Insights into the Dermal Absorption, Deposition, and Elimination of Poly- and Perfluoroalkyl Substances in Rats: The Importance of Skin Exposure

23 Nov 2022 | Environ Sci Technol

Dermal absorption of PFAS can be long-lasting and contribute considerably to the body burden of PFAS in a human model species.

Prenatal Exposure to Per- and Polyfluoroalkyl Substances, Maternal Thyroid Dysfunction, and Child Autism Spectrum Disorder

23 Nov 2022 | Endocrinol Metab (Seoul)

A review of relevant studies found that PFAS exposure may lead to thyroid dysfunction and childhood developmental abnormalities.

What Happens In Utero Does Not Stay In Utero: a Review of Evidence for Prenatal Epigenetic Programming by Per- and Polyfluoroalkyl Substances (PFAS) in Infants, Children, and Adolescents

22 Nov 2022 | Curr Environ Health Rep

This review covers the relationship between prenatal exposure to PFAS and epigenetic modifications in infants, children, and adolescents  over  18 years of age.

Bone mass density following developmental exposures to perfluoroalkyl substances (PFAS): a longitudinal cohort study

19 Nov 2022 | Environ Health

PFAS exposures in childhood are negatively associated with overall bone mass density, with the strongest association seen for PFNA amongst 5-year-olds.

Biota-Sediment Accumulation Factors (BSAFs) for Per- and Polyfluorinated Substances (PFAS)

18 Nov 2022 | Environ Toxicol Chem

A summary of biota-sediment accumulation factors is given for many PFAS, and the largest research gap identified is understanding the effects of concentration and mixtures upon bioaccumulation from sediments.

First Evidence of Prenatal Exposure to Emerging Poly- and Perfluoroalkyl Substances Associated with E-Waste Dismantling: Chemical Structure-Based Placental Transfer and Health Risks

18 Nov 2022 | Environ Sci Technol

Electronic waste dismantling contributes to adult and fetal exposure to PFAS, with 6:2 FTSA, 6:2 Cl-PFESA, and PFOPA identified as major emerging PFAS with trans-placemental transfer efficiencies higher than that of PFOS.

[Public Comments] New Jersey Department of Environmental Protection Comments on Draft World Health Organization Drinking Water Quality Guidelines for PFOA and PFOS

17 Nov 2022

NJDEP identified the need for many revisions in both the factual information and the conclusions about health effects, treatment removal, and other topics discussed in the draft WHO document.

Nontargeted screening reveals fluorotelomer ethoxylates in indoor dust and industrial wastewater.

15 Nov 2022 | Environ. Int.

FTEOs were detected in 60% of indoor dust samples and c. 40% of industrial effluent samples, with the highest concentrations in healthcare facility dust and the effluents from electroplating facilities, manufacturers of cosmetics and personal care products, and linen cleaning services for healthcare and work uniforms.

Associations of per- and polyfluoroalkyl substances (PFAS) and their mixture with oxidative stress biomarkers during pregnancy

14 Nov 2022 | Environ Intern

PFOS was associated with elevated oxidative stress levels during pregnancy, which may affect fetal development.

Paints: A Source of Volatile PFAS in Air - Potential Implications for Inhalation Exposure

11 Nov 2022 | Environ Sci Technol

Common paints were found to contain 6:2 FTOH and 6:2 diPAP that accounted for up to 17% of total fluorine, with 40% of FTOH mass lost upon drying. Exposure estimates suggest that PFAS exposure while painting could exceed recommended reference doses for children and adults.

Apparent Half-Lives of Chlorinated-Perfluorooctane Sulfonate and Perfluorooctane Sulfonate Isomers in Aviation Firefighters

11 Nov 2022 | Environ Sci Technol

The average half-life of Cl-PFOS among firefighters with previous exposure to fluorinated AFFF was 5.0 years, although other forms of PFOS had half-lives ranging from 4-11.5 years.

Per- and Poly-Fluoroalkyl Substances in Runoff and Leaching from AFFF-Contaminated Soils: a Rainfall Simulation Study

10 Nov 2022 | Environ Sci Technol

PFAS concentrations in AFFF-contaminated soils declined significantly after the first rainfall event, but desorption and transport in both runoff and leachates persisted over several rainfall events.

[Public Comments] International Society for Environmental Epidemiology Comments on Draft World Health Organization Drinking Water Quality Guidelines for PFOA and PFOS

10 Nov 2022 | ISEE Website

The ISEE, a leading scientific association in environmental epidemiology that impacts research, training, and policy worldwide, identified that the provisional WHO guidelines neither protect human health nor include the latest scientific literature.

Legacy and emerging airborne per- and polyfluoroalkyl substances (PFAS) collected on PM2.5 filters in close proximity to a fluoropolymer manufacturing facility

9 Nov 2022 | Environ Sci Process Impacts

Twelve emerging and ten legacy PFAS compounds were detected in aerosol samples around a fluoropolymer manufacturing facility at concentrations higher than at regional background sites, suggesting the manufacturing facility as the local source for these compounds.

Controlled uptake of PFOA in adult specimens of Paracentrotus lividus and evaluation of gene expression in their gonads and embryos

9 Nov 2022 | Environ Sci Pollut Res Int

PFOA is persistent and bioaccumulative in sea urchins and adversely affects their health by causing significant changes in the expression of some key target genes and the occurrence of developmental anomalies in the embryos.