PFAS and potential adverse impacts on bone and adipose tissue through interactions with PPAR-gamma
8 Sep 2021 | Endocrinology
PFAS was found to affect cell differentiation and bone development in several human model species.
Associations between polyfluoroalkyl substance and organophosphate flame retardant exposures and telomere length in a cohort of women firefighters and office workers in San Francisco
7 Sep 2021 | Environ Health
Positive associations between PFAS and telomere length in women workers, with larger effects seen among firefighters as compared to office workers.
Hexafluoropropylene oxide dimer acid (HFPO-DA) induced developmental cardiotoxicity and hepatotoxicity in hatchling chickens: Roles of peroxisome proliferator activated receptor alpha
4 Sep 2021 | Environ Pollut
Exposure to HFPO-DA induced developmental cardio-toxicity and hepatotoxicity in hatchling chickens similar to PFOA
The Nrf2a pathway impacts zebrafish offspring development with maternal preconception exposure to perfluorobutanesulfonic acid
2 Sep 2021 | Chemosphere
PFBS exposures were found to alter egg and embryo development, when exposure occurs preconception.
Per/polyfluoroalkyl substances production, applications and environmental impacts
31 Aug 2021 | Bioresource Tech.
Current chemical and biological remediation technologies are expensive/not effective and thus new remediation technologies must be developed.
Early-life exposure to perfluoroalkyl substances in relation to serum adipokines in a longitudinal birth cohort
31 Aug 2021 | Environ Res
Childhood concentrations of PFASs were associated with decreased regulation of appetite and fat storage.
Exposure to hexafluoropropylene oxide dimer acid (HFPO-DA) disturbs the gut barrier function and gut microbiota in mice
31 Aug 2021 | Environ Pollut
Potential gut toxicity of HFPO-DA and is perceived as a major problem of health risk that affects inflammation, gut barrier dysfunction, and gut microbiota disturbance in mammals.
Understanding the Impact of Perfluorinated Compounds on Cardiovascular Diseases and Their Risk Factors: A Meta-Analysis Study
31 Aug 2021 | Int J Environ Res Public Health
PFOA and PFOS were positively associated with developing cardiovascular diseases and their risk factors.
Rapid Determination of Per- and Polyfluoroalkyl Substances (PFAS) in Harbour Porpoise Liver Tissue by HybridSPE-UPLC-MS/MS
31 Aug 2021 | Toxics
A new analytical method was optimized for use on mammalian tissues with up to 89% detection.
Exposure to GenX and Its Novel Analogs Disrupts Hepatic Bile Acid Metabolism in Male Mice
31 Aug 2021 | Environ Sci Technol
The inhibition of nutrient absorption may be a prominent adverse effect induced by exposure to GenX, its analogs, and PFOA.
Analysis of per- and poly-fluoroalkyl substances (PFAS) in processed foods from FDA's Total Diet Study
31 Aug 2021 | Anal Bioanal Chem
PFAS features detected by LC-MS/MS correlated well in abundance with LC-IMS-MS data; however, LC-IMS-MS identified a number of additional PFAS, many known to be components of firefighting foams.
Early pregnancy loss: Do Per- and polyfluoroalkyl substances matter?
31 Aug 2021 | Environ Int
Overall, we suggest that most PFAS were not associated with early pregnancy loss at the current exposure levels.
Perfluorobutanoic acid (PFBA): No high-level accumulation in human lung and kidney tissue
30 Aug 2021 | Int J Hyg Environ Health
Contrary to previous findings, analysis of short-chain PFAS in human lungs and kidney indicates PFBA is not likely to accumulate in these tissues.
The occurrence of per- and polyfluoroalkyl substances (PFASs) in fluoropolymer raw materials and products made in China
25 Aug 2021 | J Environ Sci (China)
Generally, the levels of PFOA in raw materials were higher than in products, implying that PFOA in the emulsion/dispersion resin could be partly removed during the polymerization or post-processing steps.
Occurrence of perfluoroalkyl substances (PFASs) in marine plastic litter from coastal areas of Central Chile
25 Aug 2021 | Mar Pollut Bull
Long-chain PFAS, which can be metabolically degraded into PFOS, were found on six South American beaches in plastic debris.