Red blood cell folate modifies the association between serum per- and polyfluoroalkyl substances and antibody concentrations in U.S. adolescents

30 Jan 2023 | Environ. Sci. Technol.

Associations between higher serum PFAS and lower disease antibodies were found to be significant only in adolescent groups with lower folate levels, suggesting that folate may be used as a mitigation measure against immune-related PFAS effects.

Historical Trend of Exposure to Perfluoroalkyl Surfactants PFOA, ADV, and cC6O4 and its Management in Two Perfluoroalkyl Polymers Plants, Italy

28 Jan 2023 | Ann Work Expo Health

PFAS blood contamination was reduced 5- to 136-fold in fluoropolymer industry workers after several initiatives to reduce exposure.

Levels and distribution profiles of Per- and Polyfluoroalkyl Substances (PFAS) in a high Arctic Svalbard ice core

27 Jan 2023 | Sci Total Environ

Analysis of C2-C11 PFCAs in an arctic ice core found that TFA represented 71 % of the total mass of PFCAs and exhibited an increasing atmospheric deposition trend over time.

Geographic and demographic variability in serum PFAS concentrations for pregnant women in the United States

25 Jan 2023 | J Expo Sci Environ Epidemiol

Mapping showed that participants’ proximity to local point sources can overshadow expected trends with demographic information, and environmental justice considerations were discussed.

Systematic review and meta-analysis of birthweight and PFNA exposures

24 Jan 2023 | Environ Res

Data analysis techniques allowing for more studies to be included in this review resulted in a stronger connection between birthweight deficits and PFNA exposure compared to previous PFAS meta-analyses.

Leaching of Perfluoroalkyl Acids during Unsaturated Zone Flushing at a Field Site Impacted with Aqueous Film Forming Foam

23 Jan 2023 | Environ Sci Technol

Remedial approaches that remove only a modest fraction of the PFAA mass in soil may be protective of underlying groundwater, particularly for some perfluorinated sulfonates.

Bioaccessibility of per- and polyfluoroalkyl substances in food and dust: Implication for more accurate risk assessment

20 Jan 2023 | Sci Total Environ

The bioaccessibility of PFAS was higher in simulated animal foods than in simulated vegetable foods, and the bioaccessibility of most very long-chain PFAS was higher in food than in dust.

Optimizing Chemicals Management in the United States and Canada through the Essential-Use Approach

19 Jan 2023 | Environ Sci Technol

If optimized and expanded into regulatory systems in the United States and Canada, other policymaking bodies, and businesses, the essential-use approach can improve chemicals management and shift the market toward safer chemistries that benefit human and ecological health.

The role of PFAS in unsettling ocean carbon sequestration

18 Jan 2023 | Environ Monit Assess

The harmful effects of PFAS on marine ecosystems may weaken the ocean’s ability to capture and hold global warming carbon emissions.

Evaluation of per- and polyfluoroalkyl substances (PFAS) in leachate, gas condensate, stormwater and groundwater at landfills

17 Jan 2023 | Chemosphere

To prioritize and improve PFAS remediation from discarded consumer products, relationships were found between PFAS and landfill characteristics, including aqueous samples like leachate and stormwater.

Prenatal exposure to per- and polyfluoroalkyl substances and childhood autism-related outcomes

12 Jan 2023 | Epidemiology

Mothers’ prenatal blood concentrations of PFNA may be associated with modest increases in their child’s autism-related traits.

PFAS Biotransformation Pathways: A Species Comparison Study

12 Jan 2023 | Toxics

A metabolic pathway map was made to aid researchers in determining possible PFAS breakdown products in fish when no metabolic data is present.

A Proposed approach to defining per- and polyfluoroalkyl substances (PFAS) based on molecular structure and formula

11 Jan 2023 | Integr Environ Assess Manag

A definition of PFAS was proposed based on four substructures and any structures where the molecular formula is at least 30% fluorine by atom count.

Occurrence and implications of per and polyfluoroalkyl substances in animal feeds used in laboratory toxicity testing

10 Jan 2023 | Sci Total Environ

PFAS contamination in animal feed was found to be pervasive, which is significant because unintended PFAS exposure in control animals from feed can significantly bias toxicity testing.

In utero exposure to perfluoroalkyl substances and early childhood BMI trajectories: A mediation analysis with neonatal metabolic profiles

9 Jan 2023 | Sci Total Environ

Prenatal PFAS exposure was associated with persistently increased BMI in childhood.