Showing 1336-1350 of 1774
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The use of in vitro methods in assessing human health risks associated with short-chain perfluoroalkyl and polyfluoroalkyl substances (PFAS)
Science
13 Dec 2021 | J Appl Toxicol
This review summarizes the PFAS toxicity data obtained using human cells in vitro, discusses the advantages and limitations of cell-based models, and provides thoughts on potential solutions to the challenges of these methods.
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PFOA induces alteration in DNA methylation regulators and SARS-CoV-2 targets and in mouse lung tissues
Science
12 Dec 2021 | Toxicol Rep
PFOA was found to change gene expression in lungs, potentially increasing susceptibility to COVID-19.
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[Press Release] Chemical companies tout green credentials whilst developing hazardous chemicals behind closed doors
News
9 Dec 2021 | ChemSec
Chemical companies around the world are actively marketing their greener, more sustainable products, whilst holding back details on the mass production of hazardous chemicals, ChemSec’s ranking of chemical companies reveals today.
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Per- and Poly-fluoroalkyl Substances (PFAS) and Female Reproductive Outcomes: PFAS Elimination, Endocrine-Mediated Effects, and Disease
Science
30 Nov 2021 | Toxicology
A summary of the role of PFAS in female reproductive dysfunction and disease is presented with the major data gaps, highlighting the importance for further study of the action mechanisms of PFAS harm in women.
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Uptake of perfluoroalkyl substances, pharmaceuticals, and parabens by oyster mushrooms (Pleurotus ostreatus) and exposure risk in human consumption
Science
24 Nov 2021 | Chemosphere
Uptake of PFAS by oyster mushrooms was negatively correlated with perfluorocarbon chain length, and mushrooms grown in soil contaminated by PFAS may pose a risk if consumed.
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Legislation to Protect Public Health and the Environment from PFAS
Policy
16 Nov 2021
Several state attorneys generals write to urge a U.S. Congressional Committee to pass legislation that ensures that PFAS contamination is addressed.
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Perfluorooctane sulfonate (PFOS) triggers migration and invasion of esophageal squamous cell carcinoma cells via regulation of Zeb1
Science
9 Nov 2021 | Drug Chem Toxicol
Environmental exposure and body accumulation of PFOS might be an important risk factor for esophagus cancer progression, one of the most deadly cancers worldwide.
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Engineering human liver fatty acid binding protein for detection of poly- and perfluoroalkyl substances
Science
9 Nov 2021 | Biotechnol Bioeng
A novel method of detecting selected PFAS in water (at parts per billion or million levels) by using human liver proteins was developed and implemented in field applications.
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Emerging investigator series: human CYP2A6 catalyzes the oxidation of 6:2 fluorotelomer alcohol
Science
9 Nov 2021 | Environ Sci Process Impacts
An enzyme was found to play an important role in the indirect human exposure to bioactive and persistent PFCAs which are metabolites of 6:2 fluorotelomer alcohol.
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Stability of Per- and Polyfluoroalkyl Substances in Solvents Relevant to Environmental and Toxicological Analysis
Science
9 Nov 2021 | Environ Sci Technol
Common solvents were found to degrade PFAS during chemical analysis, potentially corrupting results.
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Exposure to perfluoroalkyl substances in waste recycling workers: Distributions in paired human serum and urine
Science
9 Nov 2021 | Environ Int
The results of this study suggest that sorters at recycling facilities may be directly exposed to PFAS and is the first to detect PFPAs in human urine.
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Millions consuming 'invisible toxic cocktail' of cancer-linked chemicals: study
News
3 Nov 2021 | The Hill
Millions of Americans are unknowingly ingesting water that includes “an invisible toxic cocktail” of cancer-linked chemicals, a new survey of the nation’s tap water has found.
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Analytical uncertainties in a longitudinal study - A case study assessing serum levels of per- and poly-fluoroalkyl substances (PFAS)
Science
2 Nov 2021
PFAA precursors were most likely to be the primary contaminant in AFFF-impacted surface soils.
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Detection of long chain per- and polyfluoroalkyl substances (PFAS) in the benthic Golden tilefish (Lopholatilus chamaeleonticeps) and their association with microscopic hepatic changes
Science
2 Nov 2021 | Sci Total Environ
PFAS exposure was found to be possibly detrimental to bottom-dwelling aquatic species.
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Analytical uncertainties in a longitudinal study - A case study assessing serum levels of per- and poly-fluoroalkyl substances (PFAS)
Science
2 Nov 2021 | Int J Hyg Environ Health
The variance between sample collection was found to be an important consideration affecting long-term PFAS studies.