Early-Life Exposure to Per- and Poly-Fluorinated Alkyl Substances and Growth, Adiposity, and Puberty in Children: A Systematic Review

27 Oct 2021 | Front Endocrinol (Lausanne)

Children that are exposed to PFAS were found to have altered hormone and endocrine systems at various stages of their development.

Issues in the hazard and risk assessment of perfluoroalkyl substance mixtures.

27 Oct 2021 | Toxicol Lett

This commentary summarizes some of the issues and pitfalls of grouping a large number of structurally diverse compounds - many with limited exposure and absent toxicity database.

Cancer incidence in a Swedish cohort with high exposure to perfluoroalkyl substances in drinking water

26 Oct 2021 | Environ Res

Analysis of a large cohort exposed to high levels of PFAS, dominated by PFHxS and PFOS, revealed a moderately increased risk of kidney cancer.

Application of a Framework for Grouping and Mixtures Toxicity Assessment of PFAS: A Closer Examination of Dose-Additivity Approaches

21 Oct 2021 | SOT

This article presents a new and systematic analysis of available PFAS toxicity study data using a tiered mixtures risk assessment framework consistent with the United States and international mixtures guidance.

Association between the total plasma isomers of per- and polyfluoroalkyl substances and erythrograms in young and middle-aged Taiwanese populations.

14 Oct 2021 | Ecotoxicol Environ Saf

PFOA and PFOS isomers may increase the weight and volume of red blood cells.

Concentration profiles of per- and polyfluoroalkyl substances in major sources to the environment

12 Oct 2021 | J. Environ. Manage.

Precursor biotransformation products are detected in landfill leachates and wastewater-related sources.

Associations between both legacy and alternative per- and polyfluoroalkyl substances and glucose-homeostasis: The Isomers of C8 health project in China

12 Oct 2021 | Environ Int

Legacy and alternative PFASs were positively associated with potential markers for diabetes.

Associations between Novel and Legacy Per- and Polyfluoroalkyl Substances in Human Serum and Thyroid Cancer: A Case and Healthy Population in Shandong Province, East China

12 Oct 2021 | Environ Sci Technol

PFAS such as PFNA was found to disrupt normal thyroid function and may be associated with thyroid cancer.

Dietary predictors of prenatal per- and poly-fluoroalkyl substances exposure

12 Oct 2021 | J Expo Sci Environ Epidemiol

The consumption of animal products may contribute to elevated prenatal PFAS levels.

Exposure to perfluoroalkyl substances in early pregnancy and the risk of hypertensive disorders of pregnancy: A nested case-control study in Guangxi, China

12 Oct 2021 | Chemosphere

PFAS mixtures as well as PFOA and PFOS exposure was associated with an increased risk of developing potentially fatal disorders in mother and child.

Per- and polyfluoroalkyl substances in the atmospheric total suspended particles in Karachi, Pakistan: Profiles, potential sources, and daily intake estimates

12 Oct 2021 | Chemosphere

Data suggested that northwestern Pakistan and western Afghanistan areas were highly associated with the long-range atmospheric transport of PFAS.

Information Requirements under the Essential-Use Concept: PFAS Case Studies

11 Oct 2021 | Environ Sci Technol

An investigation into how much information is available on the types and functions of PFAS in specific uses, how much information is available on alternatives, their performance and hazardous properties, and whether this information is sufficient as a basis for deciding on the essentiality of a PFAS use, was conducted.

Exposure routes, bioaccumulation and toxic effects of per- and polyfluoroalkyl substances (PFASs) on plants: A critical review

6 Oct 2021 | Environ Int

PFAS exposure damages plant cell structure and organelle functions.

Per- and Polyfluoroalkyl Substances (PFAS) in Street Sweepings

5 Oct 2021 | Environ Sci Technol

In different cities, the dominant PFAS by concentration and frequency of detection varied; however, PFOA and linear PFOS were the two PFAS that were detected the most frequently.