shorter-chain PFAS can affect cell proteins and cell proliferation.
Exposure of male mice to perfluorooctanoic acid induces anxiety-like behaviors by increasing corticotropin-releasing factor in the basolateral amygdala complex
6 Dec 2021 | Chemosphere
PFOA exposure in mice led to a metabolic cascade of effects resulting in anxiety-like behaviors.
Perfluorooctane sulfonate (PFOS) exposure of bovine oocytes affects early embryonic development at human-relevant levels in an in vitro model
6 Dec 2021 | Toxicology
Human-relevant levels of PFOS alter early bovine embryo development in vitro.
In Vivo Transformation of a Novel Polyfluoroether Surfactant
6 Dec 2021 | Environ Toxicol Chem
Rats that received a novel PFAS surfactant orally rather than intravenously had higher breakdown products in their blood suggesting the importance of metabolism in the gut and liver.
Perfluorooctane sulfonate induces heart toxicity involving cardiac apoptosis and inflammation in rats
6 Dec 2021 | Exp Ther Med
Exposure to PFOS left rats with heart inflammation and other markers of cardiac toxicity.
Prenatal exposure to poly-/per-fluoroalkyl substances is associated with alteration of lipid profiles in cord-blood
30 Nov 2021 | Metabolomics
Prenatal PFAS exposure may explain associations between PFAS exposure and adverse health conditions later in life, such as type 2 diabetes.
Poly- and Perfluorinated Alkyl Substances in Air and Water from Dhaka, Bangladesh.
30 Nov 2021 | Environ Toxicol Chem
The prevalence of 6:2 FTOH and PFBA across sites likely reflects their usage in textile manufacturing and could indicate the industry's switch to shorter chain PFAS.
Impaired gross motor development in infants with higher PFAS concentrations
30 Nov 2021 | Environ Res
Maternal fish intake determined infant PFAS levels and was associated with poorer infant gross motor development.