Association between per- and polyfluoroalkyl substances exposure and risk of diabetes: a systematic review and meta-analysis
15 Aug 2022 | J Expo Sci Environ Epidemiol
Exposure to PFAS may increase diabetes risk among the general population, and PFOA may exert a non-monotonic dose-response effect on diabetes risk.
Associations of single and multiple perfluoroalkyl substances exposure with folate among adolescents in NHANES 2007-2010
15 Aug 2022 | Chemosphere
Exposure to PFOS, PFOA, PFNA, and PFDA was associated with lower blood folate concentrations.
Exposure to perfluoroalkyl substances and risk of hepatocellular carcinoma in a multiethnic cohort
8 Aug 2022 | JHEP Reports
Exposure to high PFOS levels was associated with an increased risk of non-viral liver cancer, likely via alterations in glucose, amino acid, and bile acid metabolism.
Exposure to perfluoroalkyl substances and risk of hepatocellular carcinoma in a multiethnic cohort
8 Aug 2022 | JHEP Reports
Exposure to high PFOS levels is associated with an increased risk of the most common type of liver cancer.
Influence of microplastics on the photodegradation of perfluorooctane sulfonamide (FOSA)
8 Aug 2022 | Res. J. Environ. Sci.
Microplastics could act as PFAS concentrators, making the PFAS more resistant to degradation.
Coupling a pathway-oriented approach with tailor-made monitoring as key to well-performing regionalized modelling of PFAS emissions and river concentrations
4 Aug 2022 | Sci Total Environ
A model was developed to assess PFAS emission pathways to rivers, and revealed the dominant PFOS contamination source was municipal wastewater treatment plants.
Neurotransmission Targets of Per- and Polyfluoroalkyl Substance Neurotoxicity: Mechanisms and Potential Implications for Adverse Neurological Outcomes
3 Aug 2022 | Chem Res Toxicol
PFAS may be neurotoxic and is associated with chronic and age-related psychiatric illnesses and neurodegenerative diseases.
Outside the Safe Operating Space of a New Planetary Boundary for Per-and Polyfluoroalkyl Substances (PFAS)
2 Aug 2022 | ES&T
PFAS have been detected at unsafe levels in rain globally, leading to the conclusions that the spread of PFOS, PFOA, PFHxS, and PFNA in the atmosphere has exceeded levels of concern for chemical pollution and that PFAS uses and emissions should be rapidly restricted.
The PFAS-Tox Database: A systematic evidence map of health studies on 29 per- and polyfluoroalkyl substances
1 Aug 2022 | Environ. Int.
In this summary of the PFAS-Tox Database we provide examples of data gaps and clusters revealed by the database, with the goal of helping direct future research efforts, facilitate systematic reviews (e.g. on immune effects, mixtures of PFAS, or effects of short chain PFAS), inform regulatory risk assessments, and improve opportunities for cross-disciplinary coordination.
The Association of Per-and Polyfluoroalkyl Substances Serum Levels and Allostatic Load by Country of Birth and the Length of Time in the United States
1 Aug 2022 | Int. J. Environ. Res. Public Health
Foreign-born individuals tend to have higher levels of serum PFAS the longer they stay in the United States.
Leveraging Systematic Reviews to Explore Disease Burden and Costs of Per and Polyfluoroalkyl Substance
1 Aug 2022 | Exposure and Health
This study identified at least $5.5 billion in annual disease burden and social costs due to long-chain PFAS exposure, demonstrating that regulatory actions to limit PFAS use and remediate contaminated water may produce substantial economic benefits.
Uptake of individual and mixed per- and polyfluoroalkyl substances (PFAS) by soybean and their effects on functional genes related to nitrification, denitrification, and nitrogen fixation
29 Jul 2022 | Sci. Total Environ.
The synergistic effect of a PFAS mixture increased the uptake of individual PFAS in soybeans, which led to changes in genes involved in the nitrogen cycle.
Per-and polyfluoroalkyl substances in the atmosphere of waste management infrastructures: Uncovering secondary fluorotelomer alcohols, particle size distribution, and human inhalation exposure
29 Jul 2022 | Environ. Int.
PFAS were prevalent in the air and in particulate matter near landfills and wastewater treatment plants, and modeling demonstrated that fine and ultrafine particles may carry PFAS into the lung alveoli.
Per- and polyfluoroalkyl substances (PFASs) in consumable species and food products
28 Jul 2022 | J Food Sci Technol
This review found that legacy PFAS remain in high abundance and that proximity to factories and fluorochemical industries results in potentially hazardous levels of PFAS contamination in all types of food products.
Increasing Accumulation of Perfluorocarboxylate Contaminants Revealed in an Antarctic Firn Core (1958–2017)
26 Jul 2022 | ES&T
PFCA and PFBA accumulation in snow increased, and although chemical fluxes of PFOA and PFNA peaked in 2009–2013, there is little evidence of a decline in PFAAs despite supposed recent global curtailments in their production.