Showing 181-195 of 540
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The PFAS-Tox Database: A systematic evidence map of health studies on 29 per- and polyfluoroalkyl substances
Science
1 Aug 2022 | Environ. Int.
In this summary of the PFAS-Tox Database we provide examples of data gaps and clusters revealed by the database, with the goal of helping direct future research efforts, facilitate systematic reviews (e.g. on immune effects, mixtures of PFAS, or effects of short chain PFAS), inform regulatory risk assessments, and improve opportunities for cross-disciplinary coordination.
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EPA Whistleblowers Provide New Evidence Of Ongoing Failure To Assess Dangerous Chemicals
News
1 Aug 2022 | The Intercept
Managers in the EPA’s New Chemicals Division have refused to assess the risk of cancer and other harms from chemicals deemed to be “corrosive.”
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Association of increased risk of cardiovascular diseases with higher levels of perfluoroalkylated substances in the serum of adults
Science
18 Jul 2022 | Environ Sci Pollut Res Int
A significant relationship between higher serum PFAS concentrations and an increased risk of cardiovascular disease was observed, mainly in males.
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GenX Induces Fibroinflammatory Gene Expression in Primary Human Hepatocytes
Science
15 Jul 2022 | Toxicology
GenX can interfere with metabolic pathways at lower doses and induce abnormal inflammation in human liver cells at higher doses.
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The origin of these highly toxic man-made chemicals
News
10 Jul 2022 | Chicago Tribune
Industry records show 3M and DuPont, the chief manufacturers of PFAS, hid what they knew about the dangers for decades.
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Exposure to perfluoroalkyl substances and neurodevelopment in 2-year-old children: A prospective cohort study
Science
7 Jul 2022 | Environ Int
PFAS exposure during early pregnancy was significantly associated with an adverse neurodevelopmental status at two years of age, raising a serious public health concern.
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Association of Prenatal Exposure to Endocrine-Disrupting Chemicals With Liver Injury in Children
Science
6 Jul 2022 | JAMA Netw Open
Prenatal exposure to mixtures of endocrine-disrupting chemicals, such as PFAS, organochlorine pesticides, and metals, may increase the risk for liver injury in childhood.
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Exposure to perfluoroalkyl substances and neonatal immunoglobulin profiles in the upstate KIDS study (2008-2010)
Science
1 Jul 2022 | Environ Pollut
Early exposure to PFOA and PFOS may disrupt neonatal immunoglobulin levels, weakening neonatal immune systems.
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‘It’s scary as hell’ — PFAS exposure a ‘widespread’ problem for troops, families nationwide
News
30 Jun 2022 | Military Times
Some of the highest concentrations of PFAS chemicals in the country have been found at and around military bases, in large part because of the military’s longtime reliance on the firefighting foam AFFF — PFAS are active ingredients.
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[Perspective] Bone accrual during adolescence: do endocrine disrupting chemicals play a role?
Science
28 Jun 2022 | J Clin Endocrinol Metab
Early-life chemical exposure to phthalates and PFAS may lead to reduced bone mass accrual during adolescence.
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Associations between prenatal exposure to perfluoroalkyl substances and neurobehavioral development in early childhood: A prospective cohort study
Science
28 Jun 2022 | Ecotoxicol Environ Saf
Modest associations found potential developmental neurotoxicity of prenatal PFAS exposure.
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Baltimore’s water system contains PFAS chemicals at levels above new EPA health advisory
News
24 Jun 2022 | The Baltimore Sun
Baltimore’s water system, which serves 1.8 million homes and businesses in the city and Baltimore County, contains measurable levels of so-called ‘forever chemicals’ that the federal Environmental Protection Agency said last week pose health risks even at minute levels.
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Exposure to Per-and Polyfluoroalkyl Substances and Mortality in US Adults: A Population-Based Cohort Study
Science
22 Jun 2022 | Environ. Health Perspect.
High exposure of U.S. adults to PFOS and a PFAS mixture was found to be positively associated with all-cause mortality, heart disease mortality, and cancer mortality.
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The Vitamin D Receptor as a Potential Target for the Toxic Effects of Per-and Polyfluoroalkyl Substances (PFASs)
Science
21 Jun 2022 | SSRN
Computer modeling suggested that dozens of commonly used PFAS may competitively bind to vitamin D receptors, which could potentially lead to harmful effects on immune, endocrine, and bone homeostasis.
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‘Forever chemicals’ linked to high blood pressure in women
News
20 Jun 2022 | The Washington Post
Researchers have linked PFAS to high blood pressure in middle-aged women, adding to the long list of health risks associated with the pollutants.