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Toxicity Assessment of Mixed Exposure of Nine Perfluoroalkyl Substances at Concentrations Relevant to Daily Intake
Science
10 Jan 2024 | Toxics
This study exposed mice to a mixture of PFAS at levels equivalent to estimated daily human intake, revealing that even low concentrations of PFAS caused liver tissue changes and altered gene expression related to metabolism and cancer, emphasizing the need for thorough toxicity assessments of these persistent environmental contaminants.
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Association of prenatal exposure to perfluorinated and polyfluoroalkyl substances with childhood neurodevelopment: A systematic review and meta-analysis
Science
10 Jan 2024 | Ecotoxicol Environ Saf
A meta-analysis on prenatal exposure to PFAS suggests a sex-specific relationship, revealing that PFOS, PFOA, and PFHxS are associated with decreased performance IQ in boys but PFOS was linked to increased performance IQ in girls, while PFAS are linked to executive function impairments in children without a significant association with behavioral difficulties.
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The race to destroy the toxic ‘forever chemicals’ polluting our world
News
8 Jan 2024 | The Guardian
As countries work to ban more and more PFAS, focus is shifting to how to remove the ones already out there.
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Maine Begins PFAS Essential Use ID Process to Permit Sales
Policy
8 Jan 2024
Companies and industrial sectors that claim PFAS are essential for the goods they produce have until March 1 to notify a Maine agency as the first step to help continue selling those products in the state.
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[Report] Rewind And (P)FASt Forward: Current Developments In PFAS Regulation
Policy
8 Jan 2024
This report summarizes these and other major PFAS regulatory developments from 2023 and forecasts what 2024 may have in store.
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Navigating the changing landscape of PFAS regulations
News
8 Jan 2024 | The Insurer
Navigating the complexities of these regulations requires a proactive approach, including internal risk assessments, documentation, strategic planning, and risk transfer where possible.
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PFAS found in almost 1,000 products sold in Maine, so far
News
4 Jan 2024 | Portland Press Herald
From shampoo to school supplies, dog treats to dishware, the brand names that admit to using forever chemicals are ubiquitous.
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Binding of Per- and Polyfluoroalkyl Substances (PFAS) to Serum Proteins: Implications for Toxicokinetics in Humans
Science
3 Jan 2024 | Environ Sci Technol
PFAS binding to major blood serum proteins is thought to affect toxicity, transport, and half-lives in the body. This study found shorter-chain PFAS showing a stronger binding to human serum albumin and longer-chain PFAS displaying a greater affinity for globulins, emphasizing the significance of understanding these interactions for more precise assessments of PFAS impact on human health in epidemiological studies.
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Assessing potential human health and ecological implications of PFAS from leave-in dental products
Science
3 Jan 2024 | Toxicol Ind Health
PFBA and PFOS were found in low levels in night guards with no detection in whitening trays, suggesting these dental products are unlikely to pose health concerns or contribute significantly to environmental PFAS exposure compared to exposure from food and water.
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Overview of PFAS Regulations in the United States and What Japanese Companies and Their U.S. Subsidiaries Need to Know
Policy
2 Jan 2024
This article provides an overview of PFAS regulation in the United States, emphasizing its relevance to various Japanese businesses, including those in specialty chemicals, manufacturing, oil and gas, and trading, due to the widespread use of PFAS in commercial products, potential liability risks, and recent multi-billion dollar settlements in PFAS contamination lawsuits.
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Investigating the progression of preeclampsia through a comprehensive analysis of genes associated with per- and polyfluoroalkyl substances
Science
2 Jan 2024 | Toxicol Mech Methods
Using advanced analysis of genetic data, researchers identified a potential link between PFAS and the risk of preeclampsia, suggesting that these environmental factors may play a role in the development of the disease, and highlighted six genes with diagnostic potential for preeclampsia.
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‘I’ve been drinking poison for 30 years’: West Plains residents reckon with slow-moving PFAS cleanup
News
31 Dec 2023 | The Columbian
“My emotions have been on a roller coaster for the last couple of months. Anger. Disappointment. Verging on heartbreak,” Danner said in a mid-December interview. “I’ve been drinking poison for 30 years and there’s nothing going to be done about it anytime soon.”
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Understanding the effects of per- and polyfluoroalkyl substances on early skin development: Role of ciliogenesis inhibition and altered microtubule dynamics
Science
30 Dec 2023 | Sci Total Environ
Exposure to PFOS may disrupt early skin development by altering cell morphology, gene expression, and crucial signaling pathways, suggesting a potential link between PFAS exposure and congenital skin diseases during embryonic development.
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‘Forever chemicals’ found in freshwater fish, yet most states don’t warn residents
News
29 Dec 2023 | Brudge Michigan
With no federal guidance, what is considered safe to eat varies significantly among states, most of which provide no regulation.
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‘Forever chemicals’ were everywhere in 2023. Expect more litigation in 2024
News
28 Dec 2023 | Reuters
Lawsuits accusing major chemical companies of polluting U.S. drinking water with toxic PFAS chemicals led to over $11 billion in settlements in 2023, with experts predicting that new federal regulations and a growing awareness of the breadth of PFAS contamination in the U.S. will spur more litigation and settlements in the year ahead.