Showing 31-45 of 1022
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Changes in Concentrations of Polyfluoroalkyl Substances in Human Milk Over Lactation Time and Effects of Maternal Exposure via Analysis of Matched Samples
Science
23 Feb 2024 | Environ. Sci. Technol.
Breast milk samples from 76 women post-delivery found certain PFAS compounds, particularly PFOA, PFOS, and N-MeFOSAA, with N-MeFOSAA being the highest in human milk at 3 months, suggesting an increase in PFAS concentrations in milk samples over time.
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PFAS River Export Analysis Highlights the Urgent Need for Catchment-Scale Mass Loading Data
Science
19 Feb 2024 | ES&T Letters
A study of a European river system found that wastewater treatment works contribute significantly to the total PFAS levels exported from the river, but that additional PFAS sources must also be eliminated in order to meet water quality improvement goals.
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Reproductive toxicity of PFOA, PFOS and their substitutes: A review based on epidemiological and toxicological evidence
Science
17 Feb 2024 | Environ Res
PFAS are widely recognized for their reproductive toxicity, with substitutes proving equally or more harmful; this review covers potential reproductive toxicity mechanisms for PFAS in both males and females.
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Associations of per- and polyfluoroalkyl substances with maternal metabolic and inflammatory biomarkers in early-to-mid-pregnancy
Science
10 Feb 2024 | Environ Res
Exposure to PFAS during early-to-mid pregnancy was associated with decreased insulin levels, increased HDL cholesterol, and alterations in inflammatory markers, suggesting potential metabolic and inflammatory disruptions that may impact maternal and fetal health.
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Associations of dietary intake and longitudinal measures of per- and polyfluoroalkyl substances (PFAS) in predominantly Hispanic young Adults: A multicohort study
Science
27 Jan 2024 | Environ Int
Dietary factors, such as tea & pork intake and eating food not prepared at home, were associated with increases in blood levels of PFAS in young Hispanic adults, underscoring the significance of diet in PFAS exposure and the need for monitoring food and beverage contamination.
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Profiling research on PFAS in wildlife: Systematic evidence map and bibliometric analysis
Science
24 Jan 2024 | Ecol. solut. evid.
A comprehensive review of over 580 publications on PFAS in wildlife identified a linear increase in research from 2001 to 2021 covering 1042 species from 26 taxonomic classes, and emphasized the need for further exploration of new-generation PFAS, assessment in mid- and low-income countries, and more long-term studies.
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Association between per- and polyfluoroalkyl substances and sex hormone levels in males based on human studies
Science
22 Jan 2024 | Ecotoxicol Environ Saf
In a meta-analysis of 12 studies involving 7506 participants, exposure to PFNA and PFOA was found to be negatively correlated with male testosterone levels, emphasizing the need to consider these chemicals as potential risk factors for male reproductive health.
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Tree barks for retrospective measurement and source appointment of airborne perfluoroalkyl and polyfluoroalkyl substances
Science
16 Jan 2024 | Environ. Pollut.
Tree bark was found to be a valuable bioindicator for assessing airborne PFAS pollution, offering a long-term perspective on historical PFAS emissions and allowing for the characterization and tracking of sources, as demonstrated in a study of eight cities in southern Jiangsu Province, China.
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Association of prenatal exposure to perfluorinated and polyfluoroalkyl substances with childhood neurodevelopment: A systematic review and meta-analysis
Science
10 Jan 2024 | Ecotoxicol Environ Saf
A meta-analysis on prenatal exposure to PFAS suggests a sex-specific relationship, revealing that PFOS, PFOA, and PFHxS are associated with decreased performance IQ in boys but PFOS was linked to increased performance IQ in girls, while PFAS are linked to executive function impairments in children without a significant association with behavioral difficulties.
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Toxicity Assessment of Mixed Exposure of Nine Perfluoroalkyl Substances at Concentrations Relevant to Daily Intake
Science
10 Jan 2024 | Toxics
This study exposed mice to a mixture of PFAS at levels equivalent to estimated daily human intake, revealing that even low concentrations of PFAS caused liver tissue changes and altered gene expression related to metabolism and cancer, emphasizing the need for thorough toxicity assessments of these persistent environmental contaminants.
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Occurrence of Major Perfluorinated Alkylate Substances in Human Blood and Target Organs
Science
28 Dec 2023 | Environ Sci Technol
PFAS levels in the liver correlated well with other organs, supporting the use of blood concentrations as a measure of PFAS exposure and suggesting the liver as the primary organ of PFAS retention, with minor variations observed in other organs.
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Per-and poly-fluoroalkyl substances (PFAS) exposure is associated with later occurrence of inflammatory bowel disease
Science
27 Dec 2023 | CGH
A connection was found between elevated PFAS levels and increased odds of Crohn’s disease and ulcerative colitis for up to 10 years prior to diagnosis, with both legacy and emerging PFAS chemicals implicated.
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GenX Disturbs the Indicators of Hepatic Lipid Metabolism Even at Environmental Concentration in Drinking Water via PPARα Signaling Pathways
Science
27 Dec 2023 | Chem Res Toxicol
GenX, a substitute for PFOA, was found to cause liver damage and disrupt lipid metabolism in mice even at low environmental concentrations when exposed to drinking water.
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First insights into per-and polyfluoroalkyl substance contamination in edible fish species of the Indus water system of Pakistan
Science
17 Dec 2023 | Chemosphere
The study investigated the contamination of edible fish in major tributaries of the Indus System andfound high levels of PFAS, in certain fish species from areas with poor wastewater treatment in Pakistan, highlighting potential environmental and health concerns, and suggesting the need for ongoing monitoring and research into the bioaccumulation patterns of PFAS.
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[Press Release] Dingell, Fitzpatrick, Ryan Introduce PFAS Action Act
Policy
14 Dec 2023
Representatives Debbie Dingell, Brian Fitzpatrick, and Pat Ryan, along with 13 additional members of Congress, introduced comprehensive, bipartisan legislation to protect Americans and the environment from harmful forever chemicals known as PFAS.