Showing 571-585 of 2162
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Association of prenatal exposure to perfluorinated and polyfluoroalkyl substances with childhood neurodevelopment: A systematic review and meta-analysis
Science
10 Jan 2024 | Ecotoxicol Environ Saf
A meta-analysis on prenatal exposure to PFAS suggests a sex-specific relationship, revealing that PFOS, PFOA, and PFHxS are associated with decreased performance IQ in boys but PFOS was linked to increased performance IQ in girls, while PFAS are linked to executive function impairments in children without a significant association with behavioral difficulties.
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Toxicity Assessment of Mixed Exposure of Nine Perfluoroalkyl Substances at Concentrations Relevant to Daily Intake
Science
10 Jan 2024 | Toxics
This study exposed mice to a mixture of PFAS at levels equivalent to estimated daily human intake, revealing that even low concentrations of PFAS caused liver tissue changes and altered gene expression related to metabolism and cancer, emphasizing the need for thorough toxicity assessments of these persistent environmental contaminants.
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PFAS found in almost 1,000 products sold in Maine, so far
News
4 Jan 2024 | Portland Press Herald
From shampoo to school supplies, dog treats to dishware, the brand names that admit to using forever chemicals are ubiquitous.
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Assessing potential human health and ecological implications of PFAS from leave-in dental products
Science
3 Jan 2024 | Toxicol Ind Health
PFBA and PFOS were found in low levels in night guards with no detection in whitening trays, suggesting these dental products are unlikely to pose health concerns or contribute significantly to environmental PFAS exposure compared to exposure from food and water.
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Binding of Per- and Polyfluoroalkyl Substances (PFAS) to Serum Proteins: Implications for Toxicokinetics in Humans
Science
3 Jan 2024 | Environ Sci Technol
PFAS binding to major blood serum proteins is thought to affect toxicity, transport, and half-lives in the body. This study found shorter-chain PFAS showing a stronger binding to human serum albumin and longer-chain PFAS displaying a greater affinity for globulins, emphasizing the significance of understanding these interactions for more precise assessments of PFAS impact on human health in epidemiological studies.
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Overview of PFAS Regulations in the United States and What Japanese Companies and Their U.S. Subsidiaries Need to Know
Policy
2 Jan 2024
This article provides an overview of PFAS regulation in the United States, emphasizing its relevance to various Japanese businesses, including those in specialty chemicals, manufacturing, oil and gas, and trading, due to the widespread use of PFAS in commercial products, potential liability risks, and recent multi-billion dollar settlements in PFAS contamination lawsuits.
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Investigating the progression of preeclampsia through a comprehensive analysis of genes associated with per- and polyfluoroalkyl substances
Science
2 Jan 2024 | Toxicol Mech Methods
Using advanced analysis of genetic data, researchers identified a potential link between PFAS and the risk of preeclampsia, suggesting that these environmental factors may play a role in the development of the disease, and highlighted six genes with diagnostic potential for preeclampsia.
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Understanding the effects of per- and polyfluoroalkyl substances on early skin development: Role of ciliogenesis inhibition and altered microtubule dynamics
Science
30 Dec 2023 | Sci Total Environ
Exposure to PFOS may disrupt early skin development by altering cell morphology, gene expression, and crucial signaling pathways, suggesting a potential link between PFAS exposure and congenital skin diseases during embryonic development.
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‘Forever chemicals’ found in freshwater fish, yet most states don’t warn residents
News
29 Dec 2023 | Brudge Michigan
With no federal guidance, what is considered safe to eat varies significantly among states, most of which provide no regulation.
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Firefighter's Cancer Leads Wife to Discovery of Toxic Gear Killing Heroes Across U.S.: ‘It’s Infuriating’
News
27 Dec 2023 | People
Since 2002 cancer has been responsible for the deaths of almost two out of every three firefighters, according to the International Association of Fire Fighters.
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Inside the Pentagon's Painfully Slow Effort to Clean Up Decades of PFAS Contamination
News
27 Dec 2023 | Military.com
Thirteen years later, the community is still waiting on whatever it will take to clean its water. As a result of dogged activism and pressure from government officials, the Air Force has finally taken initial steps simply to contain the chemicals.
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GenX Disturbs the Indicators of Hepatic Lipid Metabolism Even at Environmental Concentration in Drinking Water via PPARα Signaling Pathways
Science
27 Dec 2023 | Chem Res Toxicol
GenX, a substitute for PFOA, was found to cause liver damage and disrupt lipid metabolism in mice even at low environmental concentrations when exposed to drinking water.
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Prenatal Exposure to Poly- and Perfluoroalkyl Substances (2009-2014) and Vaccine Antibody Titers of Measles, Mumps, Rubella, and Varicella in Children Four to Eight Years Old from the Healthy Start Cohort
Science
26 Dec 2023 | Environ Health Perspect
Prenatal exposure to PFAS is linked to lower antibody levels in fully immunized children, particularly for measles and mumps, suggesting potential immunotoxic effects.
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Invited Perspective. Per- and Polyfluoroalkyl Substances, Hepatotoxicity, and Liver Disease: Evidence and Clinical Responses
Science
25 Dec 2023 | Medical Research Archives
This perspective outlines PFAS hepatoxicity, suggesting practical clinician responses to address patient and community needs, and emphasizing strong evidence of PFAS causing adverse changes in human liver biomarkers.
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Comparison of the PFAS and physical-chemical parameter fluctuations between an ash landfill and a MSW landfill
Science
22 Dec 2023 | Waste Manag
PFAS levels in municipal solid waste and incinerator ash landfillswere found to be higher in solid waste leachate, suggesting the importance of considering these differences when designing leachate management systems for different landfill types.