Showing 451-465 of 540
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Per- and Polyfluoroalkyl Substance Toxicity and Human Health Review: Current State of Knowledge and Strategies for Informing Future Research
Science
13 Oct 2020 | Environ Toxicol Chem
The goals of this review are to assess the state of the science regarding the toxicological effects of PFAS, and to develop strategies for advancing knowledge on the health effects of this large family of chemicals.
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Are Fluoropolymers Really of Low Concern for Human and Environmental Health and Separate from Other PFAS?
Science
12 Oct 2020 | ES&T
Given fluoropolymers’ extreme persistence; emissions associated with their production, use, and disposal; and a high likelihood for human exposure to PFAS, their production and uses should be curtailed except in cases of essential uses.
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Perfluorooctanesulfonic acid (PFOS) and perfluorohexanesulfonic acid (PFHxS) alter the blood lipidome and the hepatic proteome in a murine model of diet-induced obesity.
Science
7 Oct 2020 | Toxicol. Sci.
PFOS and PFHxS were found to increase the risk of metabolic and inflammatory disease when a diet high in fat was consumed.
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Associations between serum concentrations of perfluoroalkyl substances and DNA methylation in women exposed through drinking water: A pilot study in Ronneby, Sweden.
Science
6 Oct 2020 | Env. Int.
Women exposed to PFAS contaminated water were found to likely be at risk of hormone disruption and cancer due to altered DNA methylation.
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Perfluorooctane sulfonic acid (PFOS) exposure during Pregnancy Increases Blood Pressure and Impairs Vascular Relaxation Mechanisms in the Adult Offspring
Science
6 Oct 2020 | Reprod. Toxicol.
PFOS exposure during prenatal life caused low birth weight followed by catch-up growth only in females and lead to hypertension and altered muscle performance in both males and females.
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Effects of perfluoroalkyl carboxylic acids on the uptake of sulfobromophthalein via organic anion transporting polypeptides in human intestinal Caco-2 cells.
Science
29 Sep 2020 | Biochem Biophys Rep
PFHpA, PFOA, PFNA, PFDA, and PFUnDA, significantly decreased the ability to take up and move hormones in human cells.
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Perfluorooctanoic acid (PFOA) inhibits the gap junction intercellular communication and induces apoptosis in human ovarian granulosa cells
Science
29 Sep 2020 | Reprod. Toxicol.
PFOA was associated with endocrine disruption causing cell death in human ovarian cells.
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Chemical Characterization of a Legacy Aqueous Film-Forming Foam Sample and Developmental Toxicity in Zebrafish
Science
29 Sep 2020 | Environ. Health Perspect.
100 individual PFAS were detected in AFFF with PFOS being the most toxic to developing human models species.
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Per- and Polyfluoroalkyl Substance Exposure, Gestational Weight Gain, and Postpartum Weight Changes in Project Viva
Science
28 Sep 2020 | Obesity
PFAS exposure during pregnancy was associated with greater gestational weight gain, weight retention, and weight gain years after pregnancy.
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Review: Evolution of evidence on PFOA and health following the assessments of the C8 Science Panel.
Science
22 Sep 2020 | Environ Int
Former C8 Science Panel members and collaborators comment on current PFOA literature regarding health outcomes finding that epidemiologic evidence remains limited.
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Coronavirus creates delay in Pentagon research for alternative to 'forever chemicals,' official says
News
15 Sep 2020 | The Hill
The coronavirus has caused a delay in researching alternatives to using cancer-linked chemicals in military firefighting foam, the director of the Defense Department’s Strategic Environment Research and Development Program said Tuesday.
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Association between exposure to per- and polyfluoroalkyl substances and blood glucose in pregnant women
Science
15 Sep 2020 | Int J Hyg Environ Health
PFAS exposure was linked to impaired glucose metabolism among young adults.
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Association between exposure to perfluoroalkyl substances and metabolic syndrome and related outcomes among older residents living near a Science Park in Taiwan
Science
15 Sep 2020 | Int J Hyg Environ Health
PFNA and PFOS were found to be positively associated with uric acid levels, especially in elderly males.
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Perfluoroalkyl acids and sulfonamides and dietary, biological and ecological associations in peregrine falcons from the Laurentian Great Lakes Basin, Canada
Science
9 Sep 2020 | Environ. Res.
The study's findings highlighted the importance of integrating dietary, biological, and ecological factors when studying PFAS exposure in birds.
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Neurotoxic Effects of Lactational Exposure to Perfluorooctane Sulfonate on Learning and Memory in Adult Male Mouse
Science
8 Sep 2020 | Food Chem Toxicol
The present study showed that lactational PFOS exposure has a profound, long-lasting neurotoxic effect in the brain and consequently leads to learning and memory deficits.