Occurrence and pattern of legacy and emerging per-and Poly-FluoroAlkyl substances (PFAS) in eggs of loggerhead turtle Caretta caretta from western Mediterranean
22 Jan 2024 | Environ. Pollut.
Many PFAS were found in loggerhead turtle eggs off the coast of Italy, including emerging PFAS, and the highest concentrations in some eggs may be due to fluoropolymer-based marine litter that turtles may ingest.
Association between per- and polyfluoroalkyl substances and sex hormone levels in males based on human studies
22 Jan 2024 | Ecotoxicol Environ Saf
In a meta-analysis of 12 studies involving 7506 participants, exposure to PFNA and PFOA was found to be negatively correlated with male testosterone levels, emphasizing the need to consider these chemicals as potential risk factors for male reproductive health.
Evaluation of per- and polyfluoroalkyl substances (PFAS) released from two Florida landfills based on mass balance analyses
21 Jan 2024 | Waste Manag
The PFAS mass flux leached from disposed solid waste was found to be approximately 1-3% of the total amount, with the majority captured by leachate collection systems. These results may help prioritize waste management strategies and PFAS treatments over an estimated release period of at least 40 years.
Elevated levels of serum per-and poly-fluoroalkyl substances (PFAS) in contact lens users of US young adults
16 Jan 2024
Analysis of NHANES data revealed that contact lens users in the U.S. young adult population, particularly females, exhibit higher serum concentrations of PFAS such as PFOA and PFOS, suggesting that contact lens use may contribute significantly to PFAS body burden and pose a potential public health concern.
Occurrence of perfluoroalkyl substances in canned tuna and their impact on food safety
16 Jan 2024 | Food Control
The study highlights the potential risk of food contamination from PFAS, particularly in canned tuna, emphasizing concerns about their toxicity as endocrine disruptors, immunosuppressants, and carcinogens, with detected PFOS and PFNA levels below the established Tolerable Weekly Intake for the average Italian consumer but posing a potential concern for high consumers due to multiple sources of PFAS intake.
Tree barks for retrospective measurement and source appointment of airborne perfluoroalkyl and polyfluoroalkyl substances
16 Jan 2024 | Environ. Pollut.
Tree bark was found to be a valuable bioindicator for assessing airborne PFAS pollution, offering a long-term perspective on historical PFAS emissions and allowing for the characterization and tracking of sources, as demonstrated in a study of eight cities in southern Jiangsu Province, China.
Evaluating the toxicokinetics of some metabolites of a C6 polyfluorinated compound, 6: 2 fluorotelomer alcohol in pregnant and nonpregnant rats after oral exposure to the parent compound
16 Jan 2024 | FCT
Following oral exposure, both pregnant and nonpregnant rats exhibited potential biopersistence of 6:2 fluorotelomer alcohol (6:2 FTOH) and its metabolites, particularly 5:3 fluorotelomer carboxylic acid (5:3A), highlighting the need for additional research on human health implications.
Per/Polyfluoroalkyl Substances (PFASs) in a Marine Apex Predator (White Shark, Carcharodon carcharias) in the Northwest Atlantic Ocean
14 Jan 2024 | ACS Environmental Au
This study highlighted the accumulation of PFAS in plasma and muscle tissue of white sharks in the Northwest Atlantic Ocean far from pollution sources and noted some geographical differences in PFAS body burdens that may be due to differences in the diet among these distinct shark populations.
Maternal serum concentrations of per- and polyfluoroalkyl substances and childhood acute lymphoblastic leukemia
13 Jan 2024 | JNCI
Maternal exposure to certain PFAS during pregnancy, particularly MeFOSAA, is associated with an increased risk of childhood acute lymphoblastic leukemia, with notable connections to elevated levels of PFOS, suggesting a potential link between these environmental chemicals and the development of the most common childhood cancer.
Passive Sampler Derived Profiles and Mass Flows of Perfluorinated Alkyl Substances (PFASs) across the Fram Strait in the North Atlantic
10 Jan 2024 | Environ. Technol. Lett.
PFAS were found at different depths across the Fram Strait, showing long-range marine transport and suggesting that PFAS in the Arctic are governed by a feedback loop between the Atlantic and Arctic oceans as well as atmospheric transport.
Association of prenatal exposure to perfluorinated and polyfluoroalkyl substances with childhood neurodevelopment: A systematic review and meta-analysis
10 Jan 2024 | Ecotoxicol Environ Saf
A meta-analysis on prenatal exposure to PFAS suggests a sex-specific relationship, revealing that PFOS, PFOA, and PFHxS are associated with decreased performance IQ in boys but PFOS was linked to increased performance IQ in girls, while PFAS are linked to executive function impairments in children without a significant association with behavioral difficulties.
Toxicity Assessment of Mixed Exposure of Nine Perfluoroalkyl Substances at Concentrations Relevant to Daily Intake
10 Jan 2024 | Toxics
This study exposed mice to a mixture of PFAS at levels equivalent to estimated daily human intake, revealing that even low concentrations of PFAS caused liver tissue changes and altered gene expression related to metabolism and cancer, emphasizing the need for thorough toxicity assessments of these persistent environmental contaminants.
Assessing potential human health and ecological implications of PFAS from leave-in dental products
3 Jan 2024 | Toxicol Ind Health
PFBA and PFOS were found in low levels in night guards with no detection in whitening trays, suggesting these dental products are unlikely to pose health concerns or contribute significantly to environmental PFAS exposure compared to exposure from food and water.
Binding of Per- and Polyfluoroalkyl Substances (PFAS) to Serum Proteins: Implications for Toxicokinetics in Humans
3 Jan 2024 | Environ Sci Technol
PFAS binding to major blood serum proteins is thought to affect toxicity, transport, and half-lives in the body. This study found shorter-chain PFAS showing a stronger binding to human serum albumin and longer-chain PFAS displaying a greater affinity for globulins, emphasizing the significance of understanding these interactions for more precise assessments of PFAS impact on human health in epidemiological studies.
Investigating the progression of preeclampsia through a comprehensive analysis of genes associated with per- and polyfluoroalkyl substances
2 Jan 2024 | Toxicol Mech Methods
Using advanced analysis of genetic data, researchers identified a potential link between PFAS and the risk of preeclampsia, suggesting that these environmental factors may play a role in the development of the disease, and highlighted six genes with diagnostic potential for preeclampsia.