Showing 226-240 of 518
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Bovine oocyte exposure to perfluorohexane sulfonate (PFHxS) induces phenotypic, transcriptomic, and DNA methylation changes in resulting embryos in vitro
Science
15 Mar 2022 | Reproductive Toxicology
PFHxS was found to induce morphological and molecular changes in developing cow reproductive cells at critical stages.
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Systematic Developmental Toxicity Assessment of a Structurally Diverse Library of PFAS in Zebrafish
Science
15 Mar 2022 | J. Hazard. Mater.
Exposure to 49 of 139 PFAS affected zebrafish development with low PFAS volatility associated with developmental toxicity.
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Environmental exposure to low-dose perfluorohexanesulfonate promotes obesity and non-alcoholic fatty liver disease in mice fed a high-fat diet
Science
7 Mar 2022 | Environ Sci Pollut Res Int
Environmental PFHxS exposure is a likely risk factor for metabolic diseases such as non-alcoholic fatty liver disease, especially among obese individuals.
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Maternal Perfluorinated Compound Exposure and Risk of Early Pregnancy Loss: A Nested Case-control Study
Science
28 Feb 2022 | Biomed Environ Sci
Higher maternal serum concentrations of PFDA and PFUdA were associated with an elevated risk of early pregnancy loss within 12 weeks of gestation.
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Early Warnings by Liver Organoids on Short- and Long-Chain PFAS Toxicity
Science
28 Feb 2022 | Toxics
Short-chain PFAS were found to reduce the structural integrity and disrupt normal cell functions in a synthetic tissue model.
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Enhancing Scientific Support for the Stockholm Convention’s Implementation: An Analysis of Policy Needs for Scientific Evidence
Policy
21 Feb 2022
Scientists discuss the success of the Stockholm Convention for addressing global threats of PFAS and provide guidance for further support of the Convention.
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From cohorts to molecules: Adverse impacts of endocrine disrupting mixtures
Science
21 Feb 2022 | Science
A mixture of endocrine-disrupting chemicals identified in pregnant women, including PFAS, phthalates, and BPA, were found to cause abnormalities in two model organisms and may also be associated with language delay in humans.
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Enhancing Scientific Support for the Stockholm Convention’s Implementation: An Analysis of Policy Needs for Scientific Evidence
Science
21 Feb 2022 | ES&T
Scientists discuss the success of the Stockholm Convention for addressing global threats of PFAS and provide guidance for further support of the Convention.
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Risk of Cancer in a Community Exposed to Per- and Poly-Fluoroalkyl Substances
Science
20 Feb 2022 | Environ Health Insights
Merrimack residents experienced a significantly higher risk of at least 4 types of cancer between 2005 and 2014 which may be linked to PFAS-contaminated drinking water.
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Prenatal exposure to toxics risks delay of child’s brain development
News
18 Feb 2022 | Environmental Health News
Everyday levels of a pregnant woman’s exposure to mixtures of endocrine-disrupting chemicals like BPA, phthalates, and PFAS, put their child at an increased risk of delayed language development, according to new research.
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Firefighters’ Catch-22: Protective gear full of carcinogens
News
16 Feb 2022 | E&E News
Firefighters are exposed to cancer-causing chemicals in the very clothing and gear that is meant to protect them, a paradox that stems from standards set under industry influence.
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Concentrations of per- and polyfluoroalkyl substances (PFAS) in human placental tissues and associations with birth outcomes
Science
15 Feb 2022 | Chemosphere
All tested placenta samples contained detectable PFAS, including PFOS, PFOA, PFNA, and PFDA in >96% samples, and placental PFOS was associated with lower birth weight for in male infants and higher birth weight in female infants.
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Human exposure to F-53B in China and the evaluation of its potential toxicity: An overview
Science
15 Feb 2022 | Environ Int
A review of a novel PFAS demonstrated hepatotoxicity, endocrine disruption, reproductive, and developmental toxicity, and suggested further research given the extreme biopersistence of F-53B.
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Per- and polyfluoroalkyl substances in the environment
Science
7 Feb 2022 | Science
This review summarizes the sources, transport, degradation, and toxicological implications of the megatonne of PFAS produced yearly, highlighting the importance of investigating potential PFAS replacements, the importance of lifecycle considerations, and that PFAS remediation efforts are still in their infancy.
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Prenatal Exposure to Per- and Polyfluoroalkyl Substances and Facial Features at 5 Years of Age: A Study from the Danish National Birth Cohort
Science
1 Feb 2022 | Environ Health Perspect
Prenatal PFAS exposure might influence the development of fetus heads and faces, especially when coupled with alcohol consumption.