Prenatal and postnatal exposure to PFAS and cardiometabolic factors and inflammation status in children from six European cohorts.

14 Sep 2021 | Environ Int

Prenatal, rather than postnatal, PFAS exposure might contribute to increased obesity in children.

Evaluation of the acute toxicity and neurodevelopmental inhibition of perfluorohexanoic acid (PFHxA) in zebrafish embryos

14 Sep 2021 | Ecotoxicol Environ Saf

High levels of PFHxA exposure was associated with permanent neurological damage in a human model organism.

Comparative characterization of microbial communities that inhabit PFAS-rich contaminated sites: A case-control study

14 Sep 2021 | J Hazard Mater

Soil microbial communities were found to have adverse reactions to PFAS which may put crops at risk.

Transport and environmental risks of perfluoroalkyl acids in a large irrigation and drainage system for agricultural production

11 Sep 2021 | Environ Int

Up to 40% of tolerant daily intake came from humans eating contaminated aquatic organisms.

Exposure to Perfluoroalkyl Substances and Glucose Homeostasis in Youth

8 Sep 2021 | Environ Health Perspect

Youth exposure to PFHxS was associated with abnormal metabolism in females, especially after puberty.

Exposure to a mixture of legacy, alternative, and replacement per- and polyfluoroalkyl substances (PFAS) results in sex-dependent modulation of cholesterol metabolism and liver injury

8 Sep 2021 | Environ Int

Exposure of mice to a mixture of PFAS results in abnormal modulation of cholesterol levels leading to increased liver weight and inflammation.

Systemic toxicity induced by topical application of heptafluorobutyric acid (PFBA) in a murine model

8 Sep 2021 | Food Chem Toxicol

Sustained dermal exposure to PFBA induces liver toxicity and raises concerns of short-chain PFAS being promoted as safer alternatives.

The role of maternal high fat diet on mouse pup metabolic endpoints following perinatal PFAS and PFAS mixture exposure

8 Sep 2021 | Toxicology

PFAS mixtures were found to have increased detrimental effects, especially when transferred from mother to offspring.

Use of glioma to assess the distribution of patterns of perfluoroalkyl and polyfluoroalkyl substances in human brain

8 Sep 2021 | Environ Res

PFAS, including short chains, were found inside the brain circumnavigating the blood-brain barrier.

Potency ranking of per- and polyfluoroalkyl substances using high-throughput transcriptomic analysis of human liver spheroids

8 Sep 2021 | Toxicol Sci

Longer-chain compounds (7 to 10 carbons) were more likely to induce changes in gene expression.

PFAS and potential adverse impacts on bone and adipose tissue through interactions with PPAR-gamma

8 Sep 2021 | Endocrinology

PFAS was found to affect cell differentiation and bone development in several human model species.

Associations between polyfluoroalkyl substance and organophosphate flame retardant exposures and telomere length in a cohort of women firefighters and office workers in San Francisco

7 Sep 2021 | Environ Health

Positive associations between PFAS and telomere length in women workers, with larger effects seen among firefighters as compared to office workers.

Hexafluoropropylene oxide dimer acid (HFPO-DA) induced developmental cardiotoxicity and hepatotoxicity in hatchling chickens: Roles of peroxisome proliferator activated receptor alpha

4 Sep 2021 | Environ Pollut

Exposure to HFPO-DA induced developmental cardio-toxicity and hepatotoxicity in hatchling chickens similar to PFOA

The Nrf2a pathway impacts zebrafish offspring development with maternal preconception exposure to perfluorobutanesulfonic acid

2 Sep 2021 | Chemosphere

PFBS exposures were found to alter egg and embryo development, when exposure occurs preconception.

Per/polyfluoroalkyl substances production, applications and environmental impacts

31 Aug 2021 | Bioresource Tech.

Current chemical and biological remediation technologies are expensive/not effective and thus new remediation technologies must be developed.