Per- and Poly-fluoroalkyl Substances (PFAS) and Female Reproductive Outcomes: PFAS Elimination, Endocrine-Mediated Effects, and Disease

30 Nov 2021 | Toxicology

A summary of the role of PFAS in female reproductive dysfunction and disease is presented with the major data gaps, highlighting the importance for further study of the action mechanisms of PFAS harm in women.

Tumor and serum levels of per- and polyfluoroalkyl (PFAS) in hepatobiliary and gastrointestinal malignancy

30 Nov 2021 | Am J Surg

Cancer patients had higher levels of PFOS than the national average and those with higher blood serum levels of PFOS were more likely to have higher levels of PFOS in tumors.

Uptake of perfluoroalkyl substances, pharmaceuticals, and parabens by oyster mushrooms (Pleurotus ostreatus) and exposure risk in human consumption

24 Nov 2021 | Chemosphere

Uptake of PFAS by oyster mushrooms was negatively correlated with perfluorocarbon chain length, and mushrooms grown in soil contaminated by PFAS may pose a risk if consumed.

Thermal processing reduces PFAS concentrations in blue food – A systematic review and meta-analysis

23 Nov 2021 | EcoEvoRxiv

Initial recommendations were developed to reduce PFAS in fish via cooking using common kitchen items and cooking techniques.

Surface-water/groundwater boundaries affect seasonal PFAS concentrations and PFAA precursor transformations

23 Nov 2021 | Environ Sci Process Impacts

Natural biogeochemical fluctuations associated with surface-water and groundwater boundaries may lead to PFAA precursor loss and seasonal variations in PFAA concentrations.

Impairment of human dopaminergic neurons at different developmental stages by perfluoro-octanoic acid (PFOA) and differential human brain areas accumulation of perfluoroalkyl chemicals

23 Nov 2021 | Environ Int

In a proof-of-concept study, PFOA exposure was found to disrupt the most sensitive stage of neuron development.

Perfluorooctane sulfonate (PFOS) induces several behavioural defects in Caenorhabditis elegans that can also be transferred to the next generations

23 Nov 2021 | Chemosphere

PFOS can exert severe neurobehavioral defects in locomotion, lifespan, and reproduction that can be transferred from parents to their offspring in a human model species.

Per- and Polyfluoroalkyl Substances (PFAS): Significance and Considerations within the Regulatory Framework of the USA

23 Nov 2021 | Int J Environ Res Public Health

Regulatory agencies must start being proactive instead of reactive with PFAS contamination.

Immunotoxicity mechanisms of perfluorinated compounds PFOA and PFOS

23 Nov 2021 | Chemosphere

Mechanisms of PFOA and PFOS immunotoxicity in humans and animals were summarized.

What difference can drop-in substitution actually make? A life cycle assessment of alternative water repellent chemicals

22 Nov 2021 | J. Clean. Prod.

A life cycle assessment found non-fluorinated durable water repellents for outdoor garments were environmentally preferable to fluorinated variants leading to the recommendation to phase out PFAS.

Per- and polyfluoroalkyl substances (PFASs) in airborne particulate matter (PM2.0) emitted during floor waxing: A pilot study

16 Nov 2021 | Atmos. Environ.

Significantly higher levels of PFAS were measured during floor waxing, potentially putting occupational workers at greater risk.

Biodegradation of per- and polyfluoroalkyl substances (PFAS): A review

16 Nov 2021 | Bioresour Technol

The biodegradation pathways for different types of subclasses of PFAS are summarized in two major categories, biodegradation with and without the cleavage of the C-F bond.

A New OECD Definition for Per- and Polyfluoroalkyl Substances

16 Nov 2021 | Environ Sci Technol

The Organisation for Economic Co-operation and Development and the United Nations Environment Programme expanded on their definition of PFAS to include fluorinated substances that contain at least one fully fluorinated methyl or methylene carbon atom.

Investigation of levels of perfluoroalkyl substances in freshwater fishes collected in a contaminated area of Veneto Region, Italy

16 Nov 2021 | Environ Sci Pollut Res Int

Consumption of fish more than once a month from a contaminated region of Italy might result in high exposure to PFAS.