Early-life exposure to perfluoroalkyl substances in relation to serum adipokines in a longitudinal birth cohort

31 Aug 2021 | Environ Res

Childhood concentrations of PFASs were associated with decreased regulation of appetite and fat storage.

Exposure to hexafluoropropylene oxide dimer acid (HFPO-DA) disturbs the gut barrier function and gut microbiota in mice

31 Aug 2021 | Environ Pollut

Potential gut toxicity of HFPO-DA and is perceived as a major problem of health risk that affects inflammation, gut barrier dysfunction, and gut microbiota disturbance in mammals.

Understanding the Impact of Perfluorinated Compounds on Cardiovascular Diseases and Their Risk Factors: A Meta-Analysis Study

31 Aug 2021 | Int J Environ Res Public Health

PFOA and PFOS were positively associated with developing cardiovascular diseases and their risk factors.

Rapid Determination of Per- and Polyfluoroalkyl Substances (PFAS) in Harbour Porpoise Liver Tissue by HybridSPE-UPLC-MS/MS

31 Aug 2021 | Toxics

A new analytical method was optimized for use on mammalian tissues with up to 89% detection.

Exposure to GenX and Its Novel Analogs Disrupts Hepatic Bile Acid Metabolism in Male Mice

31 Aug 2021 | Environ Sci Technol

The inhibition of nutrient absorption may be a prominent adverse effect induced by exposure to GenX, its analogs, and PFOA.

Analysis of per- and poly-fluoroalkyl substances (PFAS) in processed foods from FDA's Total Diet Study

31 Aug 2021 | Anal Bioanal Chem

PFAS features detected by LC-MS/MS correlated well in abundance with LC-IMS-MS data; however, LC-IMS-MS identified a number of additional PFAS, many known to be components of firefighting foams.

Early pregnancy loss: Do Per- and polyfluoroalkyl substances matter?

31 Aug 2021 | Environ Int

Overall, we suggest that most PFAS were not associated with early pregnancy loss at the current exposure levels.

Perfluorobutanoic acid (PFBA): No high-level accumulation in human lung and kidney tissue

30 Aug 2021 | Int J Hyg Environ Health

Contrary to previous findings, analysis of short-chain PFAS in human lungs and kidney indicates PFBA is not likely to accumulate in these tissues.

The occurrence of per- and polyfluoroalkyl substances (PFASs) in fluoropolymer raw materials and products made in China

25 Aug 2021 | J Environ Sci (China)

Generally, the levels of PFOA in raw materials were higher than in products, implying that PFOA in the emulsion/dispersion resin could be partly removed during the polymerization or post-processing steps.

Occurrence of perfluoroalkyl substances (PFASs) in marine plastic litter from coastal areas of Central Chile

25 Aug 2021 | Mar Pollut Bull

Long-chain PFAS, which can be metabolically degraded into PFOS, were found on six South American beaches in plastic debris.

The Dilemma of Perfluorooctanoate (PFOA) Human Half-life

25 Aug 2021 | Regul Toxicol Pharmacol

Based on information from both human observational studies and clinical data, we proposed a range for the half-life for PFOA of 0.5 to 1.5 years, which would likely raise many existing regulatory safe levels if all other parameters stayed the same.

External and internal human exposure to PFOA and HFPOs around a mega fluorochemical industrial park, China: Differences and implications

25 Aug 2021 | Environ Int

PFAS were detected in human hair, and their compositions were similar to those in human serum, suggesting that hair is a good non-invasive indicator for long-term exposure to legacy long-chain perfluoroalkyl carboxylic acids and HFPOs.

Perfluoroalkyl substances (PFAS) in drinking water and risk for polycystic ovarian syndrome, uterine leiomyoma, and endometriosis: A Swedish cohort study

25 Aug 2021 | Environ Int

Exposure to high levels of PFAS in drinking water was associated with an increased risk of enlarged and irritated ovaries.

Chlorinated polyfluoroalkyl ether sulfonic acids in fish, dust, drinking water and human serum: From external exposure to internal doses

25 Aug 2021 | Environ Int

The modeled serum concentrations of 6:2 Cl-PFESA were higher than its observed levels hinting at its gradually increasing exposure levels in the general population.

Removal of per- and poly-fluoroalkyl substances (PFASs) by wetlands: Prospects on plants, microbes and the interplay

25 Aug 2021 | Sci Total Environ

The choice of plants and bacterial species is however crucial for the bioremediation of PFAS, and the system efficiency relies on species-specific, sediment-specific, and pollutant-specific principles.