Association of co-exposure to organophosphate esters and per- and polyfluoroalkyl substances and mixture with cardiovascular-kidney-liver-metabolic biomarkers among Chinese adults
4 Jun 2024 | Ecotoxicol Environ Saf
Exposure to common environmental contaminants like organophosphate esters and PFAS, especially PFHxS and PFNA, is associated with disruptions in liver function and cholesterol levels, suggesting potential risks for chronic diseases due to their widespread presence in the human body.
Non-targeted analysis of per-and polyfluorinated substances in consumer food packaging
3 Jun 2024 | Chemosphere
A non-targeted workflow utilizing high-resolution mass spectrometry successfully detected previously unknown PFAS compounds in diverse consumer food packaging samples, revealing the presence of several compounds and emphasizing the prevalence of both emerging and legacy PFAS in food packaging materials.
The bioaccumulation and ecotoxicity of co-exposure of per(poly)fluoroalkyl substances and polystyrene microplastics to Eichhornia crassipes
3 Jun 2024 | Water Res
Gen X and F-53B, used as alternatives to PFOA and PFOS, respectively, show significant bioaccumulation and eco-environmental risks, especially when co-exposed with polystyrene microplastics, which increase their bioavailability and toxicity to the aquatic plant Eichhornia crassipes.
[Report] PFAS Management at Airports: A Guide
1 Jun 2024 | National Academy of Sciences
Developed as a guideline for airport personnel and aviation professionals, the summary underscores the challenges posed by PFAS contaminants in firefighting foams, highlighting the need to manage uncertainties in regulatory requirements, disposal practices, and health and safety measures while anticipating stricter standards for PFAS compounds.
Impact of tightening environmental regulations against long-chain perfluoroalkyl acids on composition of durable water repellents containing side-chain fluorinated polymers
1 Jun 2024 | Sci. Total Environ.
Increased environmental regulations on long-chain PFAAs may have led to a shift towards increased use of short-chain PFAAs in durable water repellents, underscoring the importance of understanding regulatory impacts on DWR composition to guide their use and end-of-life treatment.
Exogenous factors associated with legacy PFAS concentrations in the general US population: NHANES 1999-2018
31 May 2024 | Water Emerging Contaminants & Nanoplastics
Understanding the factors that influence individual levels of PFAS chemicals, such as demographic and lifestyle characteristics, can help tailor legislation and interventions to reduce exposure and protect at-risk groups, as shown by this study analyzing data from nearly 15,000 people across the U.S.
Non-Targeted PFAS Suspect Screening and Quantification of Drinking Water Samples Collected through Community Engaged Research in North Carolina's Cape Fear River Basin
31 May 2024 | Toxics
A community-engaged research approach in North Carolina discovered that drinking water samples from the Cape Fear River basin contained several PFAS compounds, including PFOA and PFOS levels that exceeded the EPA's limit of 4 ng/L, and these results were shared with local residents to help them reduce their exposure.
Maternal F-53B exposure during pregnancy and lactation affects bone growth and development in male offspring
27 May 2024 | Ecotoxicol Environ Saf
Maternal exposure to F-53B, a highly persistent PFOS alternative, in mice during pregnancy and lactation impairs bone growth and development in male offspring, potentially leading to osteoporosis-like symptoms, through disruption of liver function and bone metabolism pathways.
Machine learning–enhanced molecular network reveals global exposure to hundreds of unknown PFAS
24 May 2024 | Sci Adv
Using machine learning, an automatic PFAS identification platform accurately identified unknown PFAS chemicals in environmental samples, offering improved performance over current methods and revealing numerous previously undetected PFAS in wastewater and other global samples.
Current understanding on the transformation and fate of per-and polyfluoroalkyl substances before, during, and after thermal treatment of biosolids
24 May 2024 | J. Chem. Eng.
Thermal treatment methods like incineration, pyrolysis, and gasification can potentially destroy PFAS in biosolids, but optimizing treatment conditions and understanding the complete process remains challenging.
Immune cell profiles associated with human exposure to perfluorinated compounds (PFAS) suggest changes in Natural Killer, T helper and T cytotoxic cell subpopulations
23 May 2024 | Environ Res
Exposure to various PFAS chemicals, even at low levels, is associated with changes in immune cell subpopulations, potentially explaining the immunosuppressive effects observed in epidemiological studies.
A multi-platform approach for the comprehensive analysis of per-and polyfluoroalkyl substances (PFAS) and fluorine mass balance in commercial ski wax products
21 May 2024 | Analytica Chimica Acta
The fluorine content of ski waxes was tested, finding that while traditional analytical methods identified only a small fraction of fluorine as extractable organic fluorine, the majority remained unidentified, suggesting the presence of other PFAS not detected by standard techniques, which highlights the need for more comprehensive analysis methods in assessing PFAS exposure risks in consumer products.
[Report] Recycling of Solar Panels: Comparison of scenarios for a more circular and safe product chain
20 May 2024 | RIVM
The Netherlands aims for a circular economy by 2050 and is developing recycling technologies for solar panels, with a focus on addressing hazardous substances like PFAS found in the panels' backsheets, to ensure safe and sustainable disposal as large-scale panel retirement begins in five years.
Use of Tox21 screening data to profile PFAS bioactivities on nuclear receptors, cellular stress pathways, and cytochrome p450 enzymes
17 May 2024 | J Hazard Mater
Analyzing Tox21 screening data, researchers identified new potential targets/pathways and confirmed known ones for non-legacy PFAS, notably revealing their inhibition of cytochromes P450s (CYPs), particularly one that plays a role in metabolizing drugs and toxins, shedding light on PFAS toxicity mechanisms.
Linking exposure to per- and polyfluoroalkyl substances (PFAS) in house dust and biomonitoring data in eight impacted communities
17 May 2024 | Environ Int
In communities impacted by drinking water contamination from PFAS, household dust was found to significantly correlate with serum PFAS levels, suggesting residential exposure via indoor pathways, with factors like age, duration of residence, cleaning habits, and product usage influencing exposure levels.