A Roadmap to the Structure-Related Metabolism Pathways of Per- and Polyfluoroalkyl Substances in the Early Life Stages of Zebrafish

27 Jul 2021 | Environ Health Perspect

Five structural categories of PFAS were prone to metabolism with perfluoroalkyl carboxamides showing the highest hydrolysis rates, followed by carboxyesters and sulfonamides.

Lactic acid bacteria alleviate liver damage caused by perfluorooctanoic acid exposure via antioxidant capacity, biosorption capacity and gut microbiota regulation

27 Jul 2021 | Ecotoxicol Environ Saf

The antioxidant capabilities of lactic acid bacteria were found to alleviate PFOA toxicity.

Prenatal exposure to per- and polyfluoroalkyl substances (PFAS) and associations with attention-deficit/hyperactivity disorder and autism spectrum disorder in children

27 Jul 2021 | Environ Res

Prenatal exposure to PFOA was associated with an increased risk of autism spectrum disorder and ADHD in children.

Do perfluoroalkyl substances aggravate the occurrence of obesity-associated glucolipid metabolic disease?

27 Jul 2021 | Environ Res

PFASs should be taken into account to explain the high prevalence of obesity-related lipid diseases.

Associations of single and multiple per- and polyfluoroalkyl substance (PFAS) exposure with vitamin D biomarkers in African American women during pregnancy

27 Jul 2021 | Environ Res

PFAS may affect vitamin D biomarker concentrations in pregnant African American women, and some of the associations were modified by fetal sex.

Distribution characteristics of per- and polyfluoroalkyl substances (PFASs) in human urines of acrylic fiber plant and chemical plant

26 Jul 2021 | Environ Sci Pollut Res Int

Short-chain PFASs (such as: PFBA and PFBS) were becoming dominant for human exposure, especially occupational workers.

Thyroid Disruptors: Extrathyroidal Sites of Chemical Action and Neurodevelopmental Outcome-an Examination Using Triclosan and Perfluorohexane Sulfonate (PFHxS)

21 Jul 2021 | Toxicol Sci

Lifelong exposure to PFAS could affect both the thyroid hormone status and the immune defense of perch in the wild.

Spatial and Temporal Patterns of PFAS Occurrence at a Wastewater Beneficial Reuse Site in Central Pennsylvania

20 Jul 2021 | ASABE

PFAS present in the crop tissue suggests that PFAS may enter the food chain once those crops are fed to livestock.

Placental Transfer and Composition of Perfluoroalkyl Substances (PFASs): A Korean Birth Panel of Parent-Infant Triads

20 Jul 2021 | Toxics

Gestational age and birth weight were positively associated with a placental transfer rate of PFOA, PFHxS, and PFOS, while pre-pregnant BMI and weight were inversely associated with PFOS.

Perfluorononanoic acid impedes mouse oocyte maturation by inducing mitochondrial dysfunction and oxidative stress

20 Jul 2021 | Reprod Toxicol

PFNA was found to inhibit the development of immature eggs preventing successful reproduction.

Perfluoroalkyl substances (PFAS) adsorption in drinking water by granular activated carbon: Influence of activated carbon and PFAS characteristics

20 Jul 2021 | Sci Total Environ

Activated carbon filters were found to absorb different PFAS from contaminated water at different efficiencies.

Chronic low-level perfluorooctane sulfonate (PFOS) exposure promotes testicular steroidogenesis through enhanced histone acetylation

20 Jul 2021 | Environ Pollut

Low-level PFOS exposure was found to promote the development of steroid hormones.

Exposure to perfluorooctane sulfonate in vitro perturbs the quality of porcine oocytes via induction of apoptosis

20 Jul 2021 | Environ Pollut

PFOS exposure leads to decreased reproductive success by decreasing viable sperm count.

Perfluoroalkyl substances (PFASs) in leachate, fly ash, and bottom ash from waste incineration plants: Implications for the environmental release of PFAS

19 Jul 2021 | Sci Total Environ

PFBA and PFBS were associated with leachate contamination while PFOS was found to travel in fly ash readily.

Why is elevation of serum cholesterol associated with exposure to perfluoroalkyl substances (PFAS) in humans? A workshop report on potential mechanisms

19 Jul 2021 | Toxicology

In this report, we summarize the relevant background data, the discussion among the attendees, and their recommendations for further research.