Environmental exposure to low-dose perfluorohexanesulfonate promotes obesity and non-alcoholic fatty liver disease in mice fed a high-fat diet

7 Mar 2022 | Environ Sci Pollut Res Int

Environmental PFHxS exposure is a likely risk factor for metabolic diseases such as non-alcoholic fatty liver disease, especially among obese individuals.

An Outdoor Aging Study to Investigate the Release of Per- And Polyfluoroalkyl Substances (PFAS) from Functional Textiles

28 Feb 2022 | ES&T

Each side-chain fluorinated polymer containing textile finish emitted a distinct pattern following weathering, and in some cases, the concentrations exceeded regulatory limits for textiles.

[Invited Perspective] Current Breast Milk PFAS Levels in the United States and Canada Indicate Need for Additional Monitoring and Actions to Reduce Maternal Exposures

28 Feb 2022

Addressing the higher breast milk concentrations from maternal exposure to PFAS in drinking water will require identifying contaminated drinking water sources and establishing health-protective PFAS drinking water guidelines that consider both exposures and risks to breastfed infants.

Comparative Toxicity of Aquatic PFAS Exposure in Three Species of Amphibians

28 Feb 2022 | Environ Toxicol Chem

Chronic exposure to PFOS, PFOA, PFHxS, and 6:2 FTS can negatively affect amphibian body condition and development at low concentrations.

Current Breast Milk PFAS Levels in the United States and Canada: After All This Time, Why Don't We Know More?

28 Feb 2022 | Environ Health Perspect

The authors emphasize the need to study PFAS in breast milk and found that all average estimated and measured breast milk PFOA and PFOS concentrations exceeded drinking water screening values for children, sometimes by more than two orders of magnitude.

Maternal Perfluorinated Compound Exposure and Risk of Early Pregnancy Loss: A Nested Case-control Study

28 Feb 2022 | Biomed Environ Sci

Higher maternal serum concentrations of PFDA and PFUdA were associated with an elevated risk of early pregnancy loss within 12 weeks of gestation.

Association between maternal per- and polyfluoroalkyl substance exposure and newborn telomere length: Effect modification by birth seasons

28 Feb 2022 | Environ Int

A higher maternal PFOA concentration was significantly associated with shorter newborn telomere length in spring-born infants but not in those born in other seasons.

Early Warnings by Liver Organoids on Short- and Long-Chain PFAS Toxicity

28 Feb 2022 | Toxics

Short-chain PFAS were found to reduce the structural integrity and disrupt normal cell functions in a synthetic tissue model.

Evaluation and validation of methodologies for the extraction of per- and polyfluoroalkyl substances (PFASs) in serum of birds and mammals

28 Feb 2022 | Anal Bioanal Chem

Protein precipitation and enhanced matrix removal were found to be fast and effective methodologies for the extraction of PFAS from low volumes of serum.

From cohorts to molecules: Adverse impacts of endocrine disrupting mixtures

21 Feb 2022 | Science

A mixture of endocrine-disrupting chemicals identified in pregnant women, including PFAS, phthalates, and BPA, were found to cause abnormalities in two model organisms and may also be associated with language delay in humans.

Enhancing Scientific Support for the Stockholm Convention’s Implementation: An Analysis of Policy Needs for Scientific Evidence

21 Feb 2022 | ES&T

Scientists discuss the success of the Stockholm Convention for addressing global threats of PFAS and provide guidance for further support of the Convention.

Utilizing Pine Needles to Temporally and Spatially Profile Per- and Polyfluoroalkyl Substances (PFAS)

21 Feb 2022 | Environ Sci Technol

Non-targeted analysis of archived and new pine needle samples revealed over 70 PFAS, including both legacy PFAAs and their emerging replacements such as chlorinated derivatives, ultrashort chain PFAS, perfluoroalkyl ether acids, and more.

Spatial distribution and load of per- and polyfluoroalkyl substances (PFAS) in background soils in Sweden

21 Feb 2022 | Chemosphere

Sixteen out of 28 measured PFAS were detected in forest soils across Sweden with concentrations of PFOS explained by population density. The estimated total PFAS sink in soil throughout Sweden was on the order of several tons.

Risk of Cancer in a Community Exposed to Per- and Poly-Fluoroalkyl Substances

20 Feb 2022 | Environ Health Insights

Merrimack residents experienced a significantly higher risk of at least 4 types of cancer between 2005 and 2014 which may be linked to PFAS-contaminated drinking water.

Insights into the effects of salinity on the sorption and desorption of legacy and emerging per-and polyfluoroalkyl substances (PFASs) on marine sediments

16 Feb 2022 | Environ Pollut

The desorption rate of PFAS from marine sediment decreases with increased perfluorocarbon chain length of PFAS and increased sediment salinity.